Basics and principles for building natural product-based libraries for HTS

Chemical Genomics

Volumn , Issue , 2012, Pages 87-98

  Quinn, Ronald J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84891129784     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9781139021500.010     Document Type: Chapter

References (20)

1. Camp, D., and Quinn, R. J. (2007). The evolution of com-pound libraries for applied and basic research. ChemAust 74, 14-16.
2. Williams, J., Read, C., Norton, A., Burgman, M., Proctor, W., and Andeerson, H. (2001). Biodiversity, Australia State Of The Environment Report 2001 (Theme Report) (Canberra: CSIRO Publishing on behalf of the Department of the Environment and Heritage).
3. Eldridge, G. R., Veroort, H. C., Lee, C. M., Cremin, P. A., Williams, C. T., Hart, S. M., Goering, M. G., O'Neil-Johnson, M., and Zeng, L. (2002). High-throughput method for the production and analysis of large natural product libraries for drug discovery. Anal Chem 74, 3963-3971.
4. Strege, M. A. (1999). High-performance liquid chromatographic-electrospray ionization mass spectro-metric analyses for the integration of natural products with modern high-throughput screening. J Chromatogr B 725, 67-68.
5. Wolf, D., and Siems, K. (2007). Burning the hay to find the needle-data mining strategies in natural product dereplication. Chimia 61, 339-345.
6. Julian R. K., Jr., Higgs, R. E., Gygi, J. D., and Hilton, M. D. (1998). A method for quantitatively differentiating crude natural extracts using high-performance liquid chromatography-electrospray mass spectrometry. Anal Chem 70, 3249-3254.
7. Bitzer, J., Kopcke, B., Stadler, M., Helwig, V., Ju, Y.-M., Seip, S., andHenkel, T. (2007). Accelerated dereplicationofnatural products, supported by reference libraries. Chimia 61, 332-338.
8. Schroeder, F. C., Gibson, D. M., Churchill, A. C. L., Sojikul, P., Wursthorn, E. J., Krasnoff, S. B., and Clardy, J. (2007). Differential analysis of 2D NMR spectra: New natural prod-ucts from a pilot-scale fungal extract library. Angew Chem Int Ed46, 901-904.
9. Schroeder, F. C. Dictionary of Natural Products on CD-Rom (2005). (London:. Chapman and Hall/CRC Press). www.crcpress.com.
10. Quinn, R. J., Carroll, A. R., Pham, N. B., Baron, P., Palfra-man, M. E., Suraweera, L., Pierens, G. K., and Muresan, S. (2008). Developing a drug-like natural product library. JNat Prod 71, 464-468.
11. Lee, M. L., and Schneider, G. (2001). Scaffold architecture and pharmacophoric properties of natural products and trade drugs: Application in the design ofnatural product-based combinatorial libraries. J Comb Chem 3, 284-289.
12. Harrigan, G. G., and Goetz, G. H. (2005). Chemical and biological integrity in natural products screening. Comb Chem High Throughput Screen 8, 529-534.
13. Bindseil, K. U., Jakupovic, J., Wolf, D., Lavayre, J., Leboul, J., and Van Der Pyl, D. (2001). Pure compound libraries; a new perspective for natural product based drug discovery. Drug Discov Today 6, 840-847.
14. Abel, U., Koch, C., Speitling, M., and Hansske, F. G. (2002). Modern methods to produce natural-product libraries. Curr Opin Chem Biol 6, 453-458.
15. Appleton, D. R., Buss, A. D., and Butler, M. S. (2007). A simple method for high-throughput extract prefractionation for biological screening. Chimia 61, 327-331.
16. Schmid, I., Sattler, I., Grabley, S., and Thiericke, R. (1999). Natural products in high throughput screening: Automated high-quality sample preparation. J Biomol Screen 4, 15-25.
17. Jia, Q. (2003). Generating and screening a natural product library for cyclooxygenase and lipoxygenase dual inhibitors. Stud Nat Prod Chem 29, 643-718.
18. Wagenaar, M. M. (2008). Pre-fractionated microbial samples-the second generation natural products library at Wyeth. Molecules 13, 1406-1426.
19. Bugni, T. S., Richards, B., Bhoite, L., Cimbora, C., Harper, M. K., and Ireland, C. M. (2008). Marine natural product libraries for high-throughput screening and rapid drug discovery. J Nat Prod.71, 1095-1098.
20. McArdle, B. M., Campitelli, M. R., and Quinn, R. J. (2006). A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. J Nat Prod 69, 14-17.