Beyond the randomized clinical trial: Citrate for continuous renal replacement therapy in clinical practice

Nephron - Clinical Practice

Volumn 124, Issue 1-2, 2013, Pages 119-123

  Tovey, L ^a   Dickie, H ^a   Gangi, S ^a   Terblanche, M ^a   Mckenzie, C ^a   Beale, R ^a   Treacher, D ^a   Ostermann, M ^a  

^a GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Acute kidney injury; Anticoagulation; Citrate; Continuous renal replacement therapy

Indexed keywords

CITRIC ACID; HEPARIN; PROSTACYCLIN;

ACUTE KIDNEY FAILURE; AGED; ANTICOAGULATION; ARTICLE; CLINICAL PRACTICE; CONTINUOUS RENAL REPLACEMENT THERAPY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DEVICE COMPLICATION; PARTIAL THROMBOPLASTIN TIME; PREMATURE CIRCUIT CLOTTING; PRIORITY JOURNAL;

AGED; ANTICOAGULANTS; CHELATING AGENTS; CITRIC ACID; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; MALE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RENAL REPLACEMENT THERAPY; RETROSPECTIVE STUDIES; THROMBOSIS; TREATMENT OUTCOME;

EID: 84890543462     PISSN: None     EISSN: 16602110     Source Type: Journal    
DOI: 10.1159/000355550     Document Type: Article

References (25)

1. Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten H, Ronco C, Kellum JA. Continuous renal replacement therapy: a worldwide practice survey. The beginning and ending supportive therapy for the kidney (BEST kidney) investigators. Intensive Care Med 2007; 33: 1563-1570.
2. Oudemans-van Straaten HM, Ostermann M. Bench-To-bedside review: citrate for continuous renal replacement therapy, from science to practice. Crit Care 2012; 16: 249.
3. Hetzel GR, Schmitz M, Wissing H, Ries W, Schott G, Heering PJ, Isgro F, Kribben A, Himmele R, Grabensee B, Rump LC. Regional citrate versus systemic heparin for anticoagulation in critically ill patients on continuous venovenous haemofiltration: a prospective randomized multicentre trial. Nephrol Dial Transplant 2011; 26: 232-239.
4. Zhang Z, Hongying N. Efficacy and safety of regional citrate anticoagulation in critically ill patients undergoing continuous renal replacement therapy. Intensive Care Med 2012; 38: 20-28.
5. Wu MY, Hsu YH, Bai CH, Lin YF, Wu CH, Tam KW. Regional citrate versus heparin anticoagulation for continuous renal replacement therapy: a meta-Analysis of randomized controlled trials. Am J Kidney Dis 2012; 59: 810-818.
6. Nallamothu BK, Hayward RA, Bates ER. Beyond the randomized clinical trial: the role of effectiveness studies in evaluating cardiovascular therapies. Circulation 2008; 118: 1294-1303.
7. Ostermann M, Dickie H, Tovey L, Treacher D. Heparin algorithm for anticoagulation during continuous renal replacement therapy. Crit Care 2010; 14: 419.
8. Morgera S, Schneider M, Slowinski T, Vargas-Hein O, Zuckermann-Becker H, Peters H, Kindgen-Milles D, Neumayer HH. A safe citrate anticoagulation protocol with variable treatment efficacy and excellent control of the acid-base status. Crit Care Med 2009; 37: 2018-2024.
9. Hougaard P. Frailty models for survival data. Lifetime Data Anal 1995; 1: 255-273.
10. Oudemans-van Straaten H. Citrate anticoagulation for continuous renal replacement therapy in the critically ill. Blood Purif 2010; 29: 191-196.
11. Kutsogiannis DJ, Gibney RT, Stollery D, Gao J. Regional citrate versus systemic heparin anticoagulation for continuous renal replacement in critically ill patients. Kidney Int 2005; 67: 2361-2367.
12. Betjes MG, van Oosterom D, van Agteren M, van de Wetering J. Regional citrate versus heparin anticoagulation during venovenous hemofiltration in patients at low risk for bleeding: similar hemofilter survival but significantly less bleeding. J Nephrol 2007; 20: 602-608.
13. Morgera S, Scholle C, Voss C, Haase M, Vargas-Hein O, Krausch D, Meizer C, Rosseau S, Zuckermann-Becker H, Neumayer HH. Metabolic complications during regional citrate anticoagulation in continuous veno-venous hemodialysis: single-center experience. Nephron Clin Pract 2004; 97:c131-c136.
14. Durao MS, Monte JC, Batista MC, Oliveira M, Iizuka IJ, Santos BF, Pereira VG, Cendoroglo M, Santos OF. The use of regional citrate anticoagulation in acute kidney injury. Crit Care Med 2008; 36: 3024-3029.
15. Monchi M, Berghmans D, Ledoux D, Canivet JL, Dubois B, Damas P. Citrate versus heparin for anticoagulation in continuous venovenous hemofiltration: a prospective randomized study. Intensive Care Med 2004; 30: 260-265.
16. Clinical Practice Guidelines for Acute Kidney Injury 2012. http://www.kdigo.org/clinical-practice-guidelines/AKI.php.
17. UK Renal Association: Clinical Practice Guidelines Acute Kidney Injury. http://www. renal.org/clinical/guidelinessection/ AcuteKidneyInjury.aspx.
18. Morgera S, Schneider M, Slowinski T, Vargas-Hein O, Zuckermann-Becker H, Peters H, Kindgen-Milles D, Neumayer HH. A safe citrate anticoagulation protocol with variable treatment efficacy and excellent control of the acidbase status. Crit Care Med 2009; 37: 2018-2024.
19. Oudemans-Van Straaten HM, Bosman RJ, Koopmans M, van der Voort PH, Wester JP, van der Spoel JI, Dijksman LM, Zandstra DF. Citrate anticoagulation for continuous venovenous hemofiltration. Crit Care Med 2009; 37: 545-552.
20. Fealy N, Baldwin I, Johnstone M, Egi M, Bellomo R. A pilot randomized controlled crossover study comparing regional heparinization to regional citrate anticoagulation for continuous venovenous hemofiltration. Int J Artif Organs 2007; 30: 301-307.
21. Schultheiss C, Saugel B, Philip V, Thies P, Noe S, Mayr U, Haller B, Einwachter H, Schmid RM, Huber W. Continuous venovenous hemodialysis with regional citrate anticoagulation in patients with liver failure: a prospective observational study. Critical Care 2012; 16:R162.
22. Patel S, Wendon J. Regional citrate anticoagulation in patients with liver failure-Time for a rethink?. Crit Care 2012; 16: 153.
23. Bellomo R, Baldwin I. Anticoagulation; in Kellum J, Bellomo R, Ronco C (eds): Continuous Renal Replacement Therapy. Oxford, Oxford University Press, 2010, pp 135-140.
24. Gatward JJ, Gibbon GJ, Wrathall G, Padkin A. Renal replacement therapy for acute renal failure: a survey of practice in adult intensive care units in the United Kingdom. Anaesthesia 2008; 63: 959-966.
25. Ricci Z, Ronco C, Bachetoni A, D'Amico G, Rossi S, Alessandri E, Rocco M, Pietropaoli P. Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion. Crit Care 2006; 10:R67.