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Volumn 11, Issue 5, 2013, Pages 560-565

The identification and pharmacokinetic studies of metabolites of salvianolic acid B after intravenous administration in rats

Author keywords

Identification; Metabolites; Pharmacokinetics; Salvianolic acid B

Indexed keywords

ACETONITRILE; CHLORAMPHENICOL; DRUG METABOLITE; LITHOSPERMIC ACID; METHANOL; SALVIANOLIC ACID B;

EID: 84890808756     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(13)60101-6     Document Type: Article
Times cited : (19)

References (11)
  • 1
    • 0033834524 scopus 로고    scopus 로고
    • Salvianolic acid B protects the memory functions against transient cerebral ischemia in mice [J]
    • Du GH, Qiu Y, Zhang JT Salvianolic acid B protects the memory functions against transient cerebral ischemia in mice [J]. J Asian Nat Prod Res 2000, 2(2):145-152.
    • (2000) J Asian Nat Prod Res , vol.2 , Issue.2 , pp. 145-152
    • Du, G.H.1    Qiu, Y.2    Zhang, J.T.3
  • 2
    • 79955776388 scopus 로고    scopus 로고
    • Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection [J]
    • Ho JHC, Hong CY Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection [J]. J Biomed Sci 2011, 18(1):30-34.
    • (2011) J Biomed Sci , vol.18 , Issue.1 , pp. 30-34
    • Ho, J.H.C.1    Hong, C.Y.2
  • 3
    • 33646567844 scopus 로고    scopus 로고
    • Salvianolic acid B attenuates cyclooxygenase-2 expression in vitro in LPS-treated human aortic smooth muscle cells and in vivo in the apolipoprotein-E-deficient mouse aorta [J]
    • Chen YL, Hu CS, Lin FY, et al. Salvianolic acid B attenuates cyclooxygenase-2 expression in vitro in LPS-treated human aortic smooth muscle cells and in vivo in the apolipoprotein-E-deficient mouse aorta [J]. J Cell Biochem 2006, 98(3):618-631.
    • (2006) J Cell Biochem , vol.98 , Issue.3 , pp. 618-631
    • Chen, Y.L.1    Hu, C.S.2    Lin, F.Y.3
  • 4
    • 38349123913 scopus 로고    scopus 로고
    • Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion [J]
    • Han JY, Fan JY, Horie Y, et al. Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion [J]. Pharmacol Ther 2008, 117(2):280-295.
    • (2008) Pharmacol Ther , vol.117 , Issue.2 , pp. 280-295
    • Han, J.Y.1    Fan, J.Y.2    Horie, Y.3
  • 5
    • 4644325763 scopus 로고    scopus 로고
    • Inhibition of shear-induced platelet aggregation in rat by tetramethylpyrazine and salvianolic acid B [J]
    • Li M, Zhao C, Wong RN, et al. Inhibition of shear-induced platelet aggregation in rat by tetramethylpyrazine and salvianolic acid B [J]. Clin Hemorheol Microcirc 2004, 31(2):97-103.
    • (2004) Clin Hemorheol Microcirc , vol.31 , Issue.2 , pp. 97-103
    • Li, M.1    Zhao, C.2    Wong, R.N.3
  • 6
    • 33947302110 scopus 로고    scopus 로고
    • Salvianolic acid B modulates hemostasis properties of human umbilical vein endothelial cells [J]
    • Shi CS, Huang HC, Wu HL, et al. Salvianolic acid B modulates hemostasis properties of human umbilical vein endothelial cells [J]. Thromb Res 2007, 119(6):769-775.
    • (2007) Thromb Res , vol.119 , Issue.6 , pp. 769-775
    • Shi, C.S.1    Huang, H.C.2    Wu, H.L.3
  • 7
    • 1542344491 scopus 로고    scopus 로고
    • Extremely low bioavailability of magnesium lithospermate B, an active component from Salvia miltiorrhiza, in rat [J]
    • Zhang Y, Akao T, Nakamura N, et al. Extremely low bioavailability of magnesium lithospermate B, an active component from Salvia miltiorrhiza, in rat [J]. Planta Med 2004, 70(2):138-142.
    • (2004) Planta Med , vol.70 , Issue.2 , pp. 138-142
    • Zhang, Y.1    Akao, T.2    Nakamura, N.3
  • 8
    • 33750470777 scopus 로고    scopus 로고
    • Bioavailability of salvianolic acid B in conscious and freely moving rats [J]
    • Wu YT, Chen YF, Hsieh YJ, et al. Bioavailability of salvianolic acid B in conscious and freely moving rats [J]. Int J Pharm 2006, 326(1):25-31.
    • (2006) Int J Pharm , vol.326 , Issue.1 , pp. 25-31
    • Wu, Y.T.1    Chen, Y.F.2    Hsieh, Y.J.3
  • 9
    • 33846422712 scopus 로고    scopus 로고
    • Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats [J]
    • Li X, Yu C, Lu Y, et al. Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats [J]. Drug Metab Dispos 2007, 35(2):234-239.
    • (2007) Drug Metab Dispos , vol.35 , Issue.2 , pp. 234-239
    • Li, X.1    Yu, C.2    Lu, Y.3
  • 10
    • 3042634920 scopus 로고    scopus 로고
    • Magnesium lithospermate B is excreted rapidly into rat bile mostly as methylated metabolites, which are potent antioxidants [J]
    • Zhang Y, Akao T, Nakamura N, et al. Magnesium lithospermate B is excreted rapidly into rat bile mostly as methylated metabolites, which are potent antioxidants [J]. Drug Metab Dispos 2004, 32(7):752-757.
    • (2004) Drug Metab Dispos , vol.32 , Issue.7 , pp. 752-757
    • Zhang, Y.1    Akao, T.2    Nakamura, N.3
  • 11
    • 34848814434 scopus 로고    scopus 로고
    • Structural characterization of metabolites of salvianolic acid B from Salvia miltiorrhiza in normal and antibiotic-treated rats by liquid chromatography-mass spectrometry [J]
    • Xu M, Guo H, Han J, et al. Structural characterization of metabolites of salvianolic acid B from Salvia miltiorrhiza in normal and antibiotic-treated rats by liquid chromatography-mass spectrometry [J]. J Chromatogr B Analyt Technol Biomed Life Sci 2007, 858(1-2):184-198.
    • (2007) J Chromatogr B Analyt Technol Biomed Life Sci , vol.858 , Issue.1-2 , pp. 184-198
    • Xu, M.1    Guo, H.2    Han, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.