OPN gene polymorphism and the serum opn levels confer the susceptibility and prognosis of ischemic stroke in Chinese patients

Cellular Physiology and Biochemistry

Volumn 32, Issue 6, 2013, Pages 1798-1807

  Jing, Meng ^a   Li, Baoxin ^a   Hou, Xuwei ^b   Shoba, Jayaram ^c   Li, Changyu ^a   Liang, Hongsheng ^a   Zhang, Xiangtong ^a   Liu, Enzhong ^a   Yang, Baofeng ^a   Meng, Xiangxi ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c Nanjing Medical University ^*  (India)

Author keywords

Chinese; Ischemic stroke; Osteopontin; Prognosis; Susceptibility

Indexed keywords

C REACTIVE PROTEIN; CREATININE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OSTEOPONTIN; THROMBIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; BARTHEL INDEX; BRAIN ISCHEMIA; CAROTID ARTERY BIFURCATION; CHINESE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; DNA POLYMORPHISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PATIENT RISK; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; RANKIN SCALE; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; STROKE PATIENT;

ADULT; ALLELES; AREA UNDER CURVE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DISEASE SUSCEPTIBILITY; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; ODDS RATIO; OSTEOPONTIN; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; ROC CURVE; SEVERITY OF ILLNESS INDEX; STROKE; THROMBIN;

EID: 84890488362     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000356613     Document Type: Article

References (41)

1. Cerniauskaite M, Quintas R, Koutsogeorgou E, Meucci P, Sattin D, Leonardi M, Raggi A: Quality-of-life and disability in patients with stroke. Am J Phys Med Rehabil 2012;91:S39-47.
2. Mittmann N, Seung SJ, Hill MD, Phillips SJ, Hachinski V, Cote R, Buck BH, Mackey A, Gladstone DJ, Howse DC, Shuaib A, Sharma M: Impact of disability status on ischemic stroke costs in Canada in the first year. Can J Neurol Sci 2012;39:793-800.
3. Goljar N, Burger H, Vidmar G, Leonardi M, Marincek C: Measuring patterns of disability using the International Classification of Functioning, Disability and Health in the post -Acute stroke rehabilitation setting. J Rehabil Med 2011;43:590-601.
4. Wang Y, Hou X, Li Y: Association between transforming growth factor beta1 polymorphisms and atrial fibrillation in essential hypertensive subjects. J Biomed Sci 2010;17:23.
5. Zhang N, Yu JT, Yu NN, Lu RC, Ma T, Wang ND, Miao D, Song JH, Tan L: Interleukin-18 promoter polymorphisms and risk of ischemic stroke. Brain Res Bull 2010;81:590-594.
6. Lopaciuk S, Windyga J, Watala CW, Bykowska K, Pietrucha T, Kwiecinski H, Czlonkowska A, Kuczynska-Zardzewialy A, Jackson AA, Carew JA, Bauer KA: Polymorphisms in the factor VII gene and ischemic stroke in young adults. Blood Coagul Fibrinolysis 2010;21:442-447.
7. Tuttolomondo A, Di Raimondo D, Forte GI, Casuccio A, Vaccarino L, Scola L, Pecoraro R, Serio A, Clemente G, Arnao V, Palmeri M, Misiano G, Lio D, Pinto A, Licata G: Single nucleotide polymorphisms (SNPs) of proinflammatory/ anti-inflammatory and thrombotic/fibrinolytic genes in patients with acute ischemic stroke in relation to TOAST subtype. Cytokine 2012;58:398-405.
8. Ben-Assayag E, Shenhar-Tsarfaty S, Bova I, Berliner S, Shopin L, Peretz H, Usher S, Shapira I, Bornstein NM: Triggered C-reactive protein (CRP) concentrations and the CRP gene-717A>G polymorphism in acute stroke or transient ischemic attack. Eur J Neurol 2007;14:315-320.
9. Greisenegger S, Zehetmayer S, Bauer P, Endler G, Ferrari J, Lang W, Janisiw M, Steiner L, Cheng S, Lalouschek W, Mannhalter C: Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay. Clin Chem 2009;55:134-138.
10. Hou XW, Yang RQ, Zhong YG, Gao W, Sun SP, Wang NF: G501C polymorphism of the oxidized LDL receptor gene is associated with albuminuria in Chinese essential hypertension patients. Genet Mol Res 2011;10.
11. Giachelli CM, Steitz S: Osteopontin: A versatile regulator of inflammation and biomineralization. Matrix Biol 2000;19:615-622.
12. Heilmann K, Hoffmann U, Witte E, Loddenkemper C, Sina C, Schreiber S, Hayford C, Holzlohner P, Wolk K, Tchatchou E, Moos V, Zeitz M, Sabat R, Gunthert U, Wittig BM: Osteopontin as two-sided mediator of intestinal inflammation. J Cell Mol Med 2009;13:1162-1174.
13. Wolak T, Kim H, Ren Y, Kim J, Vaziri ND, Nicholas SB: Osteopontin modulates angiotensin II-induced inflammation, oxidative stress, and fibrosis of the kidney. Kidney Int 2009;76:32-43.
14. Zhivkova-Galunska M, Adwan H, Eyol E, Kleeff J, Kolb A, Bergmann F, Berger MR: Osteopontin but not osteonectin favors the metastatic growth of pancreatic cancer cell lines. Cancer Biol Ther 2010;10:54-64.
15. Yan YP, Lang BT, Vemuganti R, Dempsey RJ: Osteopontin is a mediator of the lateral migration of neuroblasts from the subventricular zone after focal cerebral ischemia. Neurochem Int 2009;55:826-832.
16. Kurata M, Okura T, Kumon Y, Tagawa M, Watanabe H, Nakahara T, Miyazaki T, Higaki J, Nose M: Plasma thrombin-cleaved osteopontin elevation after carotid artery stenting in symptomatic ischemic stroke patients. Hypertens Res 2012;35:207-212.
17. Mendioroz M, Fernandez-Cadenas I, Rosell A, Delgado P, Domingues-Montanari S, Ribo M, Penalba A, Quintana M, Alvarez-Sabin J, Montaner J: Osteopontin predicts long-term functional outcome among ischemic stroke patients. J Neurol 2011;258:486-493.
18. Chiu YW, Tu HF, Wang IK, Wu CH, Chang KW, Liu TY, Kao SY: The implication of osteopontin (OPN) expression and genetic polymorphisms of OPN promoter in oral carcinogenesis. Oral Oncol 2010;46:302-306.
19. Trivedi T, Franek BS, Green SL, Kariuki SN, Kumabe M, Mikolaitis RA, Jolly M, Utset TO, Niewold TB: Osteopontin alleles are associated with clinical characteristics in systemic lupus erythematosus. J Biomed Biotechnol 2011;2011:802581.
20. Mochida S, Hashimoto M, Matsui A, Naito M, Inao M, Nagoshi S, Nagano M, Egashira T, Mishiro S, Fujiwara K: Genetic polymorphims in promoter region of osteopontin gene may be a marker reflecting hepatitis activity in chronic hepatitis C patients. Biochem Biophys Res Commun 2004;313:1079-1085.
21. Miyazaki T, Ono M, Qu WM, Zhang MC, Mori S, Nakatsuru S, Nakamura Y, Sawasaki T, Endo Y, Nose M: Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice. Eur J Immunol 2005;35:1510-1520.
22. Kim Y, Lee C: Haplotype analysis revealed a genetic influence of osteopontin on large artery atherosclerosis. J Biomed Sci 2008;15:529-533.
23. Farooq MU, Chaudhry AH, Amin K, Majid A: The WHO STEPwise Approach to Stroke Surveillance. J Coll Physicians Surg Pak 2008;18:665.
24. Fure B, Wyller TB, Thommessen B: TOAST criteria applied in acute ischemic stroke. Acta Neurol Scand 2005;112:254-258.
25. Kasner SE, Chalela JA, Luciano JM, Cucchiara BL, Raps EC, McGarvey ML, Conroy MB, Localio AR: Reliability and validity of estimating the NIH stroke scale score from medical records. Stroke 1999;30:1534-1537.
26. Mahoney FI, Barthel DW: Functional Evaluation: The Barthel Index. Md State Med J 1965;14:61-65.
27. Coletta EM, Murphy JB: Physical and functional assessment of the elderly stroke patient. Am Fam Physician 1994;49:1777-1785.
28. Hasegawa M, Nakoshi Y, Iino T, Sudo A, Segawa T, Maeda M, Yoshida T, Uchida A: Thrombin-cleaved osteopontin in synovial fluid of subjects with rheumatoid arthritis. J Rheumatol 2009;36:240-245.
29. Jono S: [Osteopontin and atherosclerosis]. Nihon Rinsho 2005;63:635-640.
30. Kurata M, Okura T, Watanabe S, Fukuoka T, Higaki J: Osteopontin and carotid atherosclerosis in patients with essential hypertension. Clin Sci (Lond) 2006;111:319-324.
31. Hou X, Appleby N, Fuentes T, Longo LD, Bailey LL, Hasaniya N, Kearns-Jonker M: Isolation, Characterization, and Spatial Distribution of Cardiac Progenitor Cells in the Sheep Heart. J Clin Exp Cardiolog 2012;S6.
32. Hou XW, Son J, Wang Y, Ru YX, Lian Q, Majiti W, Amazouzi A, Zhou YL, Wang PX, Han ZC: Granulocyte colonystimulating factor reduces cardiomyocyte apoptosis and improves cardiac function in adriamycin-induced cardiomyopathy in rats. Cardiovasc Drugs Ther 2006;20:85-91.
33. Xu H, Hou X, Wang N, Hui B, Jin J, Yun S, Wang X, He X, He J, Zhang S, Han Y: Gender-specific effect of estrogen receptor-1 gene polymorphisms in coronary artery disease and its angiographic severity in Chinese population. Clin Chim Acta 2008;395:130-133.
34. O'Brien ER, Garvin MR, Stewart DK, Hinohara T, Simpson JB, Schwartz SM, Giachelli CM: Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arterioscler Thromb 1994;14:1648-1656.
35. Matsui Y, Rittling SR, Okamoto H, Inobe M, Jia N, Shimizu T, Akino M, Sugawara T, Morimoto J, Kimura C, Kon S, Denhardt D, Kitabatake A, Uede T: Osteopontin deficiency attenuates atherosclerosis in female apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2003;23:1029-1034.
36. Golledge J, McCann M, Mangan S, Lam A, Karan M: Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosis. Stroke 2004;35:1636-1641.
37. Wang X, Louden C, Yue TL, Ellison JA, Barone FC, Solleveld HA, Feuerstein GZ: Delayed expression of osteopontin after focal stroke in the rat. J Neurosci 1998;18:2075-2083.
38. Giacopelli F, Marciano R, Pistorio A, Catarsi P, Canini S, Karsenty G, Ravazzolo R: Polymorphisms in the osteopontin promoter affect its transcriptional activity. Physiol Genomics 2004;20:87-96.
39. Schultz J, Lorenz P, Ibrahim SM, Kundt G, Gross G, Kunz M: The functional-443T/C osteopontin promoter polymorphism influences osteopontin gene expression in melanoma cells via binding of c-Myb transcription factor. Mol Carcinog 2009;48:14-23.
40. de las Fuentes L, Gu CC, Mathews SJ, Reagan JL, Ruthmann NP, Waggoner AD, Lai CF, Towler DA, Davila-Roman VG: Osteopontin promoter polymorphism is associated with increased carotid intima-media thickness. J Am Soc Echocardiogr 2008;21:954-960.
41. Brenner D, Labreuche J, Touboul PJ, Schmidt-Petersen K, Poirier O, Perret C, Schonfelder J, Combadiere C, Lathrop M, Cambien F, Brand-Herrmann SM, Amarenco P: Cytokine polymorphisms associated with carotid intima-media thickness in stroke patients. Stroke 2006;37:1691-1696.