New Delhi metallo-β-lactamase-producing Acinetobacter baumannii: A novel paradigm for spreading antibiotic resistance genes

Future Microbiology

Volumn 9, Issue 1, 2014, Pages 33-41

  Bonnin, Rémy A ^a   Poirel, Laurent ^a,b   Nordmann, Patrice ^a,b  

^a Associated French National Reference Center for Antibiotic Resistance: Carbapenemase producing Enterobacteriaceae   (France)

^b University of Fribourg   (Switzerland)

Author keywords

lactamase; antibiotic resistance; carbapenemase; Gram negative rods

Indexed keywords

CARBAPENEMASE; EXTENDED SPECTRUM BETA LACTAMASE; METALLO BETA LACTAMASE;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ARTICLE; ENTEROBACTERIACEAE; GENETIC VARIABILITY; INDIA; KLEBSIELLA PNEUMONIAE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

ACINETOBACTER BAUMANNII; BETA-LACTAMASES; DNA TRANSPOSABLE ELEMENTS; DRUG RESISTANCE, BACTERIAL; EVOLUTION, MOLECULAR; GENE ORDER; GENE TRANSFER, HORIZONTAL; RECOMBINATION, GENETIC; SYNTENY;

EID: 84890594494     PISSN: 17460913     EISSN: 17460921     Source Type: Journal    
DOI: 10.2217/fmb.13.69     Document Type: Article

References (48)

1. Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: Emergence of a successful pathogen. Clin. Microbiol. Rev. 21(3), 538-582 (2008).
2. Poirel L, Bonnin RA, Nordmann P. Genetic basis of antibiotic resistance in pathogenic Acinetobacter species. IUBMB Life 63(12), 1061-1067 (2011).
3. Fishbain J, Peleg AY. Treatment of Acinetobacter infections. Clin. Infect. Dis. 51(1), 79-84 (2010).
4. Poirel L, Bonnin RA, Nordmann P. Genetic support and diversity of acquired extended-spectrum b-lactamases in Gram-negative rods. Infect. Genet. Evol. 12(5), 883-893 (2012).
5. Fournier PE, Vallenet D, Barbe V et al. Comparative genomics of multidrug resistance in Acinetobacter Baumannii. PLoS Genet. 2(1), e7 (2006).
6. Iacono M, Villa L, Fortini D et al. Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group. Antimicrob. Agents Chemother. 52(7), 2616-2625 (2008).
7. Poirel L, Naas T, Nordmann P. Diversity, epidemiology, and genetics of class D b-lactamases. Antimicrob. Agents Chemother. 54(1), 24-38 (2010).
8. Higgins PG, Perez-Llarena FJ, Zander E et al. OXA-235, a novel class D b-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. Antimicrob. Agents Chemother. 57(5), 2121-2126 (2013).
9. Poirel L, Figueiredo S, Cattoir V, Carattoli A, Nordmann P. Acinetobacter radioresistens as a silent source of carbapenem resistance for Acinetobacter spp. Antimicrob. Agents Chemother. 52(4), 1252-1256 (2008).
10. Kumarasamy KK, Toleman MA, Walsh TR et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: A molecular, biological, and epidemiological study. Lancet Infect. Dis. 10(9), 597-602 (2010).
11. Nordmann P, Poirel L, Walsh TR, Livermore DM. The emerging NDM carbapenemases. Trends Microbiol. 19(12), 588-595 (2011).
12. Yong D, Toleman MA, Giske CG et al. Characterization of a new metallo-b-lactamase gene, blaNDM 1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob. Agents Chemother. 53(12), 5046-5054 (2009).
13. Walsh TR, Weeks J, Livermore DM, Toleman MA. Dissemination of NDM 1 positive bacteria in the New Delhi environment and its implications for human health: An environmental point prevalence study. Lancet Infect. Dis. 11(5), 355-362 (2011).
14. Poirel L, Bonnin RA, Nordmann P. Analysis of the resistome of a multidrug-resistant NDM 1-producing Escherichia coli strain by high-Throughput genome sequencing. Antimicrob. Agents Chemother. 55(9), 4224-4229 (2011).
15. Mussi MA, Limansky AS, Viale AM. Acquisition of resistance to carbapenems in multidrug-resistant clinical strains of Acinetobacter baumannii: Natural insertional inactivation of a gene encoding a member of a novel family of b-barrel outer membrane proteins. Antimicrob. Agents Chemother. 49(4), 1432-1440 (2005).
16. Lopes BS, Amyes SG. Role of ISAba1 and ISAba125 in governing the expression of blaADC in clinically relevant Acinetobacter baumannii strains resistant to cephalosporins. J. Med. Microbiol. 61(Pt 8), 1103-1108 (2012).
17. Bonnin RA, Poirel L, Carattoli A, Nordmann P. Characterization of an IncFII plasmid encoding NDM 1 from Escherichia coli ST131. PLoS ONE 7(4), e34752 (2012).
18. Bonnin RA, Poirel L, Naas T et al. Dissemination of New Delhi metallo-b-lactamase-1-producing Acinetobacter baumannii in Europe. Clin. Microbiol. Infect. 18(9), e362-e365 (2012).
19. Poirel L, Bonnin RA, Boulanger A et al. Tn125-related acquisition of blaNDM like genes in Acinetobacter baumannii. Antimicrob. Agents Chemother. 56(2), 1087-1089 (2012).
20. Dortet L, Nordmann P, Poirel L. Association of the emerging carbapenemase NDM 1 with a bleomycin resistance protein in Enterobacteriaceae and Acinetobacter baumannii. Antimicrob. Agents Chemother. 56(4), 1693-1697 (2012).
21. Naas T, Namdari F, Bogaerts P et al. Genetic structure associated with blaOXA-18, encoding a clavulanic acid-inhibited extended-spectrum oxacillinase. Antimicrob. Agents Chemother. 52(11), 3898-3904 (2008).
22. Toleman MA, Bennett PM, Walsh TR. ISCR elements: Novel gene-capturing systems of the 21st century?. Microbiol. Mol. Biol. Rev. 70(2), 296-316 (2006).
23. Toleman MA, Spencer J, Jones L, Walsh TR. blaNDM 1 is a chimera likely constructed in Acinetobacter baumannii. Antimicrob. Agents Chemother. 56(5), 2773-2776 (2012).
24. Bonnet R, Marchandin H, Chanal C et al. Chromosome-encoded class D b-lactamase OXA-23 in Proteus mirabilis. Antimicrob. Agents Chemother. 46(6), 2004-2006 (2002).
25. Mammeri H, Poirel L, Mangeney N, Nordmann P. Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to b-lactams. Antimicrob. Agents Chemother. 47(5), 1536-1542 (2003).
26. Karthikeyan K, Thirunarayan MA, Krishnan P. Coexistence of blaOXA-23 with blaNDM 1 and armA in clinical isolates of Acinetobacter baumannii from India. J. Antimicrob. Chemother. 65(10), 2253-2254 (2010).
27. Chen Y, Zhou Z, Jiang Y, Yu Y. Emergence of NDM 1-producing Acinetobacter baumannii in China. J. Antimicrob. Chemother. 66(6), 1255-1259 (2011).
28. Fu Y, Du X, Ji J et al. Epidemiological characteristics and genetic structure of blaNDM 1 in non-baumannii Acinetobacter spp. in China. J. Antimicrob. Chemother. 67(9), 2114-2122 (2012).
29. Wang Y, Wu C, Zhang Q et al. Identification of New Delhi metallo-b-lactamase 1 in Acinetobacter lwoffii of food animal origin. PLoS ONE 7(5), e37152 (2012).
30. Zong Z, Zhang X. blaNDM 1-carrying Acinetobacter johnsonii detected in hospital sewage. J. Antimicrob. Chemother. 68(5), 1007-1010 (2013).
31. Diancourt L, Passet V, Nemec A, Dijkshoorn L, Brisse S. The population structure of Acinetobacter baumannii: Expanding multiresistant clones from an ancestral susceptible genetic pool. PLoS ONE 5(4), e10034 (2010).
32. Bonnin RA, Cuzon G, Poirel L, Nordmann P. Multidrug-resistant Acinetobacter baumannii clone, France. Emerg. Infect. Dis. 19(5), 822-823 (2013).
33. Kaase M, Nordmann P, Wichelhaus TA et al. NDM 2 carbapenemase in Acinetobacter baumannii from Egypt. J. Antimicrob. Chemother. 66(6), 1260-1262 (2011).
34. Espinal P, Fugazza G, Lopez Y et al. Dissemination of an NDM 2-producing Acinetobacter baumannii clone in an Israeli rehabilitation center. Antimicrob. Agents Chemother. 55(11), 5396-5398 (2011).
35. Ghazawi A, Sonnevend A, Bonnin RA et al. NDM 2 carbapenemase-producing Acinetobacter baumannii in the United Arab Emirates. Clin. Microbiol. Infect. 18(2), e34-e36 (2012).
36. Bartual SG, Seifert H, Hippler C et al. Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J. Clin. Microbiol. 43(9), 4382-4390 (2005).
37. Kramer A, Schwebke I, Kampf G. How long do nosocomial pathogens persist on inanimate surfaces?. A systematic review. BMC Infect. Dis. 6, 130 (2006).
38. Adams MD, Goglin K, Molyneaux N et al. Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii. J. Bacteriol. 190(24), 8053-8064 (2008).
39. Zanetti G, Blanc DS, Federli I et al. Importation of Acinetobacter baumannii into a burn unit: A recurrent outbreak of infection associated with widespread environmental contamination. Infect. Control Hosp. Epidemiol. 28(6), 723-725 (2007).
40. Krizova L, Bonnin RA, Nordmann P, Nemec A, Poirel L. Characterization of a multidrug-resistant Acinetobacter baumannii strain carrying the blaNDM 1 and blaOXA-23 carbapenemase genes from the Czech Republic. J. Antimicrob. Chemother. 67(6), 1550-1552 (2012).
41. Gottig S, Pfeifer Y, Wichelhaus TA et al. Global spread of New Delhi metallo-b-lactamase 1. Lancet Infect. Dis. 10(12), 828-829 (2010).
42. Bogaerts P, Rezende de Castro R, Roisin S et al. Emergence of NDM 1-producing Acinetobacter baumannii in Belgium. J. Antimicrob. Chemother. 67(6), 1552-1553 (2012).
43. Nakazawa Y, Ii R, Tamura T et al. A case of NDM 1-producing Acinetobacter baumannii transferred from India to Japan. J. Infect. Chemother. 19(2), 330-332 (2013).
44. Hu Y, Zhang W, Liang H et al. Whole-genome sequence of a multidrug-resistant clinical isolate of Acinetobacter lwoffii. J. Bacteriol. 193(19), 5549-5550 (2011).
45. Chen Y, Cui Y, Pu F et al. Draft genome sequence of an Acinetobacter genomic species 3 strain harboring a blaNDM 1 gene. J. Bacteriol. 194(1), 204-205 (2012).
46. Zhou Z, Guan R, Yang Y et al. Identification of New Delhi metallo-b-lactamase gene (NDM 1) from a clinical isolate of Acinetobacter junii in China. Can. J. Microbiol. 58(1), 112-115 (2012).
47. Yang J, Chen Y, Jia X et al. Dissemination and characterization of NDM 1-producing Acinetobacter pittii in an intensive care unit in China. Clin. Microbiol. Infect. 18(12), e506-e513 (2013).
48. Carattoli A, Villa L, Poirel L, Bonnin RA, Nordmann P. Evolution of IncA/C blaCMY-2-carrying plasmids by acquisition of the blaNDM 1 carbapenemase gene. Antimicrob. Agents Chemother. 56(2), 783-786 (2012).