A new hemodynamic model shows that temporal perturbations of cerebral blood flow and metabolic rate of oxygen cannot be measured individually using functional near-infrared spectroscopy

Physiological Measurement

Volumn 35, Issue 1, 2014, Pages

  Fantini, Sergio ^a  

^a Tufts University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; BLOOD VESSELS; INFRARED DEVICES; METABOLISM; NEAR INFRARED SPECTROSCOPY; OXYGEN; PARAMETER ESTIMATION; PHYSIOLOGICAL MODELS;

BLOOD FLOW; BLOOD VOLUMES; BLOOD-FLOW RATES; CEREBRAL BLOOD FLOW; DYNAMICS MODELS; FUNCTIONAL NEAR INFRARED SPECTROSCOPY; HEMODYNAMIC MODELLING; METABOLIC RATES; SPECTROSCOPY MEASUREMENTS; TEMPORAL PERTURBATIONS;

HEMODYNAMICS;

OXYGEN;

ARTICLE; BIOLOGICAL MODEL; BRAIN; BRAIN CIRCULATION; HEMODYNAMICS; KINETICS; METABOLISM; NEAR INFRARED SPECTROSCOPY; VASCULARIZATION;

BRAIN; CEREBROVASCULAR CIRCULATION; HEMODYNAMICS; KINETICS; MODELS, BIOLOGICAL; OXYGEN; SPECTROSCOPY, NEAR-INFRARED;

EID: 84891308586     PISSN: 09673334     EISSN: 13616579     Source Type: Journal    
DOI: 10.1088/0967-3334/35/1/N1     Document Type: Article

References (17)

1. Boas D A, Strangman G, Culver J P, Hoge R D, Jasdzewski G, Poldrack R A, Rosen B R and Mandeville J B 2003 Can the cerebral metabolic rate of oxygen be measured with near-infrared spectroscopy? Phys. Med. Biol. 48 2405-18
2. Chen J L, Wei L, Acuff V, Bereczki D, Hans F J, Otsuka T, Finnegan W, Patlak C and Fenstermacher J 1994 Slightly altered permeability-surface area products imply some cerebral capillary recruitment during hypercapnia Microvasc. Res. 48 190-211
3. Dunn A K, Devor A, Dale A M and Boas D A 2005 Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex NeuroImage 27 279-90
4. Durduran T and Yodh A G 2014 Diffuse correlation spectroscopy for non-invasive, micro-vascular cerebral blood flow measurement NeuroImage 85 51-63
5. Fantini S 2002 A haemodynamic model for the physiological interpretation of in vivo measurements of the concentration and oxygen saturation of haemoglobin Phys. Med. Biol. 47 N249-57
6. Fantini S 2014 Dynamic model for the tissue concentration and oxygen saturation of hemoglobin in relation to blood volume, flow velocity, and oxygen consumption: implications for functional neuroimaging and coherent hemodynamics spectroscopy (CHS) NeuroImage 85 202-21
7. Ferrari M and Quaresima V 2012 A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application NeuroImage 63 921-35
8. Göbel U, Klein B, Schrock H and Kuschinsky W 1989 Lack of capillary recruitment in the brains of awake rats during hypercapnia J. Cereb. Blood Flow Metab. 9 491-9
9. Hoge R D, Atkinson J, Gill B, Crelier G R, Marrett S and Pike G B 1999 Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model Magn. Res. Med. 42 849-63
10. Jones M, Berwick J, Johnston D and Mayhew J 2001 Concurrent optical imaging spectroscopy and laser-Doppler flowmetry: the relationship between blood flow, oxygenation, and volume in rodent barrel cortex NeuroImage 13 1002-15
11. Kida I, Rothman D L and Hyder F 2007 Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration J. Cereb. Blood Flow Metab. 27 690-6
12. Kuschinsky W and Paulson O B 1992 Capillary circulation in the brain Cerebrovasc. Brain Metab. Rev. 4 261-86
13. Mayhew J, Johnston D, Berwick J, Jones M, Coffey P and Zheng Y 2001 Erratum and addendum: Spectroscopic analysis of neural activaty in the brain: Increased oxygen consumption following activation of barrel cortex NeuroImage 13 540-3
14. Roche-Labarbe N, Fenoglio A, Radhakrishnan H, Kocienski-Filip M, Carp S A, Dubb J, Boas D A, Grant E and Franceschini M A 2014 Somatosensory evoked changes in cerebral oxygen consumption measured non-invasively in premature neonates NeuroImage 85 279-86
15. Villringer A 2012 The intravascular susceptibility effect and the underlying physiology of fMRI NeuroImage 62 995-9
16. Villringer A, Them A, Lindauer U, Einhäupl K and Dirnagl U 1994 Capillary perfusion of the rat brain cortex. An in vivo confocal microscopy study Circ. Res. 75 55-62
17. Zoccoli G, Lucchi M L, Andreoli E, Bach V, Cianci T, Lenzi P and Franzini C 1996 Brain capillary perfusion during sleep J. Cereb. Blood Flow Metab. 16 1312-8