Glomerular disease: The role of parietal epithelial cells in hyperplastic lesions

Nature Reviews Nephrology

Volumn 10, Issue 1, 2014, Pages 5-6

  Moeller, Marcus J ^a   Kuppe, Christoph ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; GLOMERULUS EPITHELIUM; HUMAN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEIN ANALYSIS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION;

ANIMALS; CELL PROLIFERATION; EPITHELIAL CELLS; FEMALE; GLOMERULAR MESANGIUM; GLOMERULONEPHRITIS; HUMANS; INFLAMMATION MEDIATORS; MALE; STEM CELLS;

EID: 84890796211     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2013.252     Document Type: Article

References (10)

1. Rizzo, P. et al. Nature and mediators of parietal epithelial cell activation in glomerulonephritides of human and rat. Am. J. Pathol. http://dx.doi.org/10.1016/j.ajpath.2013.08.008.
2. Berger, K. et al. The regenerative potential of parietal epithelial cells in adult mice. J. Am. Soc. Nephrol. (in press).
3. Ding, M. et al. Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nat. Med. 12, 1081-1087 (2006).
4. Fatima, H. et al. Parietal epithelial cell activation marker in early recurrence of FSGS in the transplant. Clin. J. Am. Soc. Nephrol. 7, 1852-1858 (2012).
5. Le Hir, M. & Besse-Eschmann, V. A novel mechanism of nephron loss in a murine model of crescentic glomerulonephritis. Kidney Int. 63, 591-599 (2003).
6. Smeets, B. et al. Tracing the origin of glomerular extracapillary lesions from parietal epithelial cells. J. Am. Soc. Nephrol. 20, 2604-2615 (2009).
7. Smeets, B. & Moeller, M. J. Parietal epithelial cells and podocytes in glomerular diseases. Semin. Nephrol. 32, 357-367 (2012).
8. Smeets, B. et al. Angiotensin converting enzyme inhibition prevents development of collapsing focal segmental glomerulosclerosis in Thy-1.1 transgenic mice. Nephrol. Dial. Transplant. 21, 3087-3097 (2006).
9. Ronconi, E. et al. Regeneration of glomerular podocytes by human renal progenitors. J. Am. Soc. Nephrol. 20, 322-332 (2009).
10. Appel, D. et al. Recruitment of podocytes from glomerular parietal epithelial cells. J. Am. Soc. Nephrol. 20, 333-343 (2009).