-
1
-
-
84872534568
-
Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines
-
Li Y, Chan SC, Brand LJ, Hwang TH, Silverstein KAT and Dehm SM: Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines. Cancer Res 73: 483-489, 2013.
-
(2013)
Cancer Res
, vol.73
, pp. 483-489
-
-
Li, Y.1
Chan, S.C.2
Brand, L.J.3
Hwang, T.H.4
Silverstein, K.A.T.5
Dehm, S.M.6
-
2
-
-
84882274167
-
NF- B2/p52 induces resistance to enzalutamide in prostate cancer: Role of androgen receptor and its variants
-
Nadiminty N, Tummala R, Liu C, Yang J, Lou W, Evans CP and Gao AC: NF- B2/p52 induces resistance to enzalutamide in prostate cancer: Role of androgen receptor and its variants. Mol Cancer Ther 12: 1629-1637, 2013.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 1629-1637
-
-
Nadiminty, N.1
Tummala, R.2
Liu, C.3
Yang, J.4
Lou, W.5
Evans, C.P.6
Gao, A.C.7
-
3
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, Han M, Partin AW, Vessella RL, Isaacs WB, Bova GS and Luo J: Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res 69: 16-22, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 16-22
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
Isharwal, S.4
Veltri, R.W.5
Humphreys, E.6
Han, M.7
Partin, A.W.8
Vessella, R.L.9
Isaacs, W.B.10
Bova, G.S.11
Luo, J.12
-
4
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV, Vessella RL and Tindall DJ: Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res 68: 5469-5477, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
5
-
-
77955296562
-
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
-
Sun S, Sprenger CC, Vessella RL, Haugk K, Soriano K, Mostaghel EA, Page ST, Coleman IM, Nguyen HM, Sun H, Nelson PS and Plymate SR: Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. J Clin Invest 120: 2715-2730, 2010.
-
(2010)
J Clin Invest
, vol.120
, pp. 2715-2730
-
-
Sun, S.1
Sprenger, C.C.2
Vessella, R.L.3
Haugk, K.4
Soriano, K.5
Mostaghel, E.A.6
Page, S.T.7
Coleman, I.M.8
Nguyen, H.M.9
Sun, H.10
Nelson, P.S.11
Plymate, S.R.12
-
6
-
-
35148833549
-
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence
-
Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung H and Mudryj M: Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Res 67: 9001-9005, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 9001-9005
-
-
Libertini, S.J.1
Tepper, C.G.2
Rodriguez, V.3
Asmuth, D.M.4
Kung, H.5
Mudryj, M.6
-
7
-
-
0030930049
-
A novel splice site mutation in the androgen receptor gene results in exon skipping and a non-functional truncated protein
-
Lim J, Ghadessy FJ and Yong E: A novel splice site mutation in the androgen receptor gene results in exon skipping and a non-functional truncated protein. Mol Cell Endocrinol 131: 205-210, 1997.
-
(1997)
Mol Cell Endocrinol
, vol.131
, pp. 205-210
-
-
Lim, J.1
Ghadessy, F.J.2
Yong, E.3
-
8
-
-
84861615355
-
AR-Q640X, a model to study the effects of constitutively active C-terminally truncated AR variants in prostate cancer cells
-
Streicher W, Zengerling F, Laschak M, Weidemann W, Höpfner M, Schrader AJ, Jentzmik F, Schrader M and Cronauer MV: AR-Q640X, a model to study the effects of constitutively active C-terminally truncated AR variants in prostate cancer cells. World J Urol 30: 333-339, 2012.
-
(2012)
World J Urol
, vol.30
, pp. 333-339
-
-
Streicher, W.1
Zengerling, F.2
Laschak, M.3
Weidemann, W.4
Höpfner, M.5
Schrader, A.J.6
Jentzmik, F.7
Schrader, M.8
Cronauer, M.V.9
-
9
-
-
80052256577
-
Clusterin inhibition using OGX-011 synergistically enhances HSP90 inhibitor activity by suppressing the heat-shock response in castrate-resistant prostate cancer
-
Lamoureux F, Thomas C, Yin M, Kuruma H, Beraldi E, Fazli L, Zoubeidi A and Gleave ME: Clusterin inhibition using OGX-011 synergistically enhances HSP90 inhibitor activity by suppressing the heat-shock response in castrate-resistant prostate cancer. Cancer Res 71: 5838-5849, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 5838-5849
-
-
Lamoureux, F.1
Thomas, C.2
Yin, M.3
Kuruma, H.4
Beraldi, E.5
Fazli, L.6
Zoubeidi, A.7
Gleave, M.E.8
-
10
-
-
79954624502
-
A novel HSP90 inhibitor delays castrate-resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis
-
Lamoureux F, Thomas C, Yin M, Kuruma H, Fazli L, Gleave ME and Zoubeidi A: A novel HSP90 inhibitor delays castrate-resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis. Clin Cancer Res 17: 2301-2313, 2011.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2301-2313
-
-
Lamoureux, F.1
Thomas, C.2
Yin, M.3
Kuruma, H.4
Fazli, L.5
Gleave, M.E.6
Zoubeidi, A.7
-
11
-
-
84863335299
-
Evidence for efficacy of new HSP90 inhibitors revealed by ex vivo culture of human prostate tumors
-
Centenera MM, Gillis JL, Hanson AR, Jindal S, Taylor RA, Risbridger GP, Sutherland PD, Scher HI, Raj GV, Knudsen KE, Yeadon T, Tilley WD and Butler LM: Evidence for efficacy of new HSP90 inhibitors revealed by ex vivo culture of human prostate tumors. Clin Cancer Res 18: 3562-3570, 2012.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3562-3570
-
-
Centenera, M.M.1
Gillis, J.L.2
Hanson, A.R.3
Jindal, S.4
Taylor, R.A.5
Risbridger, G.P.6
Sutherland, P.D.7
Scher, H.I.8
Raj, G.V.9
Knudsen, K.E.10
Yeadon, T.11
Tilley, W.D.12
Butler, L.M.13
-
12
-
-
79961042759
-
Targeting the regulation of androgen receptor signaling by the heat-shock protein 90 co-chaperone FKBP52 in prostate cancer cells
-
Leon JT de, Iwai A, Feau C, Garcia Y, Balsiger HA, Storer CL, Suro RM, Garza KM, Lee S, Sang Kim Y, Chen Y, Ning Y, Riggs DL, Fletterick RJ, Guy RK, Trepel JB, Neckers LM and Cox MB: Targeting the regulation of androgen receptor signaling by the heat-shock protein 90 co-chaperone FKBP52 in prostate cancer cells. Proc Natl Acad Sci USA 108: 11878-11883, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11878-11883
-
-
De Leon, J.T.1
Iwai, A.2
Feau, C.3
Garcia, Y.4
Balsiger, H.A.5
Storer, C.L.6
Suro, R.M.7
Garza, K.M.8
Lee, S.9
Sang Kim, Y.10
Chen, Y.11
Ning, Y.12
Riggs, D.L.13
Fletterick, R.J.14
Guy, R.K.15
Trepel, J.B.16
Neckers, L.M.17
Cox, M.B.18
-
13
-
-
84870580756
-
Targeting TCTP as a new therapeutic strategy in castration-resistant prostate cancer
-
Baylot V, Katsogiannou M, Andrieu C, Taieb D, Acunzo J, Giusiano S, Fazli L, Gleave M, Garrido C and Rocchi P: Targeting TCTP as a new therapeutic strategy in castration-resistant prostate cancer. Mol Ther 20: 2244-2256, 2012.
-
(2012)
Mol Ther
, vol.20
, pp. 2244-2256
-
-
Baylot, V.1
Katsogiannou, M.2
Andrieu, C.3
Taieb, D.4
Acunzo, J.5
Giusiano, S.6
Fazli, L.7
Gleave, M.8
Garrido, C.9
Rocchi, P.10
-
14
-
-
84861583385
-
Effect of the heat-shock protein HSP27 on androgen receptor expression and function in prostate cancer cells
-
Stope MB, Schubert T, Staar D, Rönnau C, Streitbörger A, Kroeger N, Kubisch C, Zimmermann U, Walther R and Burchardt M: Effect of the heat-shock protein HSP27 on androgen receptor expression and function in prostate cancer cells. World J Urol 30: 327-331, 2012.
-
(2012)
World J Urol
, vol.30
, pp. 327-331
-
-
Stope, M.B.1
Schubert, T.2
Staar, D.3
Rönnau, C.4
Streitbörger, A.5
Kroeger, N.6
Kubisch, C.7
Zimmermann, U.8
Walther, R.9
Burchardt, M.10
-
15
-
-
85081802841
-
-
Under review
-
Stope MB, Weiss M, Stender C, Preuß M, Peters S, Schubert T, Streitbörger A, Rönnau C, Ziegler P, Ritter CA, Kroeger N, Zimmermann U, Walther R and Burchardt M: Chemoresistance in prostate cancer is initiated by phosphorylation of the heat shock protein HSP27 and subsequent suppression of microRNA miR-1: Under review, 2013.
-
(2013)
Chemoresistance in Prostate Cancer Is Initiated by Phosphorylation of the Heat Shock Protein HSP27 and Subsequent Suppression of MicroRNA MiR-1
-
-
Stope, M.B.1
Weiss, M.2
Stender, C.3
Preuß, M.4
Peters, S.5
Schubert, T.6
Streitbörger, A.7
Rönnau, C.8
Ziegler, P.9
Ritter, C.A.10
Kroeger, N.11
Zimmermann, U.12
Walther, R.13
Burchardt, M.14
-
16
-
-
0032771030
-
A new human prostate carcinoma cell line, 22Rv1
-
Sramkoski RM, Pretlow, T G 2nd, Giaconia JM, Pretlow TP, Schwartz S, Sy MS, Marengo SR, Rhim JS, Zhang D and Jacobberger JW: A new human prostate carcinoma cell line, 22Rv1. In Vitro Cell Dev Biol Anim 35: 403-409, 1999.
-
(1999)
In Vitro Cell Dev Biol Anim
, vol.35
, pp. 403-409
-
-
Sramkoski, R.M.1
Pretlow II, T.G.2
Giaconia, J.M.3
Pretlow, T.P.4
Schwartz, S.5
Sy, M.S.6
Marengo, S.R.7
Rhim, J.S.8
Zhang, D.9
Jacobberger, J.W.10
-
17
-
-
0037112372
-
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line
-
Tepper CG, Boucher DL, Ryan PE, Ma A, Xia L, Lee L, Pretlow TG and Kung H: Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res 62: 6606-6614, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 6606-6614
-
-
Tepper, C.G.1
Boucher, D.L.2
Ryan, P.E.3
Ma, A.4
Xia, L.5
Lee, L.6
Pretlow, T.G.7
Kung, H.8
-
18
-
-
0025045495
-
Androgen receptor gene expression in human prostate carcinoma cell lines
-
Tilley WD, Wilson CM, Marcelli M and McPhaul MJ: Androgen receptor gene expression in human prostate carcinoma cell lines. Cancer Res 50: 5382-5386, 1990.
-
(1990)
Cancer Res
, vol.50
, pp. 5382-5386
-
-
Tilley, W.D.1
Wilson, C.M.2
Marcelli, M.3
McPhaul, M.J.4
-
19
-
-
84876420606
-
The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer
-
Ischia J, Saad F and Gleave M: The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer. Curr Opin Urol 23: 194-200, 2013.
-
(2013)
Curr Opin Urol
, vol.23
, pp. 194-200
-
-
Ischia, J.1
Saad, F.2
Gleave, M.3
-
20
-
-
4644237335
-
Heat-shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer
-
Rocchi P, So A, Kojima S, Signaevsky M, Beraldi E, Fazli L, Hurtado-Coll A, Yamanaka K and Gleave M: Heat-shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer. Cancer Res 64: 6595-6602, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 6595-6602
-
-
Rocchi, P.1
So, A.2
Kojima, S.3
Signaevsky, M.4
Beraldi, E.5
Fazli, L.6
Hurtado-Coll, A.7
Yamanaka, K.8
Gleave, M.9
-
21
-
-
84879628727
-
An androgen receptor N-terminal domain antagonist for treating prostate cancer
-
Myung J, Banuelos CA, Fernandez JG, Mawji NR, Wang J, Tien AH, Yang YC, Tavakoli I, Haile S, Watt K, McEwan IJ, Plymate S, Andersen RJ and Sadar MD: An androgen receptor N-terminal domain antagonist for treating prostate cancer. J Clin Invest 123: 2948-2960, 2013.
-
(2013)
J Clin Invest
, vol.123
, pp. 2948-2960
-
-
Myung, J.1
Banuelos, C.A.2
Fernandez, J.G.3
Mawji, N.R.4
Wang, J.5
Tien, A.H.6
Yang, Y.C.7
Tavakoli, I.8
Haile, S.9
Watt, K.10
McEwan, I.J.11
Plymate, S.12
Andersen, R.J.13
Sadar, M.D.14
|