Population pharmacokinetic and pharmacogenetic analysis of tacrolimus in paediatric liver transplant patients

British Journal of Clinical Pharmacology

Volumn 77, Issue 1, 2014, Pages 130-140

  Abdel Jalil, Mariam H ^a   Hawwa, Ahmed F ^a   McKiernan, Patrick J ^b   Shields, Michael D ^a   McElnay, James C ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b BIRMINGHAM CHILDREN S HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

gene polymorphisms; liver transplant; nonmem; paediatrics; population pharmacokinetics; tacrolimus

Indexed keywords

TACROLIMUS; ABCB1 PROTEIN, HUMAN; CYP3A5 PROTEIN, HUMAN; CYTOCHROME P450 3A; IMMUNOSUPPRESSIVE AGENT; MULTIDRUG RESISTANCE PROTEIN;

ALLELE; ARTICLE; CHILD; CLINICAL ARTICLE; CYP3A5 GENE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG MONITORING; FEMALE; GENOTYPE; HUMAN; LIVER TRANSPLANTATION; MALE; NEPHROTOXICITY; PHARMACOGENETICS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; BIOLOGICAL MODEL; CHEMICALLY INDUCED; GENETICS; GRAFT RECIPIENT; GRAFT REJECTION; INFANT; KIDNEY DISEASE; PRESCHOOL CHILD; RETROSPECTIVE STUDY;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CYTOCHROME P-450 CYP3A; FEMALE; GENOTYPE; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; KIDNEY DISEASES; LIVER TRANSPLANTATION; MALE; MODELS, BIOLOGICAL; P-GLYCOPROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; TACROLIMUS; TRANSPLANT RECIPIENTS;

EID: 84891045107     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12174     Document Type: Article

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