The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition

Journal of Biological Chemistry

Volumn 288, Issue 50, 2013, Pages 35637-35650

  Lu, Li ^a,c   Hu, Shaohua ^a   Wei, Rongfei ^a,d   Qiu, Xiao ^a,d   Lu, Kefeng ^a   Fu, Yesheng ^a   Li, Hongchang ^a   Xing, Guichun ^a   Li, Dong ^a   Peng, Ruiyun ^a   He, Fuchu ^a,c,d   Zhang, Lingqiang ^a,b  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c BEIJING UNIVERSITY OF TECHNOLOGY   (China)

^d TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE-PROMOTING COMPLEX/CYCLOSOME; CANDIDATE LIST; IMMUNOPRECIPITATIONS; MITOTIC SPINDLE; OVER-EXPRESSION; POTENTIAL PROTEINS; TRANSCRIPTIONAL ACTIVITY; UBIQUITIN LIGASES;

MASS SPECTROMETRY;

PROTEINS;

ANAPHASE PROMOTING COMPLEX; MESSENGER RNA; PROTEIN NEDL2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; UVOMORULIN;

ANAPHASE; ARTICLE; CARCINOGENESIS; CHROMOSOME; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME DEGRADATION; ENZYME SUBSTRATE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; METAPHASE; MITOSIS; MITOSIS SPINDLE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM;

APC/C; CELL CYCLE; MITOSIS; PROTEIN DEGRADATION; TUMOR; UBIQUITIN LIGASE;

AMINO ACID MOTIFS; ANAPHASE; ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; CADHERINS; CARCINOGENESIS; CELL LINE; CHROMOSOME ABERRATIONS; ENZYME ACTIVATION; HUMANS; METAPHASE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEOLYSIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SPINDLE APPARATUS; TIME FACTORS; UBIQUITIN-PROTEIN LIGASES;

EID: 84890331214     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.472076     Document Type: Article

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