Decreased susceptibility to tigecycline in acinetobacter baumannii mediated by a mutation in trm encoding SAM-dependent methyltransferase

Journal of Antimicrobial Chemotherapy

Volumn 69, Issue 1, 2014, Pages 72-76

  Chen, Qiong ^a   Li, Xi ^a   Zhou, Hua ^a   Jiang, Yan ^a   Chen, Yan ^a   Hua, Xiaoting ^a   Yu, Yunsong ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Efflux pumps; Serial passage experiments; Whole genome comparisons

Indexed keywords

ADENOSYL METHIONINE DEPENDENT METHYLTRANSFERASE; AZTREONAM; CEFOTAXIME; CEFTAZIDIME; CHLORAMPHENICOL; CIPROFLOXACIN; DOXYCYCLINE; GENTAMICIN; IMIPENEM; METHYLTRANSFERASE; MINOCYCLINE; NORFLOXACIN; TETRACYCLINE; TIGECYCLINE; UNCLASSIFIED DRUG;

ACINETOBACTER; ACINETOBACTER BAUMANNII; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENOME; BACTERIUM CULTURE; BACTERIUM ISOLATE; GENE MUTATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; WILD TYPE;

EFFLUX PUMPS; SERIAL PASSAGE EXPERIMENTS; WHOLE GENOME COMPARISONS;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, BACTERIAL; GENE DELETION; GENETIC COMPLEMENTATION TEST; METHYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; MINOCYCLINE; PLASMIDS; SELECTION, GENETIC; SERIAL PASSAGE;

EID: 84890407663     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt319     Document Type: Article

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