Continuous versus intermittent infusion of cefepime in neurosurgical patients with post-operative intracranial infections

International Journal of Antimicrobial Agents

Volumn 43, Issue 1, 2014, Pages 68-72

  Huang, Huawei ^a   Huang, Shengyue ^b   Zhu, Pengli ^b   Xi, Xiuming ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Cefepime; Continuous infusion; Intermittent infusion; Intracranial infection; Minimum inhibitory concentration

Indexed keywords

CEFEPIME;

ADULT; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BRAIN INFECTION; COMPARATIVE STUDY; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG RESPONSE; FEMALE; HUMAN; INFUSION; INTERMITTENT INFUSION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MINIMUM INHIBITORY CONCENTRATION; NEUROSURGERY; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TREATMENT DURATION;

CEFEPIME; CONTINUOUS INFUSION; INTERMITTENT INFUSION; INTRACRANIAL INFECTION; MINIMUM INHIBITORY CONCENTRATION;

ADULT; AGED; ANTI-BACTERIAL AGENTS; CEPHALOSPORINS; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MENINGITIS, BACTERIAL; MIDDLE AGED; NEUROSURGICAL PROCEDURES; PLASMA; POSTOPERATIVE COMPLICATIONS; RETROSPECTIVE STUDIES;

EID: 84890799085     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2013.08.019     Document Type: Article

References (27)

1. J.F. Roos, J. Bulitta, J. Lipman, and C.M. Kirkpatrick Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units J Antimicrob Chemother 58 2006 987 993
2. S. Jaruratanasirikul, S. Sriwiriyajan, and N. Ingviya Continuous infusion versus intermittent administration of cefepime in patients with Gram-negative bacilli bacteraemia J Pharm Pharmacol 54 2002 1693 1696
3. M.R. Rafati, M.R. Rouini, M. Mojtahedzadeh, A. Najafi, H. Tavakoli, and K. Gholami Clinical efficacy of continuous infusion of piperacillin compared with intermittent dosing in septic critically ill patients Int J Antimicrob Agents 28 2006 122 127
4. W.A. Craig Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men Clin Infect Dis 26 1998 1 10 11-12
5. J.A. Roberts, J. Paratz, E. Paratz, W.A. Krueger, and J. Lipman Continuous infusion of β-lactam antibiotics in severe infections: a review of its role Int J Antimicrob Agents 30 2007 11 18
6. S.K. Kasiakou, K.R. Lawrence, N. Choulis, and M.E. Falagas Continuous versus intermittent intravenous administration of antibacterials with time-dependent action: a systematic review of pharmacokinetic and pharmacodynamic parameters Drugs 65 2005 2499 2511
7. J.W. Mouton, and J.G. den Hollander Killing of Pseudomonas aeruginosa during continuous and intermittent infusion of ceftazidime in an in vitro pharmacokinetic model Antimicrob Agents Chemother 38 1994 931 936
8. C. Li, X. Du, J.L. Kuti, and D.P. Nicolau Clinical pharmacodynamics of meropenem in patients with lower respiratory tract infections Antimicrob Agents Chemother 51 2007 1725 1730
9. M.A. Robaux, L. Dube, J. Caillon, D. Bugnon, M.F. Kergueris, and D. Navas In vivo efficacy of continuous infusion versus intermittent dosing of ceftazidime alone or in combination with amikacin relative to human kinetic profiles in a Pseudomonas aeruginosa rabbit endocarditis model J Antimicrob Chemother 47 2001 617 622
10. L. Piccoli, M. Larosa, and F. Marchetti Time-kill curves as a tool for targeting ceftazidime serum concentration during continuous infusion J Antimicrob Chemother 52 2003 1047 1048
11. J.A. Roberts, S. Webb, D. Paterson, K.M. Ho, and J. Lipman A systematic review on clinical benefits of continuous administration of β-lactam antibiotics Crit Care Med 37 2009 2071 2078
12. X. Sáez-Llorens, E. Castaño, R. García, C. Báez, M. Pérez, and F. Tejeira Prospective randomized comparison of cefepime and cefotaxime for treatment of bacterial meningitis in infants and children Antimicrob Agents Chemother 39 1995 937 940
13. D.H. Rhoney, V.H. Tam, D.J. Parker, P.S. McKinnon, and W.M. Coplin Disposition of cefepime in the central nervous system of patients with external ventricular drains Pharmacotherapy 23 2003 310 314
14. J.L. Blumer, M.D. Reed, and C. Knupp Review of the pharmacokinetics of cefepime in children Pediatr Infect Dis J 20 2001 337 342
15. L. Lorente, A. Jiménez, M.M. Martín, J.L. Iribarren, J.J. Jiménez, and M.L. Mora Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion Int J Antimicrob Agents 33 2009 464 468
16. B. Georges, J.M. Conil, P. Cougot, J.F. Decun, M. Archambaud, and T. Seguin Cefepime in critically ill patients: continuous infusion vs. an intermittent dosing regimen Int J Clin Pharmacol Ther 43 2005 360 369
17. J.J. McNabb, C.H. Nightingale, R. Quintiliani, and D.P. Nicolau Cost-effectiveness of ceftazidime by continuous infusion versus intermittent infusion for nosocomial pneumonia Pharmacotherapy 21 2001 549 555
18. N.R. Florea, S. Kotapati, J.L. Kuti, E.C. Geissler, C.H. Nightingale, and D.P. Nicolau Cost analysis of continuous versus intermittent infusion of piperacillin-tazobactam: a time-motion study Am J Health Syst Pharm 60 2003 2321 2327
19. D.M. Cappelletty, S.L. Kang, S.M. Palmer, and M.J. Rybak Pharmacodynamics of ceftazidime administered as continuous infusion or intermittent bolus alone and in combination with single daily-dose amikacin against Pseudomonas aeruginosa in an in vitro infection model Antimicrob Agents Chemother 39 1995 1797 1801
20. D.S. Burgess, R.W. Hastings, and T.C. Hardin Pharmacokinetics and pharmacodynamics of cefepime administered by intermittent and continuous infusion Clin Ther 22 2000 66 75
21. W.A. Craig Interrelationship between pharmacokinetics and pharmacodynamics in determining dosage regimens for broad-spectrum cephalosporins Diagn Microbiol Infect Dis 22 1995 89 96
22. D.P. Nicolau, J. McNabb, M.K. Lacy, R. Quintiliani, and C.H. Nightingale Continuous versus intermittent administration of ceftazidime in intensive care unit patients with nosocomial pneumonia Int J Antimicrob Agents 17 2001 497 504
23. J.M. Dulhunty, J.A. Roberts, J.S. Davis, S.A. Webb, R. Bellomo, and C. Gomersall Continuous infusion of β-lactam antibiotics in severe sepsis: a multicenter double-blind, randomized controlled trial Clin Infect Dis 56 2013 236 244
24. J.F. Wang, Q. Wang, L.H. Zhao, G.Z. Shi, and J.X. Zhou Blood-brain barrier penetration of cefepime after neurosurgery Chin Med J (Engl) 120 2007 1176 1178
25. R.N. Jones, H.S. Sader, and M.L. Beach Contemporary in vitro spectrum of activity summary for antimicrobial agents tested against 18569 strains non-fermentative Gram-negative bacilli isolated in the SENTRY Antimicrobial Surveillance Program (1997-2001) Int J Antimicrob Agents 22 2003 551 556
26. A. McNally, A. Pithie, and D. Jardine Cefepime: a rare cause of encephalopathy Intern Med J 42 2012 732 733
27. S.D. Alvarez, C. Aragon Mdel, A. Moreno, F. Palomares-Alonso, H.J. Cook, and G. Cardenas Clinical and electroencephalographic assessment of cefepime during treatment of nosocomial infections in neurological patients Cent Nerv Syst Agents Med Chem 11 2011 223 227