Dietary fructose intolerance, fructan intolerance and FODMAPs

Current Gastroenterology Reports

Volumn 16, Issue 1, 2014, Pages

  Fedewa, Amy ^a   Rao, Satish S C ^a,b  

^a AUGUSTA UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Breath testing; Diet; FODMAPS; Fructan intolerance; Fructose intolerance; Fructose malabsorption; Irritable bowel syndrome

Indexed keywords

CARBOHYDRATE; DISACCHARIDE; FRUCTAN; LACTASE; MONOSACCHARIDE; OLIGOSACCHARIDE; POLYOL;

ABDOMINAL DISTENSION; ABDOMINAL PAIN; ARTICLE; BLOATING; BREATH ANALYSIS; CARBOHYDRATE INTOLERANCE; DIARRHEA; ERUCTATION; GASTROINTESTINAL SYMPTOM; HEREDITARY FRUCTOSE INTOLERANCE; IRRITABLE COLON; LONG TERM CARE; QUALITY OF LIFE; DIET THERAPY; FOOD ALLERGY; HUMAN; LOW CARBOHYDRATE DIET; METHODOLOGY; REVIEW;

BREATH TESTS; DIET, CARBOHYDRATE-RESTRICTED; FOOD HYPERSENSITIVITY; FRUCTANS; FRUCTOSE INTOLERANCE; HUMANS; IRRITABLE BOWEL SYNDROME;

EID: 84890402192     PISSN: 15228037     EISSN: 1534312X     Source Type: Journal    
DOI: 10.1007/s11894-013-0370-0     Document Type: Article

References (39)

1. Hungin AP, Chang L, Locke GR, Dennis EH, Barghout V.Irritable bowel syndrome in the United States: prevalence, symptom patterns and impact. Aliment Pharmacol Ther. 2005;21:1365-75. (Pubitemid 40813683)
2. Chang L. Review article: epidemiology and quality of life in functional gastrointestinal disorders. Aliment Pharmacol Ther. 2004;20 Suppl 7:31-9. (Pubitemid 39657674)
3. Böhn L, Störsrud S, Törnblom H, Bengtsson U, Simrén M. Selfreported food-related gastrointestinal symptoms of IBS are common and associated with more severe symptoms and reduced quality of life. Am J Gastroenterol. 2013;108:634-41.
4. HeizerWD, Southern S,McGovern S. The role of diet in symptomsof irritable bowel syndrome in adults: a narrative review. J Am Diet Assoc. 2009;109:1204-14.
5. Bray GA, Nielsen SJ, Popkin BM. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am Clin Nutr. 2004;79:537-43. (Pubitemid 41103894)
6. Economic Research Service, USDA. Table 49-US total estimated deliveries of caloric sweeteners for domestic food and beverage use, by calendar year. 2003.
7. Choi YK, Johlin Jr FC, Summers RW, JacksonM, Rao SS. Fructose intolerance: an under-recognized problem. Am J Gastroenterol. 2003;98:1348-53. (Pubitemid 36741533)
8. Choi YK, Kraft N, Zimmerman B, Jackson M, Rao SS. Fructose intolerance in IBS and utility of fructose-restricted diet. J Clin Gastroenterol. 2008;42:233-8. (Pubitemid 351301486)
9. Wilder-Smith CH, Li X, Ho SSY, Leong SM, Wong RK, Koay ESC, et al. Fructose transporters GLUT5 and GLUT2 expression in adult patients with fructose intolerance. United Eur Gastroenterol J. 2013. doi:10.1177/2050640613505279
10. Riby JE, Fujisawa T, Kretchmer N. Fructose absorption. Am J Clin Nutr. 1993;58:748S-53S. (Pubitemid 23319972)
11. Putkonen L, Yao CK, Gibson PR. Fructose malabsorption syndrome. Curr Opin Clin Nutr Metab Care. 2013;16:473-7.
12. DeBosch BJ, Chi M, Moley KH. Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization. Endocrinology. 2012;153:4181-91.
13. Barrett JS, Gearry RB, Muir JG, Irving PM, Rose R, Rosella O, et al. Dietary poorly absorbed, short-chain carbohydrates increase delivery of water and fermentable substrates to the proximal colon. Aliment Pharmacol Ther. 2010;31:874-82.
14. Rao SS, Attaluri A, Anderson L, Stumbo P. Ability of the normal human intestine to absorb fructose: evaluation by breath testing. Clin Gastroenterol Hepatol. 2007;5:959-63. (Pubitemid 47127024)
15. Jones HF, Butler RN, Moore DJ, Brooks DA. Developmental changes and fructose absorption in children: effect on malabsorption testing and dietary management. Nutr Rev. 2013;71: 300-9.
16. Gibson PR, NewnhamE, Barrett JS, Shepherd SJ,Muir JG. Review article: fructose malabsorption and the bigger picture. Aliment Pharmacol Ther. 2007;25:349-63. (Pubitemid 46184448)
17. Barrett JS, Gibson PR. Fructose and lactose testing. Aust Fam Physician. 2012;41:293-6.
18. Shepherd SJ, Gibson PR. Fructose malabsorption and symptoms of irritable bowel syndrome: guidelines for effective dietary management. J Am Diet Assoc. 2006;106:1631-9. (Pubitemid 44415593)
19. Kim Y, Park SC,Wolf BW, Hertzler SR. Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults. Nutr Res. 2011;31:836-41.
20. Komericki P, Akkilic-Materna M, Strimitzer T, Weyermair K, Hammer HF, Aberer W. Oral xylose isomerase decreases breath hydrogen excretion and improves gastrointestinal symptoms in fructose malabsorption-a double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2012;36:980-7.
21. Roberfroid MB. Introducing inulin-type fructans. Br J Nutr. 2005;93 Suppl 1:S13-25. (Pubitemid 43073402)
22. Marcason W. What is the FODMAP diet? J Acad Nutr Diet. 2012;112:1696.
23. Donahue R, Attaluri A, SchneiderM, Valestin J, Rao SS. Absorptive capacity of fructans in healthy humans: a dose response study. Gastroenterology. 2010;138:S709.
24. Muir JG, Shepherd SJ, Rosella O, Rose R, Barrett JS, Gibson PR. Fructan and free fructose content of common Australian vegetables and fruit. J Agric Food Chem. 2007;55:6619-27. (Pubitemid 47280038)
25. Moshfegh AJ, Friday JE, Goldman JP, Ahuja JK. Presence of inulin and oligofructose in the diets of Americans. J Nutr. 1999;129: 14707S-11S.
26. Biesiekierski JR, Rosella O, Rose R, Liels K, Barrett JS, Shepherd SJ, et al. Quantification of fructans, galacto-oligosaccharides and other short-chain carbohydrates in processed grains and cereals. J Hum Nutr Diet. 2011;24:154-176.
27. Shepherd SJ, Parker FC, Muir JG, Gibson PR. Dietary triggers of abdominal symptoms in patients with irritable bowel syndrome: randomized placebo-controlled evidence. Clin Gastroenterol Hepatol. 2008;6:765-71.
28. AttaluriA, Paulson J, JacksonM,Donahue R, Rao SS. Dietary Fructan intolerance: a new recognized problem in IBS. Neurogastroenterol Motil. 2009;57:150.
29. Barrett JS, Gibson PR. Clinical ramifications of malabsorption of fructose and other short-chain carbohydrates. Pract Gastroenterol. 2007;31:51-65. (Pubitemid 47326716)
30. Shepherd SJ, Lomer MC, Gibson PR. Short-chain carbohydrates and functional gastrointestinal disorders. Am J Gastroenterol. 2013;108:707-17.
31. Fernández-Bañares F, Esteve M, Viver JM. Fructose-sorbitol malabsorption. Curr Gastroenterol Rep. 2009;11:368-74.
32. Staudacher HM, Whelan K, Irving PM, Lomer MC. Comparison of symptom response following advice for a diet low in fermentable carbohydrates (FODMAPS) versus standard dietary advice in patients with irritable bowel syndrome. J Hum Nutr Diet. 2011;24:487-95.
33. de Roest RH, Dobbs BR, Chapman BA, Batman B, O'Brien LA, Leeper JA, et al. The low FODMAP diet improves gastrointestinal symptoms in patients with irritable bowel syndrome: a prospective study. Int J Clin Pract. 2013;67:895-903.
34. Halmos EP, Power VA, Shepherd SJ, Gibson PR, Muir JG. A diet low in FODMAPs reduces symptoms of irritable bowel syndrome. Gastroenterology. 2013;pii: S0016-5085(13):01407-8. doi:10.1053/j.gastro.2013.09.046.
35. Ong DK, Mitchell SB, Barrett JS, Shepherd SJ, Irving PM, Biesiekierski JR, et al. Manipulation of dietary short chain carbohydrates alters the pattern of gas production and genesis of symptoms in irritable bowel syndrome. J Gastroenterol Hepatol. 2010;25:1366-73.
36. Halmos EP,Muir JG, Barrett JS, DengM, Shepherd SJ, Gibson PR. Diarrhoea during enteral nutrition is predicted by the poorly absorbed short-chain carbohydrate (FODMAP) content of the formula. Aliment Pharmacol Ther. 2010;32:952-33.
37. Gearry RB, Irving PM, Barrett JS, Nathan DM, Shepherd SJ, Gibson PR. Reduction of dietary poorly absorbed carbohydrates (FODMAPs) improves abdominal symptoms in patients with inflammatory bowel disease-a pilot study. J Crohns Colitis. 2009;3:8-14.
38. Barrett JS. Expanding our knowledge of fermentable, short-chain carbohydrates for managing gastrointestinal symptoms. Nutr Clin Pract. 2013;28:300-6.
39. Barrett JS, Gibson PR. Fermentable oligosaccharides disaccharides, monosaccharides and polyols (FODMAPS) and nonallergic food intolerance: FODMAPs or food chemicals? Ther Adv Gastroenterol. 2012;5:261-8.