Review of the state of renal nerve ablation for patients with severe and resistant hypertension

Journal of the American Society of Hypertension

Volumn 7, Issue 6, 2013, Pages 484-493

  Gulati, Vinay ^a   White, William B ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

renal nerve ablation; Resistant hypertension; sympathetic nervous system

Indexed keywords

ABLATION THERAPY; ADRENERGIC SYSTEM; BLOOD PRESSURE REGULATION; DEVICE SAFETY; DISEASE SEVERITY; GLOMERULUS FILTRATION RATE; HEART ARRHYTHMIA; HEART FAILURE; HUMAN; INNERVATION; KIDNEY DENERVATION; KIDNEY NERVE; KIDNEY TUBULE ABSORPTION; LUMBAR SYMPATHECTOMY; METABOLIC DISORDER; PRIORITY JOURNAL; RADIOFREQUENCY ABLATION; RADIOFREQUENCY ABLATION DEVICE; RENIN RELEASE; RESISTANT HYPERTENSION; REVIEW; RISK ASSESSMENT; SLEEP DISORDERED BREATHING;

RENAL NERVE ABLATION; RESISTANT HYPERTENSION; SYMPATHETIC NERVOUS SYSTEM;

BLOOD PRESSURE; CATHETER ABLATION; DRUG RESISTANCE; HUMANS; HYPERTENSION, RENAL; KIDNEY; SYMPATHECTOMY;

EID: 84890440007     PISSN: 19331711     EISSN: 18787436     Source Type: Journal    
DOI: 10.1016/j.jash.2013.07.003     Document Type: Review

References (62)

1. World Health Organization World Health Report 2002: Reducing risks, promoting healthy life 2002 World Health Organization Geneva, Switzerland
2. K. Wolf-Maier, R.S. Cooper, H. Kramer, J.R. Banegas, S. Giampaoli, and M.R. Joffres Hypertension treatment and control in five European countries, Canada, and the United States Hypertension 43 2004 10 17
3. D.A. Calhoun, D. Jones, S. Textor, D.C. Goff, T.P. Murphy, and R.D. Toto Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research Circulation 117 2008 e510 e526
4. B.M. Egan, Y. Zhao, R.N. Axon, W.A. Brzezinski, and K.C. Ferdinand Uncontrolled and apparent treatment resistant hypertension in the United States, 1988-2008 Circulation 124 2011 1046 1058
5. S.D. Persell Prevalence of resistant hypertension in the United States, 2003-2008 Hypertension 57 2011 1076 1080
6. K.A. Evelyn, F. Alexander, and S.R. Cooper Effect of sympathectomy on blood pressure in hypertension: a review of 13 years' experience of the Massachusetts General Hospital JAMA 140 1949 592 602
7. R.H. Smithwick, R.D. Bush, D. Kinsey, and G.P. Whitelaw Hypertension and associated cardiovascular disease; comparison of male and female mortality rates and their influence on selection of therapy JAMA 160 1956 1023 1026
8. K.S. Grimson Total thoracic and partial to total lumbar sympathectomy and celiac ganglionectomy in the treatment of hypertension Ann Surg 114 1941 753 775
9. R.H. Smithwick Surgery in hypertension Lancet 2 1948 65
10. K.S. Grimson, E.S. Orgain, B. Anderson, R.A. Broome, and F.H. Longino Results of treatment of patients with hypertension by total thoracic and partial to total lumbar sympathectomy, splanchnicectomy and celiac ganglionectomy Ann Surg 129 1949 850 871
11. G.F. DiBona, and U.C. Kopp Neural control of renal function Physiol Rev 77 1997 75 197
12. H. Krum, P. Sobotka, F. Mahfoud, M. Böhm, M. Esler, and M. Schlaich Device-based antihypertensive therapy: therapeutic modulation of the autonomic nervous system Circulation 123 2011 209 215
13. L. Barajas, L. Liu, and K. Powers Anatomy of the renal innervation: intrarenal aspects and ganglia of origin Can J Physiol Pharmacol 70 1992 735 749
14. M. Esler, G. Jennings, P. Korner, I. Willett, F. Dudley, and G. Hasking The assessment of human sympathetic nervous system activity from measurements of norepinephrine turnover Hypertension 11 1988 3 20
15. M. Esler The sympathetic system and hypertension Am J Hypertens 13 6 Pt 2 2000 99S 105S
16. A. Stella, and A. Zanchetti Functional role of renal afferents Physiol Rev 71 1991 659 682
17. J. Ciriello, and C.V. de Oliveira Renal afferents and hypertension Curr Hypertens Rep 4 2002 136 142
18. U.C. Kopp, L.A. Smith, and G.F. DiBona Renorenal reflexes: neural components of ipsilateral and contralateral renal responses Am J Physiol 249 1985 F507 F517
19. R.L. Converse Jr., T.N. Jacobsen, R.D. Toto, C.M. Jost, F. Cosentino, and F. Fouad-Tarazi Sympathetic overactivity in patients with chronic renal failure N Engl J Med 327 1992 1912 1918
20. M. Hausberg, M. Kosch, P. Harmelink, M. Barenbrock, H. Hohage, and K. Kisters Sympathetic nerve activity in end-stage renal disease Circulation 106 2002 1974 1979
21. F.T. Huysmans, F.H. van Heusden, J.F. Wetzels, A.J. Hoitsma, and R.A. Koene Antihypertensive effect of beta blockade in renal transplant recipients with or without host kidneys Transplantation 46 1988 234 237
22. G. Ligtenberg, P.J. Blankestijn, P.L. Oey, I.H. Klein, L.T. Dijkhorst-Oei, and F. Boomsma Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure N Engl J Med 340 1999 1321 1328
23. H. Krum, M. Schlaich, R. Whitbourn, P.A. Sobotka, J. Sadowski, and K. Bartus Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study Lancet 373 2009 1275 1281
24. F. Mahfoud, T.F. Lüscher, B. Andersson, I. Baumgartner, R. Cifkova, and C. Dimario Expert consensus document from the European Society of Cardiology on catheter-based renal denervation Eur Heart J 34 2013 2149 2157
25. D. Prochnau, N. Lucas, H. Kuehnert, H.R. Figulla, and R. Surber Catheter- based renal denervation for drug-resistant hypertension by using a standard electrophysiology catheter EuroIntervention 7 2012 1077 1080
26. The Symplicity HTN-1 Investigators: Three-year follow-up of Symplicity HTN-1 trial. Abstract presented at the 61st Annual Scientific Sessions of the American College of Cardiology. Chicago, IL; March 25, 2012.
27. Symplicity HTN-2 Investigators Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial Lancet 376 2010 1903 1909
28. O'Riordan M: BP reductions with renal denervation durable to 30 months: Symplicity HTN-2. Theheart.org. [Clinical Conditions > Interventional/Surgery > Interventional/Surgery]. May 17, 2013. Available at: http://www.theheart. org/article/1541263.do. Accessed on May 28, 2013.
29. D.E. Kandzari, D.L. Bhatt, P.A. Sobotka, W.W. O'Neill, M. Esler, and J.M. Flack Catheter-based renal denervation for resistant hypertension: rationale and design of the Symplicity HTN-3 Trial Clin Cardiol 35 2012 528 535
30. Worthley S. Safety and efficacy of a novel quadrapolar renal denervation catheter in patients with resistant hypertension: a first-in-man multicenter study. Abstract presented at the 2012 Annual Scientific Sessions of the European Association for Percutaneous Cardiovascular Interventions. Paris, France; May 16, 2012.
31. Hoppe U: Clinical experience with Vessix Vascular balloon renal denervation catheter. Abstract presented at the 2012 Annual Scientific Sessions of the European Association for Percutaneous Cardiovascular Interventions. Paris, France; May 17, 2012.
32. J.A. Ormiston, T. Watson, N. van Pelt, R. Stewart, J.T. Stewart, and J.M. White Renal denervation for resistant hypertension using an irrigated radiofrequency balloon: 12-month results from the Renal Hypertension Ablation System (RHAS) trial EuroIntervention 9 2013 70 74
33. Bonan, R: PARADISE: first-in-man results of a novel circumferential catheter-based ultrasound technology for renal denervation. Abstract presented at the 2012 Annual Scientific Sessions of the European Association for Percutaneous Cardiovascular Interventions. Paris, France; May 16, 2012.
34. P.T. Manning, C.W. Powers, R.E. Schmidt, and E.M. Johnson Jr. Guanethidine-induced destruction of peripheral sympathetic neurons occurs by an immune-mediated mechanism J Neurosci 3 1983 714 724
35. F. Mahfoud, B. Cremers, J. Janker, B. Link, O. Vonend, and C. Ukena Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension Hypertension 60 2012 419 424
36. D. Hering, F. Mahfoud, A.S. Walton, H. Krum, G.W. Lambert, and E.A. Lambert Renal denervation in moderate to severe CKD J Am Soc Nephrol 23 2012 1250 1257
37. Wood S. EnligHTN-1: BP drops durable, safe at one year, as renal-denervation mania grows. Theheart.org. [Clinical Conditions > Hypertension > Hypertension]; May 24, 2013. Available at: http://www.theheart.org/article/1543267.do. Accessed on May 28, 2013.
38. G. Parati, and M. Esler The human sympathetic nervous system: its relevance in hypertension and heart failure Eur Heart J 33 2012 1058 1066
39. M. Petersson, P. Friberg, G. Eisenhofer, G. Lambert, and B. Rundqvist Long-term outcome in relation to renal sympathetic activity in patients with chronic heart failure Eur Heart J 26 2005 906 913
40. G.F. DiBona, and L.L. Sawin Role of renal nerves in sodium retention of cirrhosis and congestive heart failure Am J Physiol 260 2 Pt 2 1991 R298 R305
41. A. Pettersson, J. Hedner, and T. Hedner Renal interaction between sympathetic activity and ANP in rats with chronic ischaemic heart failure Acta Physiol Scand 135 1989 487 492
42. T. Nozawa, A. Igawa, N. Fujii, B. Kato, N. Yoshida, and H. Asanoi Effects of long-term renal sympathetic denervation on heart failure after myocardial infarction in rats Heart Vessels 16 2002 51 56
43. J.E. Davies, C.H. Manisty, R. Petraco, A.J. Barron, B. Unsworth, and J. Mayet First-in-man safety evaluation of renal denervation for chronic systolic heart failure: Primary outcome from REACH- Pilot study Int J Cardiol 162 2013 189 192
44. P.A. Sobotka, H. Krum, M. Böhm, D.P. Francis, and M.P. Schlaich The role of renal denervation in the treatment of heart failure Curr Cardiol Rep 14 2012 285 292
45. M.C. Brandt, F. Mahfoud, S. Reda, S.H. Schirmer, E. Erdmann, and M. Böhm Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension J Am Coll Cardiol 59 2012 901 909
46. M.C. Brandt, S. Reda, F. Mahfoud, M. Lenski, M. Böhm, and U.C. Hoppe Effects of renal sympathetic denervation on arterial stiffness and central hemodynamics in patients with resistant hypertension J Am Coll Cardiol 60 2012 1956 1965
47. M.T. La Rovere, J.T. Bigger Jr., F.I. Marcus, A. Mortara, and P.J. Schwartz Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators Lancet 351 1998 478 484
48. F. Himmel, J. Weil, M. Reppel, K. Mortensen, K. Franzen, and L. Ansgar Improved heart rate dynamics in patients undergoing percutaneous renal denervation J Clin Hypertens (Greenwich) 14 2012 654 655
49. C. Ukena, F. Mahfoud, I. Kindermann, C. Barth, M. Lenski, and M. Kindermann Cardiorespiratory response to exercise after renal sympathetic denervation in patients with resistant hypertension J Am Coll Cardiol 58 2011 1176 1182
50. F. Mahfoud, M. Lenski, C. Ukena, C. Barth, A. Razouk, and D. Fischer Influence of renal sympathetic denervation on orthostatic function in patients with resistant hypertension Circulation 126 2012 A17201
51. Ukena C, Mahfoud F, Spies A, Kindermann I, Linz D, Cremers B, et al. Effects of renal sympathetic denervation on heart rate and atrioventricular conduction in patients with resistant hypertension. Int J Cardiol. http://dx.doi.org/10.1016/j.ijcard.2012.07.027.
52. F. Mahfoud, U. Schotten, C. Ukena, H.R. Neuberger, K. Wirth, and M. Böhm Renal sympathetic denervation suppresses postapneic blood pressure rises and atrial fibrillation in a model for sleep apnea Hypertension 60 2012 172 178
53. E. Pokushalov, A. Romanov, G. Corbucci, S. Artyomenko, V. Baranova, and A. Turov A randomized comparison of pulmonary vein isolation with versus without concomitant renal artery denervation in patients with refractory symptomatic atrial fibrillation and resistant hypertension J Am Coll Cardiol 60 2012 1163 1170
54. C. Ukena, A. Bauer, F. Mahfoud, J. Schreieck, H.R. Neuberger, and C. Eick Renal sympathetic denervation for treatment of electrical storm: first-in-man experience Clin Res Cardiol 101 2012 63 67
55. Tsioufis KP, Papademetriou V, Tsiachris D, Dimitriadis K, Thomopoulos C, Kefalaet A, et al. Renal sympathetic denervation significantly reduces mean heart rate and exerts a favorable effect on atrial and ventricular arrhythmias in resistant hypertensives. Abstract presented at the American College of Cardiology 2013 Scientific Sessions. San Francisco, CA; March 9, 2013.
56. G. Grassi, R. Dell'Oro, F. Quarti-Trevano, F. Scopelliti, G. Seravalle, and F. Paleari Neuroadrenergic and reflex abnormalities in patients with metabolic syndrome Diabetologia 48 2005 1359 1365
57. F. Mahfoud, M. Schlaich, I. Kindermann, C. Ukena, B. Cremers, and M.C. Brandt Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study Circulation 123 2011 1940 1946
58. S. Julius, T. Gudbrandsson, K. Jamerson, S. Tariq Shahab, and O. Andersson The hemodynamic link between insulin resistance and hypertension J Hypertens 9 1991 983 986
59. A. Witkowski, A. Prejbisz, E. Florczak, J. Ka̧dziela, P. Śliwiński, and P. Bieleń Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and glycemic control in patients with resistant hypertension and sleep apnea Hypertension 58 2011 559 565
60. M.P. Schlaich, N. Straznicky, M. Grima, C. Ika-Sari, T. Dawood, and F. Mahfoud Renal denervation: a potential new treatment modality for polycystic ovary syndrome? J Hypertens 29 2011 991 996
61. O'Riordan M. Disappointing real-world results with renal denervation: BP reductions small with ABPM. Theheart.org. [Clinical Conditions > Hypertension > Hypertension]; Jun 17, 2013. Available at: http://www.theheart.org/ article/1552223.do. Accessed on Jul 2, 2013.
62. F. Mahfoud, C. Ukena, R.E. Schmieder, B. Cremers, L.C. Rump, and O. Vonend Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension Circulation 128 2 2013 132 140