-
1
-
-
10344222124
-
The role of the unfolded protein response in tumour development: Friend or foe?
-
DOI 10.1038/nrc1505
-
Ma Y, Hendershot LM. The role of the unfolded protein response in tumour development: friend or foe? Nat Rev Cancer 2004;4:966-77. (Pubitemid 39626220)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.12
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
2
-
-
84874112079
-
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies
-
Luo B, Lee AS. The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies. Oncogene 2013;32:805-18.
-
(2013)
Oncogene
, vol.32
, pp. 805-818
-
-
Luo, B.1
Lee, A.S.2
-
3
-
-
33646171070
-
Stress induction of GRP78/BiP and its role in cancer
-
Li J, Lee AS. Stress induction of GRP78/BiP and its role in cancer. Curr Mol Med 2006;6:45-54.
-
(2006)
Curr Mol Med
, vol.6
, pp. 45-54
-
-
Li, J.1
Lee, A.S.2
-
4
-
-
34248571826
-
GRP78 induction in cancer: Therapeutic and prognostic implications
-
DOI 10.1158/0008-5472.CAN-07-0325
-
Lee AS. GRP78 induction in cancer: therapeutic and prognostic implications. Cancer Res 2007;67:3496-9. (Pubitemid 46762126)
-
(2007)
Cancer Research
, vol.67
, Issue.8
, pp. 3496-3499
-
-
Lee, A.S.1
-
5
-
-
84859112544
-
Glucose regulated protein 78: A critical link between tumor microenvironment and cancer hallmarks
-
Li Z, Li Z. Glucose regulated protein 78: a critical link between tumor microenvironment and cancer hallmarks. Biochim Biophys Acta 2012; 1826:13-22.
-
(2012)
Biochim Biophys Acta
, vol.1826
, pp. 13-22
-
-
Li, Z.1
Li, Z.2
-
6
-
-
35448967382
-
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
-
DOI 10.1158/0008-5472.CAN-07-0625
-
Pyrko P, Schonthal AH, Hofman FM, Chen TC, Lee AS. The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res 2007;67:9809-16. (Pubitemid 47621228)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9809-9816
-
-
Pyrko, P.1
Schontha, A.H.2
Hofman, F.M.3
Chen, T.C.4
Lee, A.S.5
-
7
-
-
52449107266
-
Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells
-
Virrey JJ, Dong D, Stiles C, Patterson JB, Pen L, Ni M, et al. Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells. Mol Cancer Res 2008;6:1268-75.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1268-1275
-
-
Virrey, J.J.1
Dong, D.2
Stiles, C.3
Patterson, J.B.4
Pen, L.5
Ni, M.6
-
8
-
-
39049160268
-
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development
-
DOI 10.1158/0008-5472.CAN-07-2950
-
Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, et al. Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Res 2008;68:498-505. (Pubitemid 351380077)
-
(2008)
Cancer Research
, vol.68
, Issue.2
, pp. 498-505
-
-
Dong, D.1
Ni, M.2
Li, J.3
Xiong, S.4
Ye, W.5
Virrey, J.J.6
Mao, C.7
Ye, R.8
Wang, M.9
Pen, L.10
Dubeau, L.11
Groshen, S.12
Hofman, F.M.13
Lee, A.S.14
-
9
-
-
79954569520
-
A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis
-
Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, et al. A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis. Cancer Res 2011;71:2848-57.
-
(2011)
Cancer Res
, vol.71
, pp. 2848-2857
-
-
Dong, D.1
Stapleton, C.2
Luo, B.3
Xiong, S.4
Ye, W.5
Zhang, Y.6
-
10
-
-
58049209726
-
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium
-
Fu Y, Wey S, Wang M, Ye R, Liao CP, Roy-Burman P, et al. Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium. Proc Natl Acad Sci USA 2008;105:19444-9.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19444-19449
-
-
Fu, Y.1
Wey, S.2
Wang, M.3
Ye, R.4
Liao, C.P.5
Roy-Burman, P.6
-
11
-
-
84862908844
-
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses pten-null leukemogenesis and AKT oncogenic signaling
-
Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, et al. Inducible knockout of GRP78/BiP in the hematopoietic system suppresses pten-null leukemogenesis and AKT oncogenic signaling. Blood 2012;119: 817-25.
-
(2012)
Blood
, vol.119
, pp. 817-825
-
-
Wey, S.1
Luo, B.2
Tseng, C.C.3
Ni, M.4
Zhou, H.5
Fu, Y.6
-
12
-
-
4544255170
-
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands
-
DOI 10.1016/j.ccr.2004.08.018, PII S1535610804002405
-
Arap MA, Lahdenranta J, Mintz PJ, Hajitou A, Sarkis AS, Arap W, et al. Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands. Cancer Cell 2004;6: 275-84. (Pubitemid 39222040)
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 275-284
-
-
Arap, M.A.1
Lahdenranta, J.2
Mintz, P.J.3
Hajitou, A.4
Sarkis, A.S.5
Arap, W.6
Pasqualini, R.7
-
14
-
-
79951537603
-
Beyond the endoplasmic reticulum: Atypical GRP78 in cell viability, signalling and therapeutic targeting
-
Ni M, Zhang Y, Lee AS. Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting. Biochem J 2011;434:181-8.
-
(2011)
Biochem J
, vol.434
, pp. 181-188
-
-
Ni, M.1
Zhang, Y.2
Lee, A.S.3
-
15
-
-
77952061607
-
Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP
-
Zhang Y, Liu R, Ni M, Gill P, Lee AS. Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP. J Biol Chem 2010;285:15065-75.
-
(2010)
J Biol Chem
, vol.285
, pp. 15065-15075
-
-
Zhang, Y.1
Liu, R.2
Ni, M.3
Gill, P.4
Lee, A.S.5
-
16
-
-
37849035474
-
GRP78 and cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth
-
Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC. GRP78 and cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth. Mol Cell Biol 2008;28:666-77.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 666-677
-
-
Shani, G.1
Fischer, W.H.2
Justice, N.J.3
Kelber, J.A.4
Vale, W.5
Gray, P.C.6
-
17
-
-
34250847014
-
Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery
-
DOI 10.1021/mp060122j
-
Liu Y, Steiniger SC, Kim Y, Kaufmann GF, Felding-Habermann B, Janda KD. Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery. Mol Pharm 2007;4:435-47. (Pubitemid 46983958)
-
(2007)
Molecular Pharmaceutics
, vol.4
, Issue.3
, pp. 435-447
-
-
Liu, Y.1
Steiniger, S.C.J.2
Kim, Y.3
Kaufmann, G.F.4
Felding-Habermann, B.5
Janda, K.D.6
-
18
-
-
77956165188
-
GRP78 signaling hub a receptor for targeted tumor therapy
-
Sato M, Yao VJ, Arap W, Pasqualini R. GRP78 signaling hub a receptor for targeted tumor therapy. Adv Genet 2010;69:97-114.
-
(2010)
Adv Genet
, vol.69
, pp. 97-114
-
-
Sato, M.1
Yao, V.J.2
Arap, W.3
Pasqualini, R.4
-
19
-
-
84877098258
-
Inhibition of established micrometastases bytargeted drug delivery via cell surface-associated GRP78
-
Miao YR, Eckhardt BL, Cao Y, Pasqualini R, Argani P, Arap W, et al. Inhibition of established micrometastases bytargeted drug delivery via cell surface-associated GRP78. Clin Cancer Res 2013;19:2107-16.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2107-2116
-
-
Miao, Y.R.1
Eckhardt, B.L.2
Cao, Y.3
Pasqualini, R.4
Argani, P.5
Arap, W.6
-
20
-
-
78650193523
-
Mouse prostate cancer cell lines established from primary and postcastration recurrent tumors
-
Liao CP, Liang M, Cohen MB, Flesken-Nikitin A, Jeong JH, Nikitin AY, et al. Mouse prostate cancer cell lines established from primary and postcastration recurrent tumors. Horm Cancer 2010;1:44-54.
-
(2010)
Horm Cancer
, vol.1
, pp. 44-54
-
-
Liao, C.P.1
Liang, M.2
Cohen, M.B.3
Flesken-Nikitin, A.4
Jeong, J.H.5
Nikitin, A.Y.6
-
21
-
-
77950577414
-
Novel EphB4 monoclonal antibodies modulate angiogenesis and inhibit tumor growth
-
Krasnoperov V, Kumar SR, Ley E, Li X, Scehnet J, Liu R, et al. Novel EphB4 monoclonal antibodies modulate angiogenesis and inhibit tumor growth. Am J Pathol 2010;176:2029-38.
-
(2010)
Am J Pathol
, vol.176
, pp. 2029-2038
-
-
Krasnoperov, V.1
Kumar, S.R.2
Ley, E.3
Li, X.4
Scehnet, J.5
Liu, R.6
-
22
-
-
34547632147
-
Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence
-
DOI 10.1158/0008-5472.CAN-07-0668
-
Liao CP, Zhong C, Saribekyan G, Bading J, Park R, Conti PS, et al. Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. Cancer Res 2007;67:7525-33. (Pubitemid 47206583)
-
(2007)
Cancer Research
, vol.67
, Issue.15
, pp. 7525-7533
-
-
Liao, C.-P.1
Zhong, C.2
Saribekyan, G.3
Bading, J.4
Park, R.5
Conti, P.S.6
Moats, R.7
Berns, A.8
Shi, W.9
Zhou, Z.10
Nikitin, A.Y.11
Roy-Burman, P.12
-
23
-
-
77649272916
-
The use of inhibitors to study endocytic pathways of gene carriers: Optimization and pitfalls
-
Vercauteren D, Vandenbroucke RE, Jones AT, Rejman J, Demeester J, De Smedt SC, et al. The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls. Mol Ther 2010;18:561-9.
-
(2010)
Mol Ther
, vol.18
, pp. 561-569
-
-
Vercauteren, D.1
Vandenbroucke, R.E.2
Jones, A.T.3
Rejman, J.4
Demeester, J.5
De Smedt, S.C.6
-
24
-
-
84887014432
-
The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells
-
Shin SY, Lee KS, Choi YK, Lim HJ, Lee HG, Lim Y, et al. The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells. Carcinogenesis 2013;34:2080-9.
-
(2013)
Carcinogenesis
, vol.34
, pp. 2080-2089
-
-
Shin, S.Y.1
Lee, K.S.2
Choi, Y.K.3
Lim, H.J.4
Lee, H.G.5
Lim, Y.6
-
25
-
-
79959870288
-
Overexpres-sion of GRP78 and GRP94 is involved in colorectal carcinogenesis
-
Takahashi H, Wang JP, Zheng HC, Masuda S, Takano Y. Overexpres-sion of GRP78 and GRP94 is involved in colorectal carcinogenesis. Histol Histopathol 2011;26:663-71.
-
(2011)
Histol Histopathol
, vol.26
, pp. 663-671
-
-
Takahashi, H.1
Wang, J.P.2
Zheng, H.C.3
Masuda, S.4
Takano, Y.5
-
26
-
-
0026503190
-
Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
-
Aslakson CJ, Miller FR. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 1992;52:1399-405.
-
(1992)
Cancer Res
, vol.52
, pp. 1399-1405
-
-
Aslakson, C.J.1
Miller, F.R.2
-
27
-
-
79951841266
-
Increased expression of P-glycoprotein is associated with doxorubicin chemore-sistance in the metastatic 4T1 breast cancer model
-
Bao L, Haque A, Jackson K, Hazari S, Moroz K, Jetly R, et al. Increased expression of P-glycoprotein is associated with doxorubicin chemore-sistance in the metastatic 4T1 breast cancer model. Am J Pathol 2011;178:838-52.
-
(2011)
Am J Pathol
, vol.178
, pp. 838-852
-
-
Bao, L.1
Haque, A.2
Jackson, K.3
Hazari, S.4
Moroz, K.5
Jetly, R.6
-
28
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
DOI 10.1038/nature04703, PII NATURE04703
-
Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, Wu H, et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 2006;441:475-82. (Pubitemid 44050144)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
Morrison, S.J.7
-
29
-
-
84866984516
-
A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death
-
Maddalo D, Neeb A, Jehle K, Schmitz K, Muhle-Goll C, Shatkina L, et al. A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death. PLoS One 2012;7:e45690.
-
(2012)
PLoS One
, vol.7
-
-
Maddalo, D.1
Neeb, A.2
Jehle, K.3
Schmitz, K.4
Muhle-Goll, C.5
Shatkina, L.6
-
30
-
-
41149140928
-
A new tumor-specific variant of GRP78 as target for antibody-based therapy
-
DOI 10.1038/labinvest.2008.2, PII LABINVEST20082
-
Rauschert N, Brandlein S, Holzinger E, Hensel F, Muller-Hermelink HK, Vollmers HP. A new tumor-specific variant of GRP78 as target for antibody-based therapy. Lab Invest 2008;88:375-86. (Pubitemid 351432774)
-
(2008)
Laboratory Investigation
, vol.88
, Issue.4
, pp. 375-386
-
-
Rauschert, N.1
Brandlein, S.2
Holzinger, E.3
Hensel, F.4
Muller-Hermelink, H.-K.5
Vollmers, H.P.6
-
31
-
-
0036828823
-
2-macroglobulin-induced signal transduction: Evidence from RNA interference that the low density lipoprotein receptor-related protein is associated with, but not necessary for, GRP 78-mediated signal transduction
-
DOI 10.1074/jbc.M206174200
-
Misra UK, Gonzalez-Gronow M, Gawdi G, Hart JP, Johnson CE, Pizzo SV. The role of grp 78 in alpha 2-macroglobulin-induced signal trans-duction. evidence from RNA interference that the low density lipopro-tein receptor-related protein is associated with, but not necessary for, GRP 78-mediated signal transduction. J Biol Chem 2002;277: 42082-7. (Pubitemid 35257523)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.44
, pp. 42082-42087
-
-
Misra, U.K.1
Gonzalez-Gronow, M.2
Gawdi, G.3
Hart, J.P.4
Johnson, C.E.5
Pizzo, S.V.6
-
32
-
-
84871271221
-
Receptor-recognized alpha(2)-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells
-
Misra UK, Pizzo SV. Receptor-recognized alpha(2)-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells. PLoS One 2012;7:e51735.
-
(2012)
PLoS One
, vol.7
-
-
Misra, U.K.1
Pizzo, S.V.2
-
33
-
-
84860778806
-
A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice
-
de Ridder GG, Ray R, Pizzo SV. A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice. Melanoma Res 2012;22:225-35.
-
(2012)
Melanoma Res
, vol.22
, pp. 225-235
-
-
De Ridder, G.G.1
Ray, R.2
Pizzo, S.V.3
-
34
-
-
11344268358
-
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor
-
Camp ER, Summy J, Bauer TW, Liu W, Gallick GE, Ellis LM. Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor. Clin Cancer Res 2005;11:397-405. (Pubitemid 40075820)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.1
, pp. 397-405
-
-
Camp, E.R.1
Summy, J.2
Bauer, T.W.3
Liu, W.4
Gallick, G.E.5
Ellis, L.M.6
|