Rates and risk of hospitalisation among patients with type 2 diabetes: Retrospective cohort study using the UK General Practice Research Database linked to English Hospital Episode Statistics

International Journal of Clinical Practice

Volumn 68, Issue 1, 2014, Pages 40-48

  Khalid, J M ^a   Raluy Callado, M ^a   Curtis, B H ^b   Boye, K S ^b   Maguire, A ^a   Reaney, M ^c  

^a EVIDERA   (United Kingdom)

^b ELI LILLY AND COMPANY   (United States)

^c Global Health Outcomes   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIGUANIDE; CHOLESTEROL; HEMOGLOBIN A1C; LONG ACTING INSULIN; SULFONYLUREA DERIVATIVE;

ADULT; AGE; AGED; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CHRONIC KIDNEY FAILURE; COHORT ANALYSIS; COMORBIDITY; FEMALE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; HYPOGLYCEMIA; INSULIN TREATMENT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEX DIFFERENCE; UNITED KINGDOM; DIABETES MELLITUS, TYPE 2; ENGLAND; MIDDLE AGED; PROGNOSIS; STATISTICS AND NUMERICAL DATA;

DIABETES MELLITUS, TYPE 2; ENGLAND; EPIDEMIOLOGIC METHODS; FEMALE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PROGNOSIS;

EID: 84890550292     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/ijcp.12265     Document Type: Article

References (51)

1. Kasper D, Braunwald E, Hauser S, et al. Harrison's Principles of Internal Medicine. 16th edn. New York: McGraw-Hill Professional Publishers, 2004.
2. Whiting DR, Guariguata L, Weil C, et al. Diabetes Research and clinical practice IDF Diabetes Atlas: International Diabetes Federation, Brussels. Australia; Belgium: Baker IDI Heart and Diabetes Institute, 2011.
3. Diabetes in the UK (April 2012)-Diabetes UK. http://www.diabetes.org.uk/ Professionals/Publications-reports-and-resources/Reports-statistics-and-case- studies/Reports/Diabetes-in-the-UK-2012/ (accessed 29 June 2012).
4. American Diabetes Association. Standards of medical care in diabetes-2012. Diabetes Care 2012; 35 (Suppl. 1): S11-63.
5. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 1993; 329: 977-86.
6. UKPDS group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998; 352: 837-53.
7. Gaede P, Vedel P, Larsen N, et al. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med 2003; 348: 383-93.
8. Shichiri M, Kishikawa H, Ohkubo Y, et al. Long-term results of the Kumamoto Study on optimal diabetes control in type 2 diabetic patients. Diabetes Care 2000; 23 (Suppl. 2): B21-9.
9. Srinivasan BT, Jarvis J, Khunti K, et al. Recent advances in the management of type 2 diabetes mellitus: a review. Postgrad Med J 2008; 84: 524-31.
10. Dawson KG, Gomes D, Gerstein H, et al. The economic cost of diabetes in Canada, 1998. Diabetes Care 2002; 25: 1303-7.
11. Simpson SH, Corabian P, Jacobs P, et al. The cost of major comorbidity in people with diabetes mellitus. CMAJ 2003; 168: 1661-7.
12. Zimmet P,. The burden of type 2 diabetes: are we doing enough? Diabetes Metab 2003; 29: 6S9-18.
13. National Collaborating Centre for Chronic Conditions (UK). Type 2 Diabetes: National Clinical Guideline for Management in Primary and Secondary Care. London: Royal College of Physicians, 2008.
14. Holmes J, Gear E, Bottomley J, et al. Do people with type 2 diabetes and their carers lose income? (T2ARDIS-4). Health Policy 2003; 64: 291-6.
15. Hex N, Bartlett C, Wright D, et al. Estimating the current and future costs of type 1 and type 2 diabetes in the UK, including direct health costs and indirect societal and productivity costs. Diabet Med 2012; 29: 855-62.
16. Holman RR, Paul SK, Bethel MA, et al. 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 2008; 359: 1577-89.
17. Pouwer F, Hermanns N,. Insulin therapy and quality of life. A review. Diabetes Metab Res Rev 2009; 25 (Suppl. 1): S4-10.
18. Odegard PS, Capoccia K,. Medication taking and diabetes: a systematic review of the literature. Diabetes Educ 2007; 33: 1014-29; discussion 30-1.
19. Quilliam BJ, Simeone JC, Ozbay AB,. Risk factors for hypoglycemia-related hospitalization in patients with type 2 diabetes: a nested case-control study. Clin Ther 2011; 33: 1781-91.
20. Supporting people and integration with long term conditions: an NHS and Social Care Model to support local innovation. Department of Health, http://www.dh.gov.uk/prod-consum-dh/groups/dh-digitalassets/@dh/@en/documents/ digitalasset/dh-4122574.pdf (accessed 20 June, 2012).
21. Moss SE, Klein R, Klein BE,. Risk factors for hospitalization in people with diabetes. Arch Intern Med 1999; 159: 2053-7.
22. Simmons D, Wenzel H,. Diabetes inpatients: a case of lose, lose, lose. Is it time to use a 'diabetes-attributable hospitalization cost' to assess the impact of diabetes? Diabet Med 2011; 28: 1123-30.
23. Williams DR, Anthony P, Young RJ, et al. Interpreting hospital admissions data across the Korner divide: the example of diabetes in the north western region. Diabet Med 1994; 11: 166-9.
24. Clinical Practice Research Datalink (CPRD), http://www.cprd.com/intro.asp (accessed 20 June, 2012).
25. Lawrenson R, Williams T, Farmer R,. Clinical information for research; the use of general practice databases. J Public Health Med 1999; 21: 299-304.
26. Hospital episode statistics, http://www.hesonline.nhs.uk (accessed 14 May, 2012).
27. Benson T,. The history of the Read Codes: the inaugural James Read Memorial Lecture 2011. Inform Prim Care 2011; 19: 173-82.
28. Donnan PT, Leese GP, Morris AD, et al. Hospitalizations for people with type 1 and type 2 diabetes compared with the nondiabetic population of Tayside, Scotland: a retrospective cohort study of resource use. Diabetes Care 2000; 23: 1774-9.
29. Cleves M, Gould W, Gutierrez RG, et al. An Introduction to Survival Analysis Using Stata, 3rd edn. College Station, TX: Stata Press, 2010.
30. Quality and Outcomes Framework (QOF). Department of Health, http://webarchive.nationalarchives.gov.uk/+/www.dh.gov.uk/en/Healthcare/ Primarycare/Primarycarecontracting/QOF/index.htm (accessed 20 June, 2012).
31. Bo S, Ciccone G, Grassi G, et al. Patients with type 2 diabetes had higher rates of hospitalization than the general population. J Clin Epidemiol 2004; 57: 1196-201.
32. Aro S, Kangas T, Reunanen A, et al. Hospital use among diabetic patients and the general population. Diabetes Care 1994; 17: 1320-9.
33. De Berardis G, D'Ettorre A, Graziano G, et al. The burden of hospitalization related to diabetes mellitus: a population-based study. Nutri Metab Cardiovasc Dis 2012; 22: 605-12.
34. Davis TM, Brown SG, Jacobs IG, et al. Determinants of severe hypoglycemia complicating type 2 diabetes: the Fremantle diabetes study. J Clin Endocrinol Metab 2010; 95: 2240-7.
35. Asuncion MM, Shaheen M, Ganesan K, et al. Increase in hypoglycemic admissions: California hospital discharge data. Ethn Dis 2007; 17: 536-40.
36. Service FJ,. Hypoglycemic disorders. N Engl J Med 1995; 332: 1144-52.
37. Schejter YD, Turvall E, Ackerman Z,. Characteristics of patients with sulphonurea-induced hypoglycemia. J Am Med Dir Assoc 2012; 13: 234-8.
38. Mäkimattila S, Korhonen P, Haukka J, et al. Type of insulin and age are predictors of hospitalization due to severe hypoglycemia: the EpiHypo Study. Berlin, Germany: European Association for the Study of Diabetes (EASD), 2012.
39. van Staa T, Abenhaim L, Monette J,. Rates of hypoglycemia in users of sulfonylureas. J Clin Epidemiol 1997; 50: 735-41.
40. Ray NF, Thamer M, Taylor T, et al. Hospitalization and expenditures for the treatment of general medical conditions among the U.S. diabetic population in 1991. J Clin Endocrinol Metab 1996; 81: 3671-9.
41. Aro S, Koivisto VA, Reunanen A, et al. Influence of morbidity and health care structure on hospitalization among adult diabetic patients. Diabet Med 1996; 13: 376-81.
42. Lee CH, Tey BH, Chew W,. Epidemiology of diabetes mellitus in a regional hospital medical unit. Ann Acad Med Singapore 1993; 22: 864-9.
43. Rosenthal MJ, Fajardo M, Gilmore S, et al. Hospitalization and mortality of diabetes in older adults. A 3-year prospective study. Diabetes Care 1998; 21: 231-5.
44. Panser LA, Naessens JM, Nobrega FT, et al. Utilization trends and risk factors for hospitalization in diabetes mellitus. Mayo Clin Proc 1990; 65: 1171-84.
45. Goyder E, Spiers N, McNally P, et al. Do diabetes clinic attendees stay out of hospital? A matched case-control study. Diabet Med 1999; 16: 687-91.
46. Roesler J, Bishop D, Walseth J,. Economic cost of diabetes mellitus-Minnesota, 1988. MMWR Morb Mortal Wkly Rep 1991; 40: 229-31.
47. NICE. Preventing type 2 diabetes: risk identification and interventions for individuals at high risk. Issued: July 2012, NICE public health guidance 38.
48. Guo JJ, Gibson JT, Gropper DM, et al. Empiric investigation on direct costs-of-illness and healthcare utilization of Medicaid patients with diabetes mellitus. Am J Manag Care 1998; 4: 1433-46.
49. Ashton CM, Septimus J, Petersen NJ, et al. Healthcare use by veterans treated for diabetes mellitus in the Veterans Affairs medical care system. Am J Manag Care 2003; 9: 145-50.
50. Gray A, Raikou M, McGuire A, et al. Cost effectiveness of an intensive blood glucose control policy in patients with type 2 diabetes: economic analysis alongside randomised controlled trial (UKPDS 41). United Kingdom Prospective Diabetes Study Group. BMJ 2000; 320: 1373-8.
51. Khan NF, Harrison SE, Rose PW,. Validity of diagnostic coding within the General Practice Research Database: a systematic review. Br J Gen Pract 2010; g 60: e128-36.