Gestational vitamin A deficiency: A novel cause of sensorineural hearing loss in the developing world?

Medical Hypotheses

Volumn 82, Issue 1, 2014, Pages 6-10

  Emmett, Susan D ^a,b   West, Keith P ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 3; LIVER ENZYME; PLACEBO; RETINAL DEHYDROGENASE; RETINOIC ACID RECEPTOR; RETINOL; TRANSFORMING GROWTH FACTOR;

ARTICLE; BIRTH DEFECT; BRAIN DEVELOPMENT; DISEASE SEVERITY; DOSE RESPONSE; EAR INFECTION; ENZYME DEFECT; FETUS DEVELOPMENT; FOLLOW UP; GESTATIONAL AGE; HUMAN; IN VIVO STUDY; INNER EAR MALFORMATION; LUNG DEVELOPMENT; NONHUMAN; OTITIS MEDIA; PERCEPTION DEAFNESS; RETINOL DEFICIENCY; SYNTHESIS;

ANIMALIA;

DEVELOPING COUNTRIES; DIETARY SUPPLEMENTS; EAR, INNER; FEMALE; HEARING LOSS, SENSORINEURAL; HUMANS; MODELS, BIOLOGICAL; PREGNANCY; TRETINOIN; VITAMIN A; VITAMIN A DEFICIENCY;

EID: 84890881569     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2013.09.028     Document Type: Article

References (56)

1. World Health Organization. Deafness and hearing loss, 2013 [accessed 16.07.2013]. http://www.who.int/mediacentre/factsheets/fs300/en.
2. Olusanya B.O., Ruben R.J., Parving A. Reducing the burden of communication disorders in the developing world: an opportunity for the millennium development project. JAMA 2006, 296(4):441-444.
3. Ruben R.J. Redefining the survival of the fittest: communication disorders in the 21st century. Laryngoscope 2000, 110(2 Pt 1):241-245.
4. Olusanya B.O. Addressing the global neglect of childhood hearing impairment in developing countries. PLoS Med 2007, 4(4):e74.
5. Moeller M.P. Early intervention and language development in children who are deaf and hard of hearing. Pediatrics 2000, 106(3):e43.
6. Kennedy C.R., McCann D.C., Campbell M.J., et al. Language ability after early detection of permanent childhood hearing impairment. N Engl J Med 2006, 354(20):2131-2141.
7. Olusanya B.O., Luxon L.M., Wirz S.L. Childhood deafness poses problems in developing countries. BMJ 2005, 330(7489):480-481.
8. Jung D., Bhattacharyya N. Association of hearing loss with decreased employment and income among adults in the United States. Ann Otol Rhinol Laryngol 2012, 121(12):771-775.
9. Hogan A., O'Loughlin K., Davis A., et al. Hearing loss and paid employment: Australian population survey findings. Int J Audiol 2009, 48(3):117-122.
10. World Health Organization. Global prevalence of vitamin A deficiency in populations at risk 1995-2005, 2009 [accessed 19.05.2013]. http://whqlibdoc.who.int/publications/2009/9789241598019_eng.pdf.
11. West K.P. Extent of vitamin A deficiency among preschool children and women of reproductive age. J Nutr 2002, 132(Suppl. 9):2857S-2866S.
12. Sommer A., West K.P. Vitamin a deficiency 1996, Oxford University Press, USA.
13. Singh V., West K.P. Vitamin A deficiency and xerophthalmia among school-aged children in Southeastern Asia. Eur J Clin Nutr 2004, 58(10):1342-1349.
14. West K.P., Katz J., Khatry S.K., et al. Double blind, cluster randomised trial of low dose supplementation with vitamin A or beta carotene on mortality related to pregnancy in Nepal. The NNIPS-2 study group. BMJ 1999, 318(7183):570-575.
15. Christian P., West K.P., Khatry S.K., et al. Night blindness during pregnancy and subsequent mortality among women in Nepal: effects of vitamin A and beta-carotene supplementation. Am J Epidemiol 2000, 152(6):542-547.
16. Checkley W., West K.P., Wise R.A., et al. Maternal vitamin A supplementation and lung function in offspring. N Engl J Med 2010, 362(19):1784-1794.
17. West K.P., Christian P., Labrique A.B., et al. Effects of vitamin A or beta carotene supplementation on pregnancy-related mortality and infant mortality in rural Bangladesh: a cluster randomized trial. JAMA 2011, 305(19):1986-1995.
18. Christian P., Labrique A.B., Ali H., et al. Maternal vitamin A and β-carotene supplementation and risk of bacterial vaginosis: a randomized controlled trial in rural Bangladesh. Am J Clin Nutr 2011, 94(6):1643-1649.
19. Scrimshaw N.S., Taylor C.E., Gordon J.E. Interactions of nutrition and infection 1968, World Health Organization, Geneva.
20. Manning S.C., Wright C.G. Incidence of otitis media in vitamin A-deficient guinea pigs. Otolaryngol Head Neck Surg 1992, 107(5):701-706.
21. Chole R.A. Squamous metaplasia of the middle ear mucosa during vitamin A deprivation. Otolaryngol Head Neck Surg 1979, 87(6):837-844.
22. Elemraid M.A., Mackenzie I.J., Fraser W.D., et al. Nutritional factors in the pathogenesis of ear disease in children: a systematic review. Ann Trop Paediatr 2009, 29(2):85-99.
23. Schmitz J., West K.P., Khatry S.K., et al. Vitamin A supplementation in preschool children and risk of hearing loss as adolescents and young adults in rural Nepal: randomised trial cohort follow-up study. BMJ 2012, 344:d7962.
24. Frenz D.A., Liu W., Cvekl A., et al. Retinoid signaling in inner ear development: A "Goldilocks" phenomenon. Am J Med Genet A 2010, 152A(12):2947-2961.
25. Niederreither K., Subbarayan V., Dollé P., et al. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet 1999, 21(4):444-448.
26. Niederreither K., Vermot J., Schuhbaur B., et al. Retinoic acid synthesis and hindbrain patterning in the mouse embryo. Development 2000, 127(1):75-85.
27. Maden M., Gale E., Kostetskii I., et al. Vitamin A-deficient quail embryos have half a hindbrain and other neural defects. Curr Biol 1996, 6(4):417-426.
28. Kil S.-H., Streit A., Brown S.T., et al. Distinct roles for hindbrain and paraxial mesoderm in the induction and patterning of the inner ear revealed by a study of vitamin-A-deficient quail. Dev Biol 2005, 285(1):252-271.
29. White J.C., Highland M., Kaiser M., et al. Vitamin A deficiency results in the dose-dependent acquisition of anterior character and shortening of the caudal hindbrain of the rat embryo. Dev Biol 2000, 220(2):263-284.
30. Romand R., Dollé P., Hashino E. Retinoid signaling in inner ear development. J Neurobiol 2006, 66(7):687-704.
31. Romand R., Hashino E., Dollé P., et al. The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mech Dev 2002, 119(2):213-223.
32. Romand R. The roles of retinoic acid during inner ear development. Curr Top Dev Biol 2003, 57:261-291.
33. Romand R., Kondo T., Cammas L., et al. Dynamic expression of the retinoic acid-synthesizing enzyme retinol dehydrogenase 10 (rdh10) in the developing mouse brain and sensory organs. J Comp Neurol 2008, 508(6):879-892.
34. Pittlik S., Domingues S., Meyer A., et al. Expression of zebrafish aldh1a3 (raldh3) and absence of aldh1a1 in teleosts. Gene Expr Patterns 2008, 8(3):141-147.
35. Sánchez-Guardado L.O., Ferran J.L., Mijares J., et al. Raldh3 gene expression pattern in the developing chicken inner ear. J Comp Neurol 2009, 514(1):49-65.
36. McCaffery P., Dräger U.C. Regulation of retinoic acid signaling in the embryonic nervous system: a master differentiation factor. Cytokine Growth Factor Rev 2000, 11(3):233-249.
37. Romand R., Kondo T., Fraulob V., et al. Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear. J Comp Neurol 2006, 496(5):643-654.
38. Alvarez Y., Alonso M.T., Vendrell V., et al. Requirements for FGF3 and FGF10 during inner ear formation. Development 2003, 130(25):6329-6338.
39. Liu W., Levi G., Shanske A., et al. Retinoic acid-induced inner ear teratogenesis caused by defective Fgf3/Fgf10-dependent Dlx5 signaling. Birth Defects Res B Dev Reprod Toxicol 2008, 83(2):134-144.
40. Torres M., Gómez-Pardo E., Gruss P. Pax2 contributes to inner ear patterning and optic nerve trajectory. Development 1996, 122(11):3381-3391.
41. Raz Y., Kelley M.W. Retinoic acid signaling is necessary for the development of the organ of Corti. Dev Biol 1999, 213(1):180-193.
42. Robledo R.F., Lufkin T. Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus. Genesis 2006, 44(9):425-437.
43. Acampora D., Merlo G.R., Paleari L., et al. Craniofacial, vestibular and bone defects in mice lacking the distal-less-related gene Dlx5. Development 1999, 126(17):3795-3809.
44. Tekin M., Oztürkmen Akay H., Fitoz S., et al. Homozygous FGF3 mutations result in congenital deafness with inner ear agenesis, microtia, and microdontia. Clin Genet 2008, 73(6):554-565.
45. Tekin M., Hişmi B.O., Fitoz S., et al. Homozygous mutations in fibroblast growth factor 3 are associated with a new form of syndromic deafness characterized by inner ear agenesis, microtia, and microdontia. Am J Hum Genet 2007, 80(2):338-344.
46. Wieland I., Muschke P., Jakubiczka S., et al. Refinement of the deletion in 7q21.3 associated with split hand/foot malformation type 1 and mondini dysplasia. J Med Genet 2004, 41(5):e54.
47. Crackower M.A., Scherer S.W., Rommens J.M., et al. Characterization of the split hand/split foot malformation locus SHFM1 at 7q21.3-q22.1 and analysis of a candidate gene for its expression during limb development. Hum Mol Genet 1996, 5(5):571-579.
48. Food and Nutrition Board, Institute of Medicine Vitamin A. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc 2001, National Academies Press, Washington, DC, p. 82-161.
49. Sauer T., Emmett S., West K.P. Assuring vitamin A adequacy to prevent eye and ear disorders. Carotenoids and vitamin A in translational medicine 2013, 111-122. CRC Press, Boca Raton, FL. O. Sommerburg, W. Siems, K. Kraemer (Eds.).
50. Palmer A.C. Early life nutritional exposures and long-term programming of the immune system. Unpublished doctoral dissertation 2010, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
51. Kirkwood B.R., Hurt L., Amenga-Etego S., et al. Effect of vitamin A supplementation in women of reproductive age on maternal survival in Ghana (ObaapaVitA): a cluster-randomised, placebo-controlled trial. Lancet 2010, 375(9726):1640-1649.
52. Thompson D.C., McPhillips H., Davis R.L., et al. Universal newborn hearing screening: summary of evidence. JAMA 2001, 286(16):2000-2010.
53. Olusanya B.O., Wirz S.L., Luxon L.M. Hospital-based universal newborn hearing screening for early detection of permanent congenital hearing loss in Lagos, Nigeria. Int J Pediatr Otorhinolaryngol 2008, 72(7):991-1001.
54. Tanon-Anoh M.J., Sanogo-Gone D., Kouassi K.B. Newborn hearing screening in a developing country: results of a pilot study in Abidjan, CÔte d'ivoire. Int J Pediatr Otorhinolaryngol 2010, 74(2):188-191.
55. UNICEF. State of the World's Children 2013: Children with Disabilities, 2013 [accessed 17.07.2013]. http://www.unicef.org/sowc2013/files/SWCR2013_ENG_Lo_res_24_Apr_2013.pdf.
56. Morzaria S., Westerberg B.D., Kozak F.K. Systematic review of the etiology of bilateral sensorineural hearing loss in children. Int J Pediatr Otorhinolaryngol 2004, 68(9):1193-1198.