Priming of mononuclear cells with a combination of growth factors enhances wound healing via high angiogenic and engraftment capabilities

Journal of Cellular and Molecular Medicine

Volumn 17, Issue 12, 2013, Pages 1644-1651

  Jin, Enze ^a   Kim, Jong Min ^b   Kim, Sung Whan ^a,c  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Dong A University   (South Korea)

^c Dong A University College of Medicine   (South Korea)

Author keywords

Growth factor; Mononuclear cell; Transplantation; Wound healing

Indexed keywords

MUS;

GROWTH FACTOR; SIGNAL PEPTIDE;

ANGIOGENESIS; ANIMAL; APOPTOSIS; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECT; HUMAN; MALE; METABOLISM; MONONUCLEAR CELL; MOUSE; NONOBESE DIABETIC MOUSE; PATHOLOGY; SCID MOUSE; TRANSPLANTATION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WOUND HEALING;

GROWTH FACTOR; MONONUCLEAR CELL; TRANSPLANTATION; WOUND HEALING;

ANIMALS; APOPTOSIS; CELL ADHESION; CELL DIFFERENTIATION; CULTURE MEDIA; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICE, INBRED NOD; MICE, SCID; NEOVASCULARIZATION, PHYSIOLOGIC; UP-REGULATION; WOUND HEALING;

EID: 84891142442     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12152     Document Type: Article

References (26)

1. Falanga V. Wound healing and its impairment in the diabetic foot. Lancet. 2005; 366: 1736-43.
2. Martin P. Wound healing-aiming for perfect skin regeneration. Science. 1997; 276: 75-81.
3. Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006; 8: 315-7.
4. Moulik PK, Mtonga R, Gill GV. Amputation and mortality in new-onset diabetic foot ulcers stratified by etiology. Diabetes Care. 2003; 26: 491-4.
5. Byun KH, Kim SW. Is stem cell-based therapy going on or out for cardiac disease? Korean Circ J. 2009; 39: 87-92.
6. Shake JG, Gruber PJ, Baumgartner WA, et al. Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Ann Thorac Surg. 2002; 73: 1919-25; discussion 26.
7. Tomar AS, Banerjee A, Hazari K, et al. Anaesthetic considerations for noncoronary surgery on a perfused beating heart under cardiopulmonary bypass. Ann Card Anaesth. 2002; 5: 59-62.
8. Wu Y, Chen L, Scott PG, et al. Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells. 2007; 25: 2648-59.
9. Fernandez Pujol B, Lucibello FC, Gehling UM, et al. Endothelial-like cells derived from human CD14 positive monocytes. Differentiation. 2000; 65: 287-300.
10. + monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. J Leukoc Biol. 2003; 74: 833-45.
11. Zhao Y, Glesne D, Huberman E. A human peripheral blood monocyte-derived subset acts as pluripotent stem cells. Proc Natl Acad Sci USA. 2003; 100: 2426-31.
12. Medina A, Brown E, Carr N, et al. Circulating monocytes have the capacity to be transdifferentiated into keratinocyte-like cells. Wound Repair Regen. 2009; 17: 268-77.
13. Kim MH, Zhang HZ, Kim SW. Combined growth factors enhanced angiogenic potential of cord blood-derived mononuclear cells transplanted to ischemic limbs. J Mol Cell Cardiol. 2011; 51: 702-12.
14. + cells have robust angiogenic and vasculogenic properties and are effective for treating ischemic vascular disease. J Am Coll Cardiol. 2010; 56: 593-607.
15. Cho HJ, Lee N, Lee JY, et al. Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heart. J Exp Med. 2007; 204: 3257-69.
16. Kim MH, Jin E, Zhang HZ, et al. Robust angiogenic properties of cultured human peripheral blood-derived CD31(+) cells. Int J Cardiol. 2013; 166: 709-15.
17. Zhang C, Fu L, Fu J, et al. Fibroblast growth factor receptor 2-positive fibroblasts provide a suitable microenvironment for tumor development and progression in esophageal carcinoma. Clin Cancer Res. 2009; 15: 4017-27.
18. Kim SW, Zhang HZ, Guo L, et al. Amniotic mesenchymal stem cells enhance wound healing in diabetic NOD/SCID mice through high angiogenic and engraftment capabilities. PLoS ONE. 2012; 7: e41105.
19. Ii M, Takenaka H, Asai J, et al. Endothelial progenitor thrombospondin-1 mediates diabetes-induced delay in reendothelialization following arterial injury. Circ Res. 2006; 98: 697-704.
20. Kofidis T, de Bruin JL, Yamane T, et al. Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration. Stem Cells. 2004; 22: 1239-45.
21. Price JT, Wilson HM, Haites NE. Epidermal growth factor (EGF) increases the in vitro invasion, motility and adhesion interactions of the primary renal carcinoma cell line, A704. Eur J Cancer. 1996; 32A: 1977-82.
22. Parrizas M, Saltiel AR, LeRoith D. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways. J Biol Chem. 1997; 272: 154-61.
23. Chae JK, Kim I, Lim ST, et al. Coadministration of angiopoietin-1 and vascular endothelial growth factor enhances collateral vascularization. Arterioscler Thromb Vasc Biol. 2000; 20: 2573-8.
24. Papapetropoulos A, Fulton D, Mahboubi K, et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J Biol Chem. 2000; 275: 9102-5.
25. Kim SW, Lee DW, Yu LH, et al. Mesenchymal stem cells overexpressing GCP-2 improve heart function through enhanced angiogenic properties in a myocardial infarction model. Cardiovasc Res. 2012; 95: 495-506.
26. Tuschil A, Lam C, Haslberger A, et al. Interleukin-8 stimulates calcium transients and promotes epidermal cell proliferation. J Invest Dermatol. 1992; 99: 294-8.