메뉴 건너뛰기




Volumn 4, Issue NOV, 2013, Pages

Germline amino acid diversity in B cell receptors is a good predictor of somatic selection pressures

Author keywords

B cells; Diversity; Evolution; Selection; Somatic hypermutation

Indexed keywords

AMINO ACID; B LYMPHOCYTE RECEPTOR;

EID: 84890342244     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00357     Document Type: Article
Times cited : (11)

References (19)
  • 1
    • 0041646843 scopus 로고
    • Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions
    • doi: 10.1073/pnas.79.13.4118
    • Alt FW, Baltimore D. Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions. Proc Natl Acad Sci U S A (1982) 79(13):4118-22. doi: 10.1073/pnas.79.13.4118
    • (1982) Proc Natl Acad Sci U S A , vol.79 , Issue.13 , pp. 4118-4122
    • Alt, F.W.1    Baltimore, D.2
  • 2
    • 0018627375 scopus 로고
    • Sequences at the somatic recombination sites of immunoglobulin light-chain genes
    • doi:10.1038/280288a0
    • Sakano H, Huppi K, Heinrich G, Tonegawa S. Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature (1979) 280(5720):288-94. doi:10.1038/280288a0
    • (1979) Nature , vol.280 , Issue.5720 , pp. 288-294
    • Sakano, H.1    Huppi, K.2    Heinrich, G.3    Tonegawa, S.4
  • 3
    • 0018068687 scopus 로고
    • Rearrangement of genetic information may produce immunoglobulin diversity
    • doi:10.1038/276785a0
    • Weigert M, Gatmaitan L, Loh E, Schilling J, Hood L. Rearrangement of genetic information may produce immunoglobulin diversity. Nature (1978) 276(5690):785-90. doi:10.1038/276785a0
    • (1978) Nature , vol.276 , Issue.5690 , pp. 785-790
    • Weigert, M.1    Gatmaitan, L.2    Loh, E.3    Schilling, J.4    Hood, L.5
  • 4
    • 0019847882 scopus 로고
    • Antibody diversity: somatic hypermutation of rearranged VH genes
    • doi:10.1016/0092-8674(81)90399-8
    • Kim S, Davis M, Sinn E, Patten P, Hood L. Antibody diversity: somatic hypermutation of rearranged VH genes. Cell (1981) 27(3):573-81. doi:10.1016/0092-8674(81)90399-8
    • (1981) Cell , vol.27 , Issue.3 , pp. 573-581
    • Kim, S.1    Davis, M.2    Sinn, E.3    Patten, P.4    Hood, L.5
  • 5
  • 6
    • 0030060366 scopus 로고    scopus 로고
    • Activation and negative selection of functionally distinct subsets of antibody-secreting cells by influenza hemagglutinin as a viral and a neo-self antigen
    • doi:10.1084/jem.183.1.13
    • Caton AJ, Swartzentruber JR, Kuhl AL, Carding SR, Stark SE. Activation and negative selection of functionally distinct subsets of antibody-secreting cells by influenza hemagglutinin as a viral and a neo-self antigen. J Exp Med (1996) 183(1):13-26. doi:10.1084/jem.183.1.13
    • (1996) J Exp Med , vol.183 , Issue.1 , pp. 13-26
    • Caton, A.J.1    Swartzentruber, J.R.2    Kuhl, A.L.3    Carding, S.R.4    Stark, S.E.5
  • 8
    • 0014828908 scopus 로고
    • An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity
    • doi:10.1084/jem.132.2.211
    • Wu TT, Kabat EA. An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity. J Exp Med (1970) 132(2):211-50. doi:10.1084/jem.132.2.211
    • (1970) J Exp Med , vol.132 , Issue.2 , pp. 211-250
    • Wu, T.T.1    Kabat, E.A.2
  • 9
    • 73349126428 scopus 로고    scopus 로고
    • Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells
    • doi:10.4049/jimmunol.0902452
    • Anderson SM, Khalil A, Uduman M, Hershberg U, Louzoun Y, Haberman AM, et al. Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells. J Immunol (2009) 183(11):7314-25. doi:10.4049/jimmunol.0902452
    • (2009) J Immunol , vol.183 , Issue.11 , pp. 7314-7325
    • Anderson, S.M.1    Khalil, A.2    Uduman, M.3    Hershberg, U.4    Louzoun, Y.5    Haberman, A.M.6
  • 10
    • 42949103482 scopus 로고    scopus 로고
    • Improved methods for detecting selection by mutation analysis of Ig V region sequences
    • doi:10.1093/intimm/dxn045
    • Hershberg U, Uduman M, Shlomchik MJ, Kleinstein SH. Improved methods for detecting selection by mutation analysis of Ig V region sequences. Int Immunol (2008) 20(5):683-94. doi:10.1093/intimm/dxn045
    • (2008) Int Immunol , vol.20 , Issue.5 , pp. 683-694
    • Hershberg, U.1    Uduman, M.2    Shlomchik, M.J.3    Kleinstein, S.H.4
  • 11
    • 0031427052 scopus 로고    scopus 로고
    • A Shannon entropy analysis of immunoglobulin and t cell receptor
    • doi:10.1016/S0161-5890(97)00130-2
    • Stewart JJ, Lee CY, Ibrahim S, Watts P, Shlomchik M, Weigert M, et al. A Shannon entropy analysis of immunoglobulin and t cell receptor. Mol Immunol (1997) 34(15):1067-82. doi:10.1016/S0161-5890(97)00130-2
    • (1997) Mol Immunol , vol.34 , Issue.15 , pp. 1067-1082
    • Stewart, J.J.1    Lee, C.Y.2    Ibrahim, S.3    Watts, P.4    Shlomchik, M.5    Weigert, M.6
  • 12
    • 84878854984 scopus 로고    scopus 로고
    • Conserved variation: identifying patterns of stability and variability in BCR and TCR V genes with different diversity and richness metrics
    • doi:10.1088/1478-3975/10/3/035005
    • Schwartz GW, Hershberg U. Conserved variation: identifying patterns of stability and variability in BCR and TCR V genes with different diversity and richness metrics. Phys Biol (2013) 10(3):1-10. doi:10.1088/1478-3975/10/3/035005
    • (2013) Phys Biol , vol.10 , Issue.3 , pp. 1-10
    • Schwartz, G.W.1    Hershberg, U.2
  • 13
    • 55949092569 scopus 로고    scopus 로고
    • IMGTâ®, the international ImMunoGeneTics information systemâ® for immunoinformatics. Methods for querying IMGTâ® databases, tools and webresources in the context of immunoinformatics
    • doi:10.1007/s12033-008-9062-7
    • Lefranc M-P. IMGTâ®, the international ImMunoGeneTics information systemâ® for immunoinformatics. Methods for querying IMGTâ® databases, tools and webresources in the context of immunoinformatics. Mol Biotechnol (2008) 40(1):101-11. doi:10.1007/s12033-008-9062-7
    • (2008) Mol Biotechnol , vol.40 , Issue.1 , pp. 101-111
    • Lefranc, M.-P.1
  • 14
    • 84874095196 scopus 로고    scopus 로고
    • Age-related changes in human peripheral blood IGH repertoire following vaccination
    • doi:10.3389/fimmu.2012.00193
    • Wu Y, Kipling D, Dunn-Walters DK. Age-related changes in human peripheral blood IGH repertoire following vaccination. Front Immunol (2012) 3:193. doi:10.3389/fimmu.2012.00193
    • (2012) Front Immunol , vol.3 , pp. 193
    • Wu, Y.1    Kipling, D.2    Dunn-Walters, D.K.3
  • 15
    • 0000917309 scopus 로고
    • Explicit calculation of the rarefaction diversity measurement and the determination of sufficient sample size
    • doi:10.2307/1934716
    • Heck LK, van Belle G, Simberloff D. Explicit calculation of the rarefaction diversity measurement and the determination of sufficient sample size. Ecology (1975) 56(6):1459-61. doi:10.2307/1934716
    • (1975) Ecology , vol.56 , Issue.6 , pp. 1459-1461
    • Heck, L.K.1    van Belle, G.2    Simberloff, D.3
  • 16
    • 33750441823 scopus 로고    scopus 로고
    • Differences in potential for amino acid change following mutation reveals distinct strategies for kappa and lambda light-chain variation
    • doi:10.1073/pnas.0607581103
    • Hershberg U, Shlomchik MJ. Differences in potential for amino acid change following mutation reveals distinct strategies for kappa and lambda light-chain variation. Proc Natl Acad Sci U S A (2006) 103(43):15963-8. doi:10.1073/pnas.0607581103
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.43 , pp. 15963-15968
    • Hershberg, U.1    Shlomchik, M.J.2
  • 17
    • 0000006498 scopus 로고
    • Diversity and evenness: a unifying notation and its consequences
    • doi:10.2307/1934352
    • Hill M. Diversity and evenness: a unifying notation and its consequences. Ecology (1973) 54(2):427-32. doi:10.2307/1934352
    • (1973) Ecology , vol.54 , Issue.2 , pp. 427-432
    • Hill, M.1
  • 18
    • 33646876613 scopus 로고    scopus 로고
    • Entropy and diversity
    • doi:10.1111/j.2006.0030-1299.14714.x
    • Jost L. Entropy and diversity. Oikos (2006) 113(2):363-75. doi:10.1111/j.2006.0030-1299.14714.x
    • (2006) Oikos , vol.113 , Issue.2 , pp. 363-375
    • Jost, L.1
  • 19
    • 0032080047 scopus 로고    scopus 로고
    • Structural determinants in the sequences of immunoglobulin variable domain
    • doi:10.1006/jmbi.1998.1653
    • Chothia C, Gelfand I, Kister A. Structural determinants in the sequences of immunoglobulin variable domain. J Mol Biol (1998) 278(2):457-79. doi:10.1006/jmbi.1998.1653
    • (1998) J Mol Biol , vol.278 , Issue.2 , pp. 457-479
    • Chothia, C.1    Gelfand, I.2    Kister, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.