Determination of polychlorinated biphenyls and organochlorine pesticides in small volumes of human blood by high-throughput on-line SPE-LVI-GC-HRMS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 945-946, Issue , 2014, Pages 217-224

  Wittsiepe, Jürgen ^a   Nestola, Marco ^a,b   Kohne, Matthias ^a   Zinn, Peter ^a   Wilhelm, Michael ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Gas chromatography; Human blood; Large volume injection; Mass spectrometry; On line solid phase extraction; Organochlorine pesticides; Polychlorinated biphenyls

Indexed keywords

AUTOMATION; BLOOD; DRUG PRODUCTS; GAS CHROMATOGRAPHY; ISOMERS; MASS SPECTROMETRY; METABOLITES; ORGANIC POLLUTANTS; PESTICIDES; PHASE SEPARATION; POLYCHLORINATED BIPHENYLS; PROJECTILES;

DICHLORODIPHENYLTRICHLOROETHANE; HEXACHLOROCYCLOHEXANE ISOMERS; HIGH RESOLUTION MASS SPECTROMETRY; HUMAN BLOODS; LARGE VOLUME INJECTION; ON-LINE SOLID PHASE EXTRACTION; ORGANOCHLORINE PESTICIDES; POLYCHLORINATED BIPHENYL (PCBS);

EXTRACTION;

CHLORPHENOTANE; HEXACHLOROBENZENE; HEXACHLOROCYCLOHEXANE; ORGANOCHLORINE PESTICIDE; PENTACHLOROBENZENE; POLYCHLORINATED BIPHENYL;

ADSORPTION; ANALYTIC METHOD; ARTICLE; BLOOD; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HUMAN; LARGE VOLUME INJECTION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MASS SPECTROMETER; MASS SPECTROMETRY; PRECIPITATION; PRIORITY JOURNAL; REACTION TIME; SIGNAL NOISE RATIO; SOLID PHASE EXTRACTION;

GAS CHROMATOGRAPHY; HUMAN BLOOD; LARGE VOLUME INJECTION; MASS SPECTROMETRY; ON-LINE SOLID PHASE EXTRACTION; ORGANOCHLORINE PESTICIDES; POLYCHLORINATED BIPHENYLS;

EQUIPMENT DESIGN; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; HYDROCARBONS, CHLORINATED; LIMIT OF DETECTION; PESTICIDES; POLYCHLORINATED BIPHENYLS; SOLID PHASE EXTRACTION;

EID: 84890848608     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.11.059     Document Type: Article

References (27)

1. UNEP, United Nations Environment Programme Stockholm Convention on Persistent Organic Pollutants (POPs) 2009, http://www.pops.int/.
2. Govarts E., Nieuwenhuijsen M., Schoeters G., Ballester F., Bloemen K., de Boer M., Chevrier C., Eggesbo M., Guxens M., Kramer U., Legler J., Martinez D., Palkovicova L., Patelarou E., Ranft U., Rautio A., Petersen M.S., Slama R., Stigum H., Toft G., Trnovec T., Vandentorren S., Weihe P., Kuperus N.W., Wilhelm M., Wittsiepe J., Bonde J.P. Environ. Health Perspect. 2012, 120:162. OBELIX, ENRIECO.
3. Analyses of Hazardous Substances in Biological Materials, Later: Biomonitoring Methods 1985-2011, Deutsche Forschungsgemeinschaft, Weinheim. J. Angerer (Ed.).
4. Schmid K., Lederer P., Göen T., Schaller K.H., Strebl H., Weber A., Angerer J., Lehnert G. Int. Arch. Occup. Environ. Health 1997, 69:399.
5. Becker K., Kaus S., Krause C., Lepom P., Schulz C., Seiwert M., Seifert B. Int. J. Hyg. Environ. Health 2002, 205:297.
6. Wittsiepe J., Fürst P., Schrey P., Lemm F., Kraft M., Eberwein G., Winneke G., Wilhelm M. Chemosphere 2007, 67:S286.
7. Schettgen T., Gube M., Alt A., Fromme H., Kraus T. Int. J. Hyg. Environ. Health 2011, 214:319.
8. Conka K., Drobna B., Kocan A., Petrik J. J. Chromatogr. A 2005, 1084:33.
9. Lopez R., Goni F., Etxandia A., Millan E. J. Chromatogr. B 2007, 846:298.
10. Ramos J.J., Gomara B., Fernandez M.A., Gonzalez M.J. J. Chromatogr. A 2007, 1152:124.
11. Poli D., Caglieri A., Goldoni M., Castoldi A.F., Coccini T., Roda E., Vitalone A., Ceccatelli S., Mutti A. J. Chromatogr. B 2009, 877:773.
12. Tran B.N., Zhang L., Jansing R., Aldous K. J. Chromatogr. B 2009, 877:1109.
13. Zhang Z.L., Rhind S.M. Talanta 2011, 84:487.
14. Goni F., Lopez R., Etxeandia A., Millan E., Vives A., Amiano P. Chemosphere 2009, 76:1533.
15. Lu D., Wang D., Ip H.S., Barley F., Ramage R., She J. J. Chromatogr. B 2012, 891-892:36.
16. Focant J.F., Pirard C., De Pauw E. Talanta 2004, 63:1101.
17. Sjodin A., Jones R.S., Lapeza C.R., Focant J.F., McGahee E.E., Patterson D.G. Anal. Chem. 2004, 76:1921.
18. Focant J.F., Eppe G., Massart A.C., Scholl G., Pirard C., De Pauw E. J. Chromatogr. A 2006, 1130:97.
19. Rossetti G., Mosca S., Guerriero E., Rotatori M. J. Environ. Monit. 2012, 14:1082.
20. Pena-Abaurrea M., Ramos J.J., Gonzalez M.J., Ramos L. J. Chromatogr. A 2013, 1273:18.
21. Abdel-Rehim M. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2004, 801:317.
22. Abdel-Rehim M. J. Chromatogr. A 2010, 1217:2569.
23. Abdel-Rehim M. Anal. Chim. Acta 2011, 701:119.
24. Ramautar R., Somsen G.W., de Jong G.J. Electrophoresis 2010, 31:44.
25. Buszewski B., Szultka M. Crit. Rev. Anal. Chem. 2012, 42:198.
26. Annesley T.M. Clin. Chem. 2003, 49:1041.
27. Antignac J.P., de Wasch K., Monteau F., De Brabander H., Andre F., Le Bizec B. Anal. Chim. Acta 2005, 529:129.