12-Amino-andrographolide analogues: Synthesis and cytotoxic activity

Archives of Pharmacal Research

Volumn 36, Issue 12, 2013, Pages 1454-1464

  Kasemsuk, Sakkasem ^a   Sirion, Uthaiwan ^a   Suksen, Kanoknetr ^b   Piyachaturawat, Pawinee ^b   Suksamrarn, Apichart ^c   Saeeng, Rungnapha ^a  

^a BURAPHA UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c RAMKHAMHAENG UNIVERSITY   (Thailand)

Author keywords

12 Amino andrographolide; Andrographis paniculata; Cytotoxic activity; Tandem aza conjugate addition elimination

Indexed keywords

12 ((2 FLUORO)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((3 FLUORO)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((3,4 DIMETHOXY)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((3,5 DICHLORO 4 HYDROXY)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((4 BROMO)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((4 CARBOXYL)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((4 FLUORO)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((4 HYDROXY)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((4 METHANOL)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 ((4 METHOXY)PHENYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 (NAPHTHYL)AMINO 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 (PHENYL)AMINO 19 TBS 3 AC 14 DEOXY ANDROGRAPHOLIDE; 12 MORPHOLINYL 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; 12 PYRROLIDINYL 19 TBS 3 AC 14 DEOXYANDROGRAPHOLIDE; ANDROGRAPHOLIDE; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CATALYST; CYTOTOXICITY; DRUG SYNTHESIS; ELIMINATION REACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; ROOM TEMPERATURE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANDROGRAPHIS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYTOTOXINS; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MCF-7 CELLS; MICE; PLANT COMPONENTS, AERIAL; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84890798430     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0152-0     Document Type: Article

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