2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: A step toward new antiexcitotoxic agents

Journal of Medicinal Chemistry

Volumn 56, Issue 23, 2013, Pages 9482-9495

  Vallerini, Gian Paolo ^a   Amori, Laura ^a   Beato, Claudia ^a   Tararina, Margarita ^b   Wang, Xiao Dan ^b,c   Schwarcz, Robert ^b   Costantino, Gabriele ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

^c TIANJIN HUANHU HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 6 METHYLNICOTINIC ACID 1 OXIDE DERIVATIVE; 2 AMINONICOTINIC ACID 1 OXIDE DERIVATIVE; ANTIEXCITOTOXIC AGENT; NICOTINIC ACID DERIVATIVE; QUINOLINIC ACID; QUINOLINIC ACID INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; BRAIN TISSUE; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DOCKING; NONHUMAN; RAT; TISSUE HOMOGENATE;

EID: 84890497231     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401249c     Document Type: Article

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