Changes in the gene expression pattern induced by 2-methoxyestradiol in the mouse uterus

Endocrine

Volumn 44, Issue 3, 2013, Pages 773-783

  Rincón Rodríguez, Ramiro J ^a,b,d   Oróstica, María L ^a,b   Díaz, Patricia ^a,b   Reuquén, Patricia ^a,c   Cárdenas, Hugo ^a,b   Orihuela, Pedro A ^a,b  

^a UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^b CENTER FOR THE DEVELOPMENT OF NANOSCIENCE AND NANOTECHNOLOGY CEDENNA   (Chile)

^c UNIVERSIDAD ANDRÉS BELLO   (Chile)

^d UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

2 Methoxyestradiol; F spondin; Microarray; Mouse; Uterus

Indexed keywords

2 METHOXYESTRADIOL; CELL PROTEIN; ESTRADIOL; F SPONDIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY FOLLICLE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; SCD2 GENE; SEQUENCE ANALYSIS; SNX6 GENE; SPON1 GENE; UPREGULATION; UTERUS WEIGHT;

ANIMALS; ESTRADIOL; FEMALE; GENE EXPRESSION; MICE; PEPTIDES; SORTING NEXINS; STEAROYL-COA DESATURASE; UTERUS;

EID: 84890793220     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-013-9921-2     Document Type: Article

References (37)

1. R. Knuppen, P. Ball, G. Emons, Importance of A-ring substitution of estrogens for the physiology and pharmacology of reproduction. J. Steroid Biochem. 24, 193-198 (1986)
2. C.P. Martucci, J. Fishman, P450 enzymes of estrogen metabolism. Pharmacol. Ther. 57, 237-257 (1993)
3. B.T. Zhu, A.H. Conney, Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 19, 1-37 (1998)
4. B.T. Zhu, G. Han, I. Shim, Y. Wen, X. Jiang, Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor and subtypes: insights into the structural determinants favoring a differential subtype binding. Endocrinology 147, 4132-4150 (2006)
5. T.M. LaVallee, X.H. Zhan, C.J. Herbstritt, E.C. Kough, S.J. Green, S.V. Pribluda, 2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors α and β. Cancer Res. 1, 3691-3697 (2002)
6. A. Parada-Bustamante, P.A. Orihuela, M. Rios, P.A. Navarrete- Gómez, C.A. Cuevas, L.A. Velasquez, M.J. Villalón, H.B. Croxatto, Catechol-o-methyltransferase and methoxyestradiols participate in the intraoviductal nongenomic pathway through which estradiol accelerates egg transport in cycling rats. Biol. Reprod. 77, 934-941 (2007)
7. N.J. Mabjeesh, D. Escuin, M.T. LaVallee, V.S. Pribluda, G.M. Swartz, M.S. Johnson, M.T. Willard, H. Zhong, J.W. Simons, P. Giannakakou, 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell 3, 363-375 (2003)
8. A. Sadarangani, S. Kato, N. Espinoza, S. Lange, C. Llados, M. Espinosa, M. Villalon, S. Lipkowitz, M. Cuello, G.I. Owen, TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract. Apoptosis 12, 73-85 (2007)
9. S. Kato, A. Sadarangani, S. Lange, M. Villalón, J. Brañes, J.J. Brosens, G.I. Owen, M. Cuello, The oestrogen metabolite 2-methoxy-oestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium. Endocr. Relat. Cancer 14, 351-368 (2007)
10. R.J. D'Amato, C.M. Lin, E. Flynn, J. Folkman, E. Hamel, 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site. Proc. Natl. Acad. Sci. USA 91, 3964-3968 (1994)
11. R. Bathi, Y. Gökmen-Polar Jr, G.W. Sledger, Ch. Fan, H. Nakshatri, D. Ketelsen, C.H. Borchers, M.J. Dial, C. Patterson, N. Klauber-DeMore, 2-Methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells. Cancer Res. 67, 702-708 (2007)
12. L. Dehennin, C. Blacker, A. Reiffsteck, R. Scholler, Estrogen 2-, 4-, 6- or 16-hydroxylation by human follicles shown by gas chromatography-mass spectrometry associated with stable isotope dilution. J. Steroid Biochem. 20, 465-471 (1984)
13. P. Silberzahn, G.H. Almahbobi, L. Dehennin, A. Merouane, Estrogen metabolites in equine ovarian follicles: gas chromatographic-mass spectrophotometric determinations in relation to follicular ultrastructure and progestin content. J. Steroid Biochem. 22, 501-505 (1985)
14. C.M. Barnes, T.F. McElrath, J. Folkman, A.R. Hansen, Correlation of 2-methoxyestradiol levels in cord blood and complications of prematurity. Pediatr. Res. 67, 545-550 (2010)
15. M.L. Lattanzi, C.B. Santos, M.D. Mudry, J.L. Baranao, Exposure of bovine oocytes to the endogenous metabolite 2-methoxyestradiol during in vitro maturation inhibits early embryonic development. Biol. Reprod. 69, 1793-1800 (2003)
16. J.D. Sibonga, S. Lotinun, G.L. Evans, V.S. Pribluda, S.J. Green, R.T. Turner, Dose-response effects of 2-methoxyestradiol on estrogen target tissues in the ovariectomized rat. Endocrinology 144, 785-792 (2003)
17. D. Chauhan, G. Li, D. Auclair, T. Hideshima, P. Richardson, K. Podar, N. Mitsiades, C. Mitsiades, Ch. Li, R.S. Kim, N. Munshi, L.B. Chen, W. Wong, K.C. Anderson, Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays. Blood 1001, 3606-3614 (2003)
18. M. Miyazaki, F.E. Gomez, J.M. Ntambi, Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoAΔ6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse. J. Lipid Res. 43, 2146-2154 (2002)
19. W.T. Parks, D.B. Frank, C. Huff, C.F. Haft, J. Martin, X. Meng, M.P. Caestecker, J.G. McNally, A. Reddi, S.I. Taylor, A.R. Roberts, T. Wang, R.J. Lechleider, Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-β family of receptor serine-threonine kinases. J. Biol. Chem. 276, 19332-19339 (2001)
20. M.E. Cavet, J. Pang, G. Yin, B.C. Berk, An epidermal growth factor (EGF)-dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor. FASEB J. 22, 3607-3616 (2008)
21. H.-S. Hoe, D. Wessner, U. Beffert, A.G. Becker, Y. Matsuoka, G.W. Rebeck, F-spondin interaction with the apolipoprotein E receptor ApoEr2 affects processing of amyloid precursor protein. Mol. Cell. Biol. 25, 9259-9268 (2005)
22. K. Miyamoto, Y. Morishita, M. Yamazaki, N. Minamino, K. Kangawa, H. Matsuo, T. Mizutani, K. Yamada, T. Minegishi, Isolation and characterization of vascular smooth muscle cell growth promoting factor from bovine ovarian follicular fluid and its cDNA cloning from bovine and human ovary. Arch. Biochem. Biophys. 390, 93-100 (2001)
23. C.D. Turner, in General Endocrinology, 3rd edn. (WB Saunders Company, Philadelphia, 1961) pp. 365-409
24. P.A. Orihuela, H.B. Croxatto, Acceleration of oviductal transport of oocytes induced by estradiol in cycling rats is mediated by nongenomic stimulation of protein phosphorylation in the oviduct. Biol. Reprod. 65, 1238-1245 (2001)
25. R. Mayol, S.A. Thayer, Synthesis of estrogen-specific proteins in the uterus of immature rat. Biochemistry 9, 2484-2489 (1970)
26. R. Grümer, K. Chwalisz, J. Mulholland, O. Traub, E. Winterhager, Regulation of connexin26 and connexin43 expression in rat endometrium by ovarian steroid hormones. Biol. Reprod. 51, 1109-1116 (1994)
27. G.K. Smyth, Limma: linear models for microarray data, in Bioinformatics and Computational Biology Solutions Using R and Bioconductor, ed. by V. Carey, S. Dudoit, R. Irizarry, W. Huber (Springer, New York, 2005), pp. 397-420
28. J.M. Herbert, D. Steckel, S. Sanderson, V.L. Heath, R. Bicknell, A novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes. BMG Genomics 9, 153 (2008)
29. M. Muscillo, G. La Rosa, C. Marianelli, S. Zaniratti, M.R. Capobianchi, L. Cantiani, A. Carducci, A new RT-PCR method for the identification of reoviruses in seawater samples. Water Res. 35, 548-556 (2001)
30. W.G. Ma, J. Tan, H. Matsumoto, B. Robert, D.R. Abrahamson, S.K. Das, S.K. Dey, Adult tissue angiogenesis: evidence for negative regulation by estrogen in the uterus. Mol. Endocrinol. 15, 1983-1992 (2001)
31. W.G. Ma, H. Song, S.K. Das, B.C. Paria, S.K. Dey, Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation. Proc. Natl. Acad. Sci. USA 90, 10159-10162 (2003)
32. K. Ohnuma, H. Kaneko, J. Noguchi, K. Kikuchi, M. Ozawa, Y. Hasegawa, Isolation and identification of F-spondin in the boar testis and its production during testis growth. J. Reprod. Dev. 53, 151-158 (2007)
33. B.A. Stander, S. Marais, C.J. Vorster, A.M. Joubert, In vitro effects of 2-methoxyestradiol on morphology, cell cycle progression, cell death and gene expression changes in the tumorigenic MCF-7 breast epithelial cell line. J. Steroid Biochem. Mol. Biol. 119, 149-160 (2010)
34. A. Maran, M. Zhang, A.M. Kennedy, J.D. Sibonga, D.J. Rickard, T.C. Spelsberg, R.T. Turner, 2-Methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells. Bone 30, 393-398 (2002)
35. R.T. Turner, G.L. Evans, J.M. Cavolina, B. Halloran, E. Morey-Holton, Programmed administration of parathyroid hormone increases bone formation and reduces bone loss in hindlimb-unloaded ovariectomized rats. Endocrinology 139, 4086-4091 (1998)
36. C. Moreau, P. Froment, L. Tosca, V. Moreau, J. DuPont, Expression and regulation of the SCD2 desaturase in the rat ovary. Biol. Reprod. 74, 75-87 (2006)
37. A.T. Fazleabas, Physiology and pathology of implantation in the human and nonhuman primate. Semin. Reprod. Med. 25, 405-409 (2007)