Mucosal pre-exposure to Th17-inducing adjuvants exacerbates pathology after influenza infection

American Journal of Pathology

Volumn 184, Issue 1, 2014, Pages 55-63

  Gopal, Radha ^a   Rangel Moreno, Javier ^c   Fallert Junecko, Beth A ^b   Mallon, Daniel J ^a   Chen, Kong ^a   Pociask, Derek A ^a   Connell, Terry D ^d   Reinhart, Todd A ^b   Alcorn, John F ^a   Ross, Ted M ^e   Kolls, Jay K ^a   Khader, Shabaana A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d UNIVERSITY AT BUFFALO   (United States)

^e Vaccine and Gene Therapy Institute of Florida   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; CHEMOKINE; CHOLERA TOXIN; ENTEROTOXIN; INTERLEUKIN 17; TYPE II HEAT LABILE ENTEROTOXIN; UNCLASSIFIED DRUG;

2009 H1N1 INFLUENZA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; CONTROLLED STUDY; DISEASE EXACERBATION; HYPOTHESIS; INFLUENZA A (H5N1); INFLUENZA VIRUS; INFLUENZA VIRUS A H5N1; LUNG INJURY; LUNG PARENCHYMA; MORBIDITY; MOUSE; MUCOSAL IMMUNITY; NEUTROPHIL; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TH17 CELL; VIRUS STRAIN;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; FEMALE; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLUENZA A VIRUS; INFLUENZA VACCINES; INTERLEUKIN-17; MALE; MICE; MICE, INBRED C57BL; MUCOUS MEMBRANE; ORTHOMYXOVIRIDAE INFECTIONS; POLYMERASE CHAIN REACTION; TH17 CELLS;

EID: 84890359329     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.09.012     Document Type: Article

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