Detection of molecular alterations in methamphetamine-activated Fos-expressing neurons from a single rat dorsal striatum using fluorescence-activated cell sorting (FACS)

Journal of Neurochemistry

Volumn 128, Issue 1, 2014, Pages 173-185

  Liu, Qing Rong ^a   Rubio, Francisco J ^a   Bossert, Jennifer M ^a   Marchant, Nathan J ^a   Fanous, Sanya ^a   Hou, Xingyu ^a   Shaham, Yavin ^a   Hope, Bruce T ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

flow cytometry; gene expression; immediate early genes

Indexed keywords

MESSENGER RNA; METHAMPHETAMINE; NEURON SPECIFIC NUCLEAR PROTEIN; PROTEIN FOS; PROTEIN HOMER 2; TRANSCRIPTION FACTOR FOSB;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARC GENE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; CORPUS STRIATUM; FLUORESCENCE ACTIVATED CELL SORTING; FOSB GENE; GENE EXPRESSION; GENE INDUCTION; HOMER 2 GENE; IMMEDIATE EARLY GENE; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL STIMULATION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

FLOW CYTOMETRY; GENE EXPRESSION; IMMEDIATE EARLY GENES;

AMINO ACID SEQUENCE; ANIMALS; CORPUS STRIATUM; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; MALE; METHAMPHETAMINE; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84890796562     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12381     Document Type: Article

References (42)

1. Badiani A., Belin D., Epstein D., Calu D., and, Shaham Y., (2011) Opiate versus psychostimulant addiction: the differences do matter. Nat. Rev. Neurosci. 12, 685-700.
2. Bossert J. M., Stern A. L., Theberge F. R., Cifani C., Koya E., Hope B. T., and, Shaham Y., (2011) Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin. Nat. Neurosci. 14, 420-422.
3. Bossert J. M., Stern A. L., Theberge F. R., Marchant N. J., Wang H. L., Morales M., and, Shaham Y., (2012) Role of projections from ventral medial prefrontal cortex to nucleus accumbens shell in context-induced reinstatement of heroin seeking. J. Neurosci. 32, 4982-4991.
4. Bossert J. M., Marchant N. J., Calu D. J., and, Shaham Y,. (2013) The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology. [Epub ahead of print].
5. Carelli R. M., and, Wightman R. M., (2004) Functional microcircuitry in the accumbens underlying drug addiction: insights from real-time signaling during behavior. Curr. Opin. Neurobiol. 14, 763-768. (Pubitemid 39576210)
6. Chang J. Y., Janak P. H., and, Woodward D. J., (1998) Comparison of mesocorticolimbic neuronal responses during cocaine and heroin self-administration in freely moving rats. J. Neurosci. 18, 3098-3115. (Pubitemid 28163239)
7. Chen J., Nye H. E., Kelz M. B., Hiroi N., Nakabeppu Y., Hope B. T., and, Nestler E. J., (1995) Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments. Mol. Pharmacol. 48, 880-889. (Pubitemid 3015243)
8. Chen J., Kelz M. B., Hope B. T., Nakabeppu Y., and, Nestler E. J., (1997) Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments. J. Neurosci. 17, 4933-4941. (Pubitemid 27263807)
9. Cifani C., Koya E., Navarre B. M., et al,. (2012) Medial prefrontal cortex neuronal activation and synaptic alterations after stress-induced reinstatement of palatable food seeking: a study using c-fos-GFP transgenic female rats. J. Neurosci. 32, 8480-8490.
10. Cruz F. C., Koya E., Guez-Barber D. H., Bossert J. M., Lupica C. R., Shaham Y., and, Hope B. T., (2013) New technologies for examining the role of neuronal ensembles in drug addiction and fear. Nat. Rev. Neurosci. (in press).
11. Curran T., and, Morgan J. I., (1995) Fos: an immediate-early transcription factor in neurons. J. Neurobiol. 26, 403-412.
12. Fanous S., Goldart E. M., Theberge F. R., Bossert J. M., Shaham Y., and, Hope B. T., (2012) Role of orbitofrontal cortex neuronal ensembles in the expression of incubation of heroin craving. J. Neurosci. 32, 11600-11609.
13. Fanous S., Guez-Barber D. H., Goldart E. M., Schrama R., Theberge F. R., Shaham Y., and, Hope B. T., (2013) Unique gene alterations are induced in FACS-purified Fos-positive neurons activated during cue-induced relapse to heroin seeking. J. Neurochem. 124, 100-108.
14. Grueter B. A., Robison A. J., Neve R. L., Nestler E. J., and, Malenka R. C., (2013) FosB differentially modulates nucleus accumbens direct and indirect pathway function. Proc. Natl Acad. Sci. USA 110, 1923-1928.
15. Guez-Barber D., Fanous S., Golden S. A., et al,. (2011) FACS identifies unique cocaine-induced gene regulation in selectively activated adult striatal neurons. J. Neurosci. 31, 4251-4259.
16. Guez-Barber D., Fanous S., Harvey B. K., Zhang Y., Lehrmann E., Becker K. G., Picciotto M. R., and, Hope B. T., (2012) FACS purification of immunolabeled cell types from adult rat brain. J. Neurosci. Methods 203, 10-18.
17. Guzowski J. F., McNaughton B. L., Barnes C. A., and, Worley P. F., (1999) Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles. Nat. Neurosci. 2, 1120-1124. (Pubitemid 30126371)
18. Hamlin A. S., Newby J., and, McNally G. P., (2007) The neural correlates and role of D1 dopamine receptors in renewal of extinguished alcohol-seeking. Neuroscience 146, 525-536. (Pubitemid 46617057)
19. Hope B. T., Kelz M. B., Duman R. S., and, Nestler E. J., (1994a) Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics. J. Neurosci. 14, 4318-4328. (Pubitemid 24200554)
20. Hope B. T., Nye H. E., Kelz M. B., Self D. W., Iadarola M. J., Nakabeppu Y., Duman R. S., and, Nestler E. J., (1994b) Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron 13, 1235-1244. (Pubitemid 24372141)
21. Hope B. T., Simmons D. E., Mitchell T. B., Kreuter J. D., and, Mattson B. J., (2006) Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage. Eur. J. Neurosci. 24, 867-875. (Pubitemid 44232530)
22. Kelz M. B., Chen J., Carlezon W. A., Jr, et al,. (1999) Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature 401, 272-276.
23. Kiyatkin E. A., and, Rebec G. V., (1997) Activity of presumed dopamine neurons in the ventral tegmental area during heroin self-administration. NeuroReport 8, 2581-2585. (Pubitemid 27308465)
24. Koya E., Golden S. A., Harvey B. K., et al,. (2009) Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization. Nat. Neurosci. 12, 1069-1073.
25. Lobo M. K., (2009) Molecular profiling of striatonigral and striatopallidal medium spiny neurons past, present, and future. Int. Rev. Neurobiol. 89, 1-35.
26. Lobo M. K., Karsten S. L., Gray M., Geschwind D. H., and, Yang X. W., (2006) FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains. Nat. Neurosci. 9, 443-452. (Pubitemid 43290975)
27. Mattson B. J., Koya E., Simmons D. E., Mitchell T. B., Berkow A., Crombag H. S., and, Hope B. T., (2008) Context-specific sensitization of cocaine-induced locomotor activity and associated neuronal ensembles in rat nucleus accumbens. Eur. J. Neurosci. 27, 202-212.
28. McClung C. A., Ulery P. G., Perrotti L. I., Zachariou V., Berton O., and, Nestler E. J., (2004) DeltaFosB: a molecular switch for long-term adaptation in the brain. Brain Res. Mol. Brain Res. 132, 146-154. (Pubitemid 39586757)
29. Morgan J. I., and, Curran T., (1991) Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu. Rev. Neurosci. 14, 421-451.
30. Mullen R. J., Buck C. R., and, Smith A. M., (1992) NeuN, a neuronal specific nuclear protein in vertebrates. Development 116, 201-211.
31. Nair S. G., Navarre B. M., Cifani C., Pickens C. L., Bossert J. M., and, Shaham Y., (2011) Role of dorsal medial prefrontal cortex dopamine D1-family receptors in relapse to high-fat food seeking induced by the anxiogenic drug yohimbine. Neuropsychopharmacology 36, 497-510.
32. Nakabeppu Y., and, Nathans D., (1991) A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity. Cell 64, 751-759. (Pubitemid 121001162)
33. Neisewander J. L., Baker D. A., Fuchs R. A., Tran-Nguyen L. T., Palmer A., and, Marshall J. F., (2000) Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environment. J. Neurosci. 20, 798-805. (Pubitemid 30225582)
34. Nestler E. J., (2001) Molecular basis of long-term plasticity underlying addiction. Nat. Rev. Neurosci. 2, 119-128. (Pubitemid 33673366)
35. Nestler E. J., (2002) From neurobiology to treatment: progress against addiction. Nat. Neurosci. 5 (Suppl), 1076-1079. (Pubitemid 35247203)
36. Perrotti L. I., Weaver R. R., Robison B., et al,. (2008) Distinct patterns of DeltaFosB induction in brain by drugs of abuse. Synapse 62, 358-369. (Pubitemid 351451804)
37. Shaham Y., and, Hope B. T., (2005) The role of neuroadaptations in relapse to drug seeking. Nat. Neurosci. 8, 1437-1439. (Pubitemid 41573651)
38. Theberge F. R., Pickens C. L., Goldart E., Fanous S., Hope B. T., Liu Q. R., and, Shaham Y., (2012) Association of time-dependent changes in mu opioid receptor mRNA, but not BDNF, TrkB, or MeCP2 mRNA and protein expression in the rat nucleus accumbens with incubation of heroin craving. Psychopharmacology 224, 559-571.
39. White F. J., and, Kalivas P. W., (1998) Neuroadaptations involved in amphetamine and cocaine addiction. Drug Alcohol Depend. 51, 141-153. (Pubitemid 28353762)
40. Wolf M. E., Sun X., Mangiavacchi S., and, Chao S. Z., (2004) Psychomotor stimulants and neuronal plasticity. Neuropharmacology 47 (Suppl 1), 61-79. (Pubitemid 39298253)
41. Worley P. F., Zeng W., Huang G., Kim J. Y., Shin D. M., Kim M. S., Yuan J. P., Kiselyov K., and, Muallem S., (2007) Homer proteins in Ca2 + signaling by excitable and non-excitable cells. Cell Calcium 42, 363-371. (Pubitemid 47264010)
42. Zachariou V., Bolanos C. A., Selley D. E., et al,. (2006) An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nat. Neurosci. 9, 205-211. (Pubitemid 43164543)