Clonal dissemination of Klebsiella pneumoniae ST512 carrying blaKPC-3 in a hospital in southern Italy

APMIS

Volumn 122, Issue 1, 2014, Pages 42-46

  Pulcrano, Giovanna ^a   Iula, Dora Vita ^a   de Luca, Cristiana ^a   Roscetto, Emanuela ^a   Vollaro, Antonio ^a   Rossano, Fabio ^a   Catania, Maria Rosaria ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

BlaKPC 3; BlaTEM; Klebsiella pneumoniae ST512; Multidrug resistance; Outbreak

Indexed keywords

BETA LACTAMASE SHV; CARBAPENEMASE; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; COTRIMOXAZOLE; ERTAPENEM; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TIGECYCLINE;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATION; BLA KPC3 BACTERIAL GENE; BLA SVH BACTERIAL GENE; BLA TEM BACTERIAL GENE; BLOOD CULTURE; CATHETER; CELL SPREADING; CLONAL SPECIES; CONTROLLED STUDY; ENZYME SYNTHESIS; EPSILOMETER TEST; HOSPITAL ADMISSION; ITALY; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SPUTUM CULTURE; THROAT CULTURE; URINE CULTURE;

EID: 84891153127     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/apm.12097     Document Type: Article

References (15)

1. Arnold RS, Thom KA, Sharma S, Phillips M, Kristie Johnson J. Emergence of Klebsiella pneumoniae carbapenemase-producing bacteria. South Med J 2011;104:40-5.
2. Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, et al. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother 2001;45:1151-61.
3. Giani T, D'Andrea MM, Pecile P, Borgianni L, Nicoletti P, Tonelli F, et al. Emergence in Italy of Klebsiella pneumoniae sequence type 258 producing KPC-3 Carbapenemase. J Clin Microbiol 2009;47:3793-4.
4. Mammina C, Palma DM, Bonura C, Anna Plano MR, Monastero R, Sodano C, et al. Outbreak of infection with Klebsiella pneumoniae sequence type 258 producing Klebsiella pneumoniae Carbapenemase 3 in an intensive care unit in Italy. J Clin Microbiol 2010;48:1506-7.
5. Fontana C, Favaro M, Sarmati L, Natoli S, Altieri A, Bossa MC, et al. Emergence of KPC-producing Klebsiella pneumoniae in Italy. BMC Res Notes 2010;3:40.
6. Gupta N, Limbago BM, Patel JB, Kallen AJ. Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. Clin Infect Dis 2011;53:60-7.
7. Warburg G, Hidalgo-Grass C, Partridge SR, Tolmasky ME, Temper V, Moses AE, et al. A carbapenem-resistant Klebsiella pneumoniae epidemic clone in Jerusalem: sequence type 512 carrying a plasmid encoding aac(6')-Ib. J Antimicrob Chemother 2012;67:898-901.
8. European Committee on Antimicrobial Susceptibility Testing. Breakpoint, Tables for Interpretation of MICs and Zone Diameters, Version 13. Basel: EUCAST, 2011.
9. Dallenne C, Da Costa A, Decré D, Favier C, Arlet G. Development of a set of multiplex PCR assays for the detection of genes encoding important beta-lactamases in Enterobacteriaceae. J Antimicrob Chemother 2010;65:490-5.
10. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233-9.
11. Leavitt A, Chmelnitsky I, Ofek I, Carmeli Y, Navon-Venezia S. Plasmid pKpQIL encoding KPC-3 and TEM-1 confers carbapenem resistance in an extremely drug-resistant epidemic Klebsiella pneumoniae strain. J Antimicrob Chemother 2010;65:243-8.
12. Benenson S, Warburg G, Hidalgo-Grass C, Temper V, Moses AE, Block C, et al. Comparison of two carbapenem-resistant Klebsiella pneumoniae clones: from a contained outbreak in a paediatric population and from a national epidemic. J Antimicrob Chemother 2012;67:1651-4.
13. Mezzatesta ML, Gona F, Caio C, Petrolito V, Sciortino D, Sciacca A, et al. Outbreak of KPC-3-producing, and colistin-resistant, Klebsiella pneumoniae infections in two Sicilian hospitals. Clin Microbiol Infect 2011;17:1444-7.
14. Giakkoupi P, Papagiannitsis CC, Miriagou V, Pappa O, Polemis M, Tryfinopoulou K, et al. An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009-10). J Antimicrob Chemother 2011;66:1510-3.
15. Mavroidi A, Miriagou V, Malli E, Stefos A, Dalekos GN, Tzouvelekis LS, et al. Emergence of Escherichia coli sequence type 410 (ST410) with KPC-2 β-lactamase. Int J Antimicrob Agents 2012;39:247-50.