Water-insoluble fraction of airborne particulate matter (PM10) induces oxidative stress in human lung epithelial A549 cells

Environmental Toxicology

Volumn 29, Issue 2, 2014, Pages 226-233

  Yi, Shuo ^a   Zhang, Fang ^a   Qu, Fang ^a   Ding, Wenjun ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Apoptosis; Cytotoxicity; DNA damage; Lung epithelial cells; Oxidative stress; PM10

Indexed keywords

AERODYNAMIC DIAMETERS; AIRBORNE PARTICULATE MATTERS; APOPTOTIC CELL DEATH; DNA DAMAGES; INTRACELLULAR LEVELS; LUNG EPITHELIAL CELLS; OXIDATIVE DNA DAMAGE; WATER SOLUBLE FRACTION;

CELL DEATH; CYTOTOXICITY; DNA; HEALTH HAZARDS; INDUCTIVELY COUPLED PLASMA; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; RESPIRATORY SYSTEM;

OXIDATIVE STRESS;

CATALASE; HYDROGEN PEROXIDE; IRON;

APOPTOSIS; CANCER; CELL ORGANELLE; OXIDATION; PARTICULATE MATTER; POLLUTION EFFECT; POLLUTION EXPOSURE; PUBLIC HEALTH; SOLUBILIZATION;

AIRBORNE PARTICLE; AMBIENT AIR; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CATALYST; CELL LEVEL; CELL STRAIN A549; CELL VIABILITY; CHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DNA DAMAGE; ENZYME ASSAY; ENZYME REPRESSION; FENTON REACTION; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; MASS SPECTROMETRY; MTT ASSAY; OXIDATIVE STRESS; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; SOLUBILITY;

APOPTOSIS; CYTOTOXICITY; DNA DAMAGE; LUNG EPITHELIAL CELLS; OXIDATIVE STRESS; PM10;

AIR POLLUTANTS; APOPTOSIS; CATALASE; CELL LINE, TUMOR; CELL SURVIVAL; EPITHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; LUNG; METALS, HEAVY; OXIDATIVE STRESS; PARTICULATE MATTER; SOLUBILITY; SUPEROXIDE DISMUTASE; SUPEROXIDES; WATER;

EID: 84891347083     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21750     Document Type: Article

References (33)

1. Ahamed M, Akhtar MJ, Siddiqui MA, Ahmad J, Musarrat J, Al-Khedhairy AA, Alsalhi MS, Alrokayan SA.2011.Oxidative stress mediated apoptosis induced by nickel ferrite nanoparticles in cultured A549 cells.Toxicology283:101-108.
2. Benhusein GM, Mutch E, Aburawi S, Williams FM.2010.Genotoxic effect induced by hydrogen peroxide in human hepatoma cells using comet assay.Libyan J Med5:4637-4642.
3. Brigelius-Flohe R.2009.Commentary: Oxidative stress reconsidered.Genes Nutr4:161-163.
4. Calcabrini A, Meschini S, Marra M, Falzano L, Colone M, De Berardis B, Paoletti L, Arancia G, Fiorentini C.2004.Fine environmental particulate engenders alterations in human lung epithelial A549 cells.Environ Res95:82-91.
5. Chirino YI, Sánchez-Pérez Y, Osornio-Vargas AR, Morales-Bárcenas R, Gutiérrez-Ruíz MC, Segura-García Y, Rosas I, Pedraza-Chaverri J, García-Cuellar CM.2010.PM(10) impairs the antioxidant defense system and exacerbates oxidative stress driven cell death.Toxicol Lett193:209-216.
6. Collins A.1999.Oxidative DNA damage, antioxidiants, and cancer.Bioessays21:238-246.
7. de Kok TM, Driece HA, Hogervorst JG, Briede JJ.2006.Toxicological assessment of ambient and traffic-related particulate matter: A review of recent studies.Mutation Res613:103-122.
8. Donaldson K, Stone V, Borm PJ, Jimenez LA, Gilmour PS, Schins RP, Knaapen AM, Rahman I, Faux SP, Brown DM, MacNee W.2003.Oxidative stress and calcium signaling in the adverse effects of environmental particles PM(10).Free Radical Biol Med34:1369-1382.
9. Dumont A, Hehner SP, Hofmann TG, Ueffing M, Droge W, Schmitz ML.1999.Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.Oncogene18:747-757.
10. Ejchart A, Sadlej-Sosnowska N.2003.Statistical evaluation and comparison of comet assay results.Mutat Res534:85-92.
11. Fridovich I.1986.Biological effects of the superoxide radical.Arch Biochem Biophys247:1-11.
12. Gazzano E, Turci F, Foresti E, Putzu MG, Aldieri E, Silvagno F, Lesci IG, Tomatis M, Rigan C, Romano C, Fubini B, Roveri N, Ghigo D.2007.Iron-loaded synthetic chrysotile: A new model solid for studying the role of iron in asbestos toxicity.Chem Res Toxicol20:380-387.
13. Ghio AJ, Devlin RB.2001.Inflammatory lung injury after bronchial instillation of air pollution particles.Am J Respiratory Crit Care Med164:704-708.
14. Imrich A, Ning Y, Kobzik L.2000.Insoluble components of concentrated air particles mediate alveolar macrophage responses in vitro.Toxicol Appl Pharmacol167:140-150.
15. Knaapen AM, Shi T, Borm PJ, Schins RP.2002.Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter.Mol Cell Biochem234-235:317-326.
16. Kusov YY, Kalinchuk NA.1978.Automated Lowry method for microdetermination of protein in samples and effluents containing nonionic detergents.Anal Biochem88:256-262.
17. Li N, Xia T, Nel A.2008.The role of oxidative stress in ambient particulate matterinduced lung diseases and its implications in the toxicity of engineered nanoparticles.Free Radical Biol Med44:1689-1699.
18. Marcazzan GM, Ceriani M, Valli G, Vecchi R.2003.Source apportionment of PM10 and PM2.5 in Milan (Italy) using receptor modelling.Sci Total Environ317(1-3):137-147.
19. McKelvey-Martin VJ, Green MH, Schmezer P, Pool-Zobel BL, De Meo MP, Collins A.1993.The single cell gel electrophoresis assay (comet assay): A European review.Mutat Res288:47-63.
20. Mosmann T.1983.Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays.J Immunol Methods65:55-63.
21. Mroz RM, Schins RP, Li H, Jimenez LA, Drost EM, Holownia A, MacNee W, Donaldson K.2008.Nanoparticle-driven DNA damage mimics irradiation-related carcinogenesis pathways.Eur Respir J31:241-251.
22. Namiecinski M, Pulaski L, Kochman A, Skolimowski J, Bartosz G, Metodiewa D.2004.Cytotoxicity, cytoprotection and neurotoxicity of novel deprenyl-related propargylamines, stable nitroxide free radicals, in vitro and in vivo.In Vivo18:171-180.
23. Olive PL, Banáth JB, Durand RE.1990.Heterogeneity in radiation induced DNA damage and repair in tumor and normal cells measured using the comet assay.Radiational Res122:86-94.
24. Ozben T.2007.Oxidative stress and apoptosis: impact on cancer therapy.J Pharm Sci96:2181-2196.
25. Pamplona P, Costantini D.2011.Molecular and structural antioxidant defenses against oxidative stress in animals.Am J Physiol Regul Integr Comp Physiol301:R843-R863.
26. Paz-Elizur T, Sevilya Z, Leitner-Dagan Y, Elinger Y, Roisman LC, Livneh Z.2008.DNA repair of oxidative DNA damage in human carcinogenesis: Potential application for cancer risk assessment and prevention.Cancer Lett266:60-72.
27. Polichetti G, Cocco S, Spinali A, Trimarco V, Nunziata A.2009.Effects of particulate matter (PM(10), PM(2.5) and PM(1)) on the cardiovascular system.Toxicology261:1-8.
28. Risom L, Mller P, Loft S.2005.Oxidative stress-induced DNA damage by particulate air pollution.Mutat Res592:119-137.
29. Soto KF, Murr LE, Garza KM.2008.Cytotoxic responses and potential respiratory health effects of carbon and carbonaceous nanoparticulates in the Paso del Norte airshed environment.Int J Environ Res Public Health5:12-25.
30. Sun G, Crissman K, Norwood J, Richards J, Slade R, Hatch GE.2001.Oxidative interactions of synthetic lung epithelial lining fluid with metal-containing particulate matter. Am J Physiol.Lung Cell Mol Physiol281:L807-L815.
31. Valavanidis A, Fiotakis K, Vlachogianni T.2008.Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms.J Environ Sci Health C Environ Carcinog Ecotoxicol Rev26:339-362.
32. Vollgraf U, Wegner M, Richter-Landsberg C.1999.Activation of AP-1 and nuclear factor-kappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes.J Neurochem73:2501-2509.
33. Wei H, Wei D, Yi S, Zhang F, Ding W.2010.Oxidative stress induced by urban fine particles in cultured EA.hy926 cells.Hum Exp Toxicol30:579-590.