Effects of dehydroepiandrosterone on in vivo ovine follicular development

Human Reproduction

Volumn 29, Issue 1, 2014, Pages 146-154

  Narkwichean, A ^a,b   Jayaprakasan, K ^a,c   Maalouf, W E ^a   Hernandez Medrano, J H ^a   Pincott Allen, C ^a   Campbell, B K ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b SRINAKHARINWIROT UNIVERSITY   (Thailand)

^c ROYAL DERBY HOSPITAL   (United Kingdom)

Author keywords

Dehydroepiandrosterone; Diminished ovarian reserve; In vitro fertilization; Ovarian follicular development (folliculogenesis)

Indexed keywords

GONADOTROPIN; MUELLERIAN INHIBITING FACTOR; PRASTERONE;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; FEMALE; FERTILIZATION IN VITRO; GRANULOSA CELL; HISTOLOGY; HORMONAL REGULATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; NONHUMAN; OVARIAN RESERVE; OVARY; OVARY FOLLICLE; OVARY FOLLICLE CELL; OVARY FOLLICLE DEVELOPMENT; OVINE MODEL; PREGNANCY; PROTEIN EXPRESSION; SHEEP;

ANIMALIA; OVIS; OVIS ARIES;

DEHYDROEPIANDROSTERONE; DIMINISHED OVARIAN RESERVE; IN VITRO FERTILIZATION; OVARIAN FOLLICULAR DEVELOPMENT (FOLLICULOGENESIS);

ANIMALS; ANTI-MULLERIAN HORMONE; AUTOGRAFTS; DEHYDROEPIANDROSTERONE; DRUG IMPLANTS; FEMALE; OVARIAN FOLLICLE; OVARY; PREGNANCY; SHEEP, DOMESTIC;

EID: 84890698507     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/det408     Document Type: Article

References (44)

1. Barad D, Brill H, Gleicher N. Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function. J Assist Reprod Genet 2007;24:629-634.
2. Broekmans FJ, Kwee J, Hendriks DJ, Mol BW, Lambalk CB. A systematic review of tests predicting ovarian reserve and IVF outcome. Hum Reprod Update 2006;12:685-718.
3. Campbell BK, Souza C, Gong J, Webb R, Kendall N, Marsters P, Robinson G, Mitchell A, Telfer EE, Baird DT. Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans. Reprod Suppl 2003;61:429-443.
4. Campbell BK, Telfer EE, Webb R, Baird DT. Evidence of a role for follicle-stimulating hormone in controlling the rate of preantral follicle development in sheep. Endocrinology 2004;145:1870-1879.
5. Campbell BK, Clinton M, Webb R. The role of anti-Mullerian hormone (AMH) during follicle development in a monovulatory species (sheep). Endocrinology 2012;153:4533-4543.
6. Casson PR, Santoro N, Elkind-Hirsch K, Carson SA, Hornsby PJ, Abraham G, Buster JE. Postmenopausal dehydroepiandrosterone administration increases free insulin-like growth factor-I and decreases high-density lipoprotein: a six-month trial. Fertil Steril 1998;70:107-110.
7. Dorfman R, Shipley R. Androgens. New York: John Wiley and Sons, 1956.
8. Durlinger AL, Gruijters MJ, Kramer P, Karels B, Ingraham HA, NachtigalMW, Uilenbroek JT, Grootegoed JA, Themmen AP. Anti-Mullerian hormone inhibits initiation of primordial follicle growth in the mouse ovary. Endocrinology 2002a;143:1076-1084.
9. Durlinger AL, Visser JA, Themmen AP. Regulation of ovarian function: the role of anti-Mullerian hormone. Reproduction 2002b;124:601-609.
10. Ehrmann DA. Polycystic ovary syndrome. N Engl J Med 2005; 352:1223-1236.
11. Franks S, Stark J, Hardy K. Follicle dynamics and anovulation in polycystic ovary syndrome. Hum Reprod Update 2008;14:367-378.
12. Freeman SB, Yang Q, Allran K, Taft LF, Sherman SL. Women with a reduced ovarian complement may have an increased risk for a child with Down syndrome. Am J Hum Genet 2000;66:1680-1683.
13. Gleicher N, Weghofer A, Barad DH. Dehydroepiandrosterone (DHEA) reduces embryo aneuploidy: direct evidence from preimplantation genetic screening (PGS). Reprod Biol Endocrinol 2010a;8:140.
14. Gleicher N, Weghofer A, Barad DH. Improvement in diminished ovarian reserve after dehydroepiandrosterone supplementation. Reprod Biomed Online 2010b;21:360-365.
15. Gougeon A. Ovarian follicular growth in humans: ovarian ageing and population of growing follicles. Maturitas 1998;30:137-142.
16. Gougeon A, Ecochard R, Thalabard JC. Age-related changes of the population of human ovarian follicles: increase in the disappearance rate of non-growing and early-growing follicles in aging women. Biol Reprod 1994;50:653-663.
17. Hillier SG, Tetsuka M, Fraser HM. Location and developmental regulation of androgen receptor in primate ovary. Hum Reprod 1997;12:107-111.
18. Hornsby PJ. Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline. Ann N Y Acad Sci 1995;774:29-46.
19. HuYC, Wang PH, Yeh S, Wang RS, Xie C, XuQ, Zhou X, ChaoHT, TsaiMY, Chang C. Subfertility and defective folliculogenesis in female mice lacking androgen receptor. Proc Natl Acad Sci USA 2004;101:11209-11214.
20. Juengel JL, Heath DA, Quirke LD, McNatty KP. Oestrogen receptor alpha and beta, androgen receptor and progesterone receptor mRNA and protein localisation within the developing ovary and in small growing follicles of sheep. Reproduction 2006;131:81-92.
21. Leong M, Patrizio P. Poor Responders: How to Define, Diagnose and Treat? 2010. http://www. ivf-worldwide. com/survey/survey-poor-responders. html.
22. Li H, Simpson ER, Liu JP. Oestrogen, telomerase, ovarian ageing and cancer. Clin Exp Pharmacol Physiol 2010;37:78-82.
23. Longcope C. Adrenal and gonadal androgen secretion in normal females. Clin Endocrinol Metab 1986;15:213-228.
24. Lundy T, Smith P, O'Connell A, Hudson NL, McNatty KP. Populations of granulosa cells in small follicles of the sheep ovary. J Reprod Fertil 1999; 115:251-262.
25. McNatty KP, Heath DA, Lundy T, Fidler AE, Quirke L, O'Connell A, Smith P, Groome N, Tisdall DJ. Control of early ovarian follicular development. J Reprod Fertil Suppl 1999;54:3-16.
26. McNatty KP, Fidler AE, Juengel JL, Quirke LD, Smith PR, Heath DA, Lundy T, O'Connell A, Tisdall DJ. Growth and paracrine factors regulating follicular formation and cellular function. Mol Cell Endocrinol 2000;163:11-20.
27. Menken J, Trussell J, Larsen U. Age and infertility. Science 1986; 233:1389-1394.
28. Narkwichean A, Maalouf W, Campbell BK, Jayaprakasan K. Efficacy of dehydroepiandrosterone to improve ovarian response in women with diminished ovarian reserve: a meta-analysis. Reprod Biol Endocrinol 2013; 11:44.
29. Onions VJ, Webb R, McNeilly AS, Campbell BK. Ovarian endocrine profile and long-term vascular patency following heterotopic autotransplantation of cryopreserved whole ovine ovaries. Hum Reprod 2009; 24:2845-2855.
30. Onions VJ, Webb R, Pincott-Allen C, PictonHM, Campbell BK. The effects of whole ovarian perfusion and cryopreservation on endothelial cell-related gene expression in the ovarian medulla and pedicle. MolHumReprod 2013; 19:205-215.
31. Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol 2000;182:311-322.
32. Shiina H, Matsumoto T, Sato T, Igarashi K, Miyamoto J, Takemasa S, Sakari M, Takada I, Nakamura T, Metzger D et al. Premature ovarian failure in androgenreceptor-deficientmice. ProcNatl AcadSciUSA2006;103:224-229.
33. Speroff L, Fritz M. Clinical Gynecologic Endocrinology and Infertility, 7 edn. Philadelphia: Lippincott Williams & Wilkin, 2005.
34. Stubbs SA, Hardy K, Da Silva-Buttkus P, Stark J, Webber LJ, Flanagan AM, Themmen AP, Visser JA, Groome NP, Franks S. Anti-mullerian hormone protein expression is reduced during the initial stages of follicle development in human polycystic ovaries. J Clin Endocrinol Metab 2005; 90:5536-5543.
35. Templeton A, Morris JK, ParslowW. Factors that affect outcome of in-vitro fertilisation treatment. Lancet 1996;348:1402-1406.
36. The Animal (Scientific Procedures) Act 1986.
37. The Animal (Scientific Procedures) Act 1986 Amendment Regulations 2012.
38. In House of Commons Stationery Office (ed), 2013.
39. TroutSW, Seifer DB. Do women with unexplained recurrent pregnancy loss have higher day 3 serum FSH and estradiol values? Fertil Steril 2000; 74:335-337.
40. Vermeulen A. Dehydroepiandrosterone sulfate and aging. Ann N Y Acad Sci 1995;774:121-127.
41. Walters KA, Allan CM, Jimenez M, Lim PR, Davey RA, Zajac JD, Illingworth P, Handelsman DJ. Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility. Endocrinology 2007;148:3674-3684.
42. Walters KA, Allan CM, Handelsman DJ. Androgen actions and the ovary. Biol Reprod 2008;78:380-389.
43. Weenen C, Laven JS, Von Bergh AR, Cranfield M, Groome NP, Visser JA, Kramer P, Fauser BC, Themmen AP. Anti-Mullerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod 2004;10:77-83.
44. Wiser A, Gonen O, Ghetler Y, Shavit T, Berkovitz A, Shulman A. Addition of dehydroepiandrosterone (DHEA) for poor-responder patients before and during IVF treatment improves the pregnancy rate: a randomized prospective study. Hum Reprod 2010;25:2496-2500.