Synergy of ferrous ion on 5-aminolevulinic acid-mediated growth inhibition of Plasmodium falciparum

Journal of Biochemistry

Volumn 154, Issue 6, 2013, Pages 501-504

  Komatsuya, Keisuke ^a   Hata, Masayuki ^a   Balogun, Emmanuel O ^a,b,c   Hikosaka, Kenji ^a   Suzuki, Shigeo ^a,d   Takahashi, Kiwamu ^d   Tanaka, Tohru ^d   Nakajima, Motowo ^d   Ogura, Shun Ichiro ^e   Sato, Shigeharu ^f   Kita, Kiyoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^c AHMADU BELLO UNIVERSITY   (Nigeria)

^d SBI Pharmaceuticals Co   (Japan)

^e TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^f NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

5 aminolevulinic acid (ALA); Haem synthesis; Malaria; Plasmodium falciparum

Indexed keywords

ACYL CARRIER PROTEIN; AMINOLEVULINIC ACID; COPROPORPHYRIN; COPROPORPHYRIN 3; FERROUS ION; HEME; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; APICOPLAST; ARTICLE; BIOSYNTHESIS; DRUG EFFECT; DRUG POTENTIATION; FENTON REACTION; GROWTH INHIBITION; NONHUMAN; PLASMODIUM FALCIPARUM; SCHIZONT; TROPHOZOITE;

5-AMINOLEVULINIC ACID (ALA); HAEM SYNTHESIS; MALARIA; PLASMODIUM FALCIPARUM;

AMINOLEVULINIC ACID; ANTIMALARIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FERROUS COMPOUNDS; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84890491304     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvt096     Document Type: Article

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