The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-Chloro-3-hydroxyanthranilate

Biochemistry

Volumn 44, Issue 21, 2005, Pages 7623-7631

  Colabroy, Keri L ^a   Zhai, Huili ^a   Li, Tingfeng ^b   Ge, Ying ^a   Zhang, Yang ^a   Liu, Aimin ^b   Ealick, Steven E ^a   McLafferty, Fred W ^a   Begley, Tadhg P ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2-AMINO-3-CARBOXYMUCONIC SEMIALDEHYDE; OXIDATIVE RING-OPENING; QUINOLINATE; SUPEROXIDES;

BACTERIA; BIOSYNTHESIS; CATALYSIS; ENZYME INHIBITION; NEUROLOGY; OXIDATION; OXYGEN;

ENZYMES;

3 HYDROXYANTHRANILATE 3,4 DIOXYGENASE; 4 CHLORO 3 HYDROXYANTHRANILIC ACID; CYSTEINE; DISULFIDE; FERROUS ION; QUINOLINIC ACID; SUPEROXIDE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME STRUCTURE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE; 3-HYDROXYANTHRANILIC ACID; AMINO ACID SEQUENCE; DIOXYGENASES; DISULFIDES; DITHIONITROBENZOIC ACID; ENZYME ACTIVATION; ENZYME INHIBITORS; ESCHERICHIA COLI; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; OXYGEN CONSUMPTION; RALSTONIA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTRATE SPECIFICITY; SUPEROXIDES;

BACTERIA (MICROORGANISMS);

EID: 19644366181     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0473455     Document Type: Article

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