TNFα induces the expression of genes associated with endothelial dysfunction through p38MAPK-mediated down-regulation of miR-149

Biochemical and Biophysical Research Communications

Volumn 443, Issue 1, 2014, Pages 246-251

  Palmieri, Daniela ^a   Capponi, Simona ^a   Geroldi, Alessandro ^a   Mura, Marzia ^a   Mandich, Paola ^a   Palombo, Domenico ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Endothelial dysfunction; IL 6; INOS; MicroRNA; MiR 149; MMP 9; TNF

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA; MIRNA 149; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; ZYMOGRAPHY;

ENDOTHELIAL DYSFUNCTION; IL-6; INOS; MICRORNA; MIR-149; MMP-9; TNFΑ;

CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-6; MATRIX METALLOPROTEINASE 9; MICRORNAS; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890859979     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.11.092     Document Type: Article

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