Systematic review with meta-analysis: Clinical manifestations and management of autoimmune hepatitis in the elderly

Alimentary Pharmacology and Therapeutics

Volumn 39, Issue 2, 2014, Pages 117-124

  Chen, J ^a   Eslick, G D ^b   Weltman, M ^a  

^a NEPEAN HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; AZATHIOPRINE; CORTICOSTEROID; GLUCOCORTICOID; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN; METHYLPREDNISOLONE; PREDNISOLONE; PREDNISONE; SMOOTH MUSCLE ANTIBODY;

ANTIBODY DETECTION; AUTOIMMUNE HEPATITIS; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; DRUG RESPONSE; DRUG TREATMENT FAILURE; HAPLOTYPE; HISTOPATHOLOGY; HUMAN; LIVER CIRRHOSIS; META ANALYSIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RELAPSE; REMISSION; REVIEW; SEROLOGY; SYSTEMATIC REVIEW;

AGED; GLUCOCORTICOIDS; HAPLOTYPES; HEPATITIS, AUTOIMMUNE; HLA-DR3 ANTIGEN; HLA-DR4 ANTIGEN; HUMANS; LIVER CIRRHOSIS; LIVER FUNCTION TESTS; RETROSPECTIVE STUDIES;

EID: 84890547175     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/apt.12563     Document Type: Review

References (30)

1. Johnson PJ, McFarlane IG,. Meeting report: international autoimmune hepatitis group. Hepatology 1993; 18: 998-1005.
2. Alvarez F, Berg PA, Bianchi FB, et al,. International autoimmune hepatitis group report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999; 31: 929-38.
3. Lamers MM, van Oijen MG, Pronk M, Drenth JP,. Treatment options for autoimmune hepatitis: a systematic review of randomized controlled trials. J Hepatol 2010; 53: 191-8.
4. Waldenstrom J,. Leber, Bluetproteine und Nahrungseiweiss Stoffwechsel Krankheiten, Sonderband. 8(XV). Bad Kissingen: Tagung, 1950.
5. Kunkel HG, Ahrens JR, Eisenmenger WJ, Bougiovanni AM, Slater RJ,. Extreme hypergammaglobulinaemia in young women with liver disease of unknown aetiology. J Clin Invest 1951; 30: 654.
6. Bearn AG, Kunkel HG, Slater RJ,. The problem of chronic liver disease in young women. Am J Med 1956; 21: 3-15.
7. Lee YM, Teo EK, Ng TM,. Autoimmune hepatitis in Singapore: a rare syndrome affecting middle-aged women. J Gastroen Hepatol 2001; 16: 1384-9.
8. Ngu JH, Bechly K, Chapman BA, et al,. Population-based epidemiology study of autoimmune hepatitis: a disease of older women? J Gastroen Hepatol 2010; 25: 1681-6.
9. Abe M, Mashiba T, Zeniya M, Yamamoto K, Onji M, Tsubouchi H,. Present status of autoimmune hepatitis in Japan: a nationwide survey. J Gastroenterol 2011; 46: 1136-41.
10. Moher D, Liberati A, Tetzlaff J, Altman DG, and the PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009; 151: 264-9.
11. DerSimonian R, Laird N,. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88.
12. Higgins JP, Thompson SG, Deeks JJ, Altman DG,. Measuring inconsistency in meta-analysis. Brit Med J 2003; 327: 557-60.
13. Egger M, Davey S, Schneider M, Minder C,. Bias in meta-analysis detected by a simple, graphical test. Brit Med J 1997; 315: 629-34.
14. Orwin R,. A fail-safe N for effect size in meta-analysis. J Educ Stat 1983; 8: 157-9.
15. Parker DR, Kingham JG,. Type I autoimmune hepatitis is primarily a disease of later life. Q J Med 1997; 90: 289-96.
16. Newton JL, Burt AD, Park JB, Matthew J, Bassendine MF, James OF,. Autoimmune hepatitis in older patients. Age Ageing 1997; 26: 441-4.
17. Schramm C, Kanzler S, Meyer zum Buschenfelde KH, Galle PR, Lohse AW,. Autoimmune hepatitis in the elderly. Am J Gastroenterol 2001; 96: 1587-91.
18. Verslype C, George C, Buchel E, Nevens F, Van Steenbergen W, Fevery J,. Diagnosis and treatment of autoimmune hepatitis at age 65 and older. Aliment Pharm Ther 2005; 21: 695-9.
19. Granito A, Muratori L, Pappas G, et al,. Clinical features of type 1 autoimmune hepatitis in elderly Italian patients. Aliment Pharm Ther 2005; 21: 1273-7.
20. Czaja AJ, Carpenter HA,. Distinctive clinical phenotype and treatment outcome of type 1 autoimmune hepatitis in the elderly. Hepatology 2006; 43: 532-8.
21. Al-Chalabi T, Boccato S, Portmann BC, McFarlane IG, Heneghan MA,. Autoimmune hepatitis (AIH) in the elderly: a systematic retrospective analysis of a large group of consecutive patients with definite AIH followed at a tertiary referral centre. J Hepatol 2006; 45: 575-83.
22. Xie B, Parekh RM, Sood S, et al,. S1262 Autoimmune hepatitis in elderly is usually an advanced disease at presentation, is less symptomatic and relapse is infrequent. Gastroenterology 2010; 138: S215-6.
23. Floreani A, Niro G, Rizzotto ER, et al,. Type I autoimmune hepatitis: clinical course and outcome in an Italian multicentre study. Aliment Pharm Ther 2006; 24: 1051-7.
24. Miyake Y, Iwasaki Y, Takaki A, Kobashi H, Sakaguchi K, Shiratori Y,. Clinical features of Japanese elderly patients with type 1 autoimmune hepatitis. Internal Med 2007; 46: 1945-9.
25. Czaja AJ,. Special clinical challenges in autoimmune hepatitis: the elderly, males, pregnancy, mild disease, fulminant onset, and nonwhite patients. Semin Liver Dis 2009; 29: 315-30.
26. Medina J, Garcia-Buey L, Moreno-Otero R,. Review article: immunopathogenetic and therapeutic aspects of autoimmune hepatitis. Aliment Pharm Ther 2003; 17: 1-16.
27. Yeoman AD, Longhi MS, Heneghan MA,. Review article: the modern management of autoimmune hepatitis. Aliment Pharm Ther 2010; 31: 771-87.
28. Kanzler S, Gerken G, Lohr H, Galle PR, Meyer zum Buschenfelde KH, Lohse AW,. Duration of immunosuppressive therapy in autoimmune hepatitis. J Hepatol 2001; 34: 354-5.
29. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB,. Significance of HLA DR4 in type 1 autoimmune hepatitis. Gastroenterology 1993; 105: 1502-7.
30. Czaja AJ, Strettell MDJ, Thomson LJ, et al,. Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis. Hepatology 1997; 25: 317-23.