Does the presence of thyroid antibodies affect the course and outcome of pregnancy in type 1 diabetic women?

Journal of Perinatal Medicine

Volumn 42, Issue 1, 2014, Pages 69-74

  Sarantopoulou, Vasiliki ^a   Vasileiou, Vasiliki ^a   Sarika, Leda ^a   Philippou, George ^a   Alevizaki, Maria ^b   Antsaklis, Aris ^c   Anastasiou, Eleni ^a  

^a ALEXANDRA HOSPITAL   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c UNIVERSITY OF ATHENS   (Greece)

Author keywords

Diabetes type 1; Metabolic control; Thyroid antibodies; TSH

Indexed keywords

HEMOGLOBIN A1C; INSULIN; LEVOTHYROXINE; PROPYLTHIOURACIL; SHORT ACTING INSULIN; THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; THYROXINE;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; BODY MASS; CONTROLLED STUDY; DIABETIC RETINOPATHY; FEMALE; FIRST TRIMESTER PREGNANCY; FREE THYROXINE INDEX; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; GRAVES DISEASE; HUMAN; HYPERTHYROIDISM; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MICROALBUMINURIA; OBSERVATIONAL STUDY; PREGNANCY DIABETES MELLITUS; PREGNANCY OUTCOME; PREGNANT WOMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; SECOND TRIMESTER PREGNANCY; SPONTANEOUS ABORTION; SUBCLINICAL HYPOTHYROIDISM; THIRD TRIMESTER PREGNANCY;

ADULT; AUTOANTIBODIES; AUTOANTIGENS; BIOLOGICAL MARKERS; DIABETES MELLITUS, TYPE 1; FEMALE; FOLLOW-UP STUDIES; HUMANS; IODIDE PEROXIDASE; IRON-BINDING PROTEINS; PREGNANCY; PREGNANCY IN DIABETICS; PREGNANCY OUTCOME; PROSPECTIVE STUDIES;

EID: 84890494709     PISSN: 03005577     EISSN: 16193997     Source Type: Journal    
DOI: 10.1515/jpm-2012-0273     Document Type: Article

References (19)

1. Alvarez-Marfany M, Roman SH, Drexler AJ, Robertson C, Stagnaro-Green A. Long-term prospective study of postpartum thyroid dysfunction in women with insulin dependent diabetes mellitus. J Clin Endocrinol Metab. 1994;79:10-6.
2. Bech K, Høier-Madsen M, Feldt-Rasmussen U, Jensen BM, Mølsted-Pedersen L, Kühl C. Thyroid function and autoimmune manifestations in insulin-dependent diabetes mellitus during and after pregnancy. Acta Endocrinol (Copenh). 1991;124: 534-9.
3. Challis JR, Lockwood CJ, Myatt L, Norman JE, Strauss JF III, Petraglia F. Inflammation and pregnancy. Reprod Sci. 2009;16:206-15.
4. De Groot L, Abalovich M, Alexander EK, Amino N, Barbour L, Cobin RH, et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012;97:2543-65.
5. Dupont WD, Plummer WD. Power and sample size calculations: a review and computer program. Control Clin Trials. 1990;11: 116-28.
6. Fernandez-Soto L, Gonzalez A, Lobón JA, Lopez JA, Peterson CM, Escobar-Jiménez F. Thyroid peroxidase autoantibodies predict poor metabolic control and need for thyroid treatment in pregnant IDDM women. Diabetes Care. 1997;20:1524-8.
7. Gallas PR, Stolk RP, Bakker K, Endert E, Wiersinga WM. Thyroid dysfunction during pregnancy and in the first postpartum year in women with diabetes mellitus type 1. Eur J Endocrinol. 2002;147:443-51.
8. Glinoer D. Miscarriage in women with positive anti-TPO antibodies: is thyroxine the answer? J Clin Endocrinol Metab. 2006;91:2500-2.
9. Glinoer D, Riahi M, Grün JP, Kinthaert J. Risk of subclinical hypothyroidism in pregnant women with asymptomatic autoimmune thyroid disorders. J Clin Endocrinol Metab. 1994;79:197-204.
10. Jaeger C, Hatziagelaki E, Petzoldt R, Bretzel RG, Reinhard G. Comparative analysis of organ-specific autoantibodies and celiac disease-associated antibodies in type 1 diabetic patients, their first-degree relatives, and healthy control subjects, Diabetes Care. 2001;24:27-32.
11. Li Y, Shan Z, Teng W, Yu X, Li Y, Fan C, et al. Abnormalities of maternal thyroid function during pregnancy affect neuropsychological development of their children at 25-30 months. Clin Endocrinol (Oxf). 2010;72:825-9.
12. Männistö T, Vääräsmäki M, Pouta A, Hartikainen AL, Ruokonen A, Surcel HM, et al. Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study. J Clin Endocrinol Metab. 2009;94:772-29.
13. Negro R, Formoso G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H. Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. J Clin Endocrinol Metab. 2006;91:2587-91.
14. Perros P, McCrimmon RJ, Shaw G, Frier BM. Frequency of thyroid dysfunction in diabetic patients: value of annual screening. Diabet Med. 1995;12:622-7.
15. Poppe K, Glinoer D. Thyroid autoimmunity and hypothyroidism before and during pregnancy. Hum Reprod Update. 2003;9:149-61.
16. Roldán MB, Alonso M, Barrio R. Thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus. Diabetes Nutr Metab. 1999;12:27-31.
17. Stagnaro-Green A, Abalovich M, Alexander E, Azizi F, Mestman J, Negro R, et al. American Thyroid Association Taskforce on Thyroid Disease During Pregnancy and Postpartum. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid. 2011;21:1081-125.
18. Thangaratinam S, Tan A, Knox E, Kilby MD, Franklyn J, Coomarasamy A. Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence. Br Med J. 2011;342:d2616.
19. Vestgaard M, Nielsen LR, Rasmussen AK, Damm P, Mathiesen ER. Thyroid peroxidase antibodies in pregnant women with type 1 diabetes: impact on thyroid function, metabolic control and pregnancy outcome. Acta Obstet Gynecol Scand. 2008;87:1336-42.