A chinese medicine, kuan-sin-yin decoction, improves liver function in hepatitis b virus carriers: A randomized, controlled study

Journal of Alternative and Complementary Medicine

Volumn 19, Issue 12, 2013, Pages 964-969

  Lee, Chia Jung ^a,b   Cheng, Chen Hung ^c   Li, Yu Hsien ^c   Liu, Chia Yu ^a,c   Hsu, Chung Hua ^a,c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b I SHOU UNIVERSITY   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AGASTACHE RUGOSA EXTRACT; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ASTRAGALUS MEMBRANACEUS EXTRACT; ATRACTYLODES MACROCEPHALA EXTRACT; CODONOPSIS PILOSULA EXTRACT; GLYCYRRHIZA URALENSIS EXTRACT; HEPATITIS B(E) ANTIGEN; KUAN SIN YIN DECOCTION; LIGUSTRUM LUCIDUM EXTRACT; PLANT EXTRACT; PORIA COCOS EXTRACT; UNCLASSIFIED DRUG; VIRUS DNA;

ADULT; AGASTACHE; AGASTACHE RUGOSA; ARTICLE; ASTRAGALUS MEMBRANACEUS; ATRACTYLODES; ATRACTYLODES MACROCEPHALA; CHINESE MEDICINE; CODONOPSIS PILOSULA; CONSTIPATION; CONTROLLED STUDY; DRUG EFFICACY; EVENING DOSAGE; FEMALE; FRUIT; GLYCYRRHIZA URALENSIS; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIGUSTRUM; LIGUSTRUM LUCIDUM; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PLANT LEAF; PLANT ROOT; PLANT STEM; PORIA COCOS; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RHIZOME; SCLEROTIUM (ASCOMYCOTA); SEROCONVERSION; SHORT FROM 12; TAIWAN; TREATMENT RESPONSE; VIRUS CARRIER; WORLD HEALTH ORGANIZATION QUALITY OF LIFE BRIEF VERSION;

ADULT; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; CARRIER STATE; DNA, VIRAL; DRUGS, CHINESE HERBAL; FEMALE; HEPATITIS B; HUMANS; LIVER; MALE; MIDDLE AGED; QUALITY OF LIFE; VIRAL LOAD;

EID: 84890319255     PISSN: 10755535     EISSN: 15577708     Source Type: Journal    
DOI: 10.1089/acm.2013.0136     Document Type: Article

References (28)

1. World Health Organization. Hepatitis B. World Health Organization Fact Sheet 204 (Revised July 2012) [homepage on the Internet]. WHO Web site. 2012. Online document at: Http://www.who.int/mediacentre/factsheets/fs204/en/index. html Accessed July 2012.
2. Lok AS. Chronic hepatitis B. N Engl J Med 2002;346:1682-1683.
3. Mcglynn KA, Tsao L, Hsing AW, et al. International trends and patterns of primary liver cancer. Int J Cancer 2001;94: 290-296.
4. Lemon SM, Layden TJ, Seeff L, et al. The 20th United States Japan Joint Hepatitis Panel Meeting. Hepatology 2000;31: 800-806.
5. Chen Y, Cheng G, Mahato RI. RNAi for treating hepatitis B viral infection. Pharm Res 2008;25:72-86.
6. Kim JW, Lee HS, Woo GH, Yoon JH, Jang JJ, Chi JG, Kim CY. Fatal submassive hepatic necrosis associated with Tyrosinemethionine-aspartate- aspartate-motif mutation of hepatitis B virus after long-term lamivudine therapy. Clin Infect Dis 2001;33:403-405.
7. Zhang L, Wang G, Hou W, et al. Contemporary clinical research of traditional Chinese medicines for chronic hepatitis B in China: An analytic review. Hepatology 2010;51: 690-698.
8. Cui X, Wang Y, Kokudo N, et al. Traditional Chinese medicine and related compounds against hepatitis B infection. Biosci Trends 2010;4:39-47.
9. Yang ZC, Yang SH, Yang SS, Chen DS. A hospital-based study on the use of alternative medicine in patients with chronic liver and gastrointestinal diseases. Am J Chin Med 2002;30:637-643.
10. Liu J, Manheimer E, Tsutani K, Gluud C. Medicinal herbs for hepatitis C virus infection, a cochrane hepatobiliary systemic review of randomized trials. Am J Gastroenterol 2003;98: 538-544.
11. Chou CC, Pan SL, Teng CM, Guh JH. Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells. Eur J Pharm Sci 2003;9:403-412.
12. Mcculloch M, Broffman M, Gao J, Colford JM Jr. Chinese herbal medicine and interferon in the treatment of chronic hepatitis B: A meta-analysis of randomized, controlled trials. Am J Public Health 2002;92:1619-1627.
13. Zhang W, Wang LQ, Liu YB. Evaluation on quality of life and analysis on its correlation with TCM syndromes in patients of chronic hepatitis B. Chin J Integr Med 2009;15:30-33.
14. Gutteling JJ, Man RA, Busschbach JJ, Darlington AS. Overview of research on health-related quality of life in patients with chronic liver disease. Neth J Med 2007;65: 227-234.
15. Yao G, Chung CW, Yu CF, Wang JD. Development and verification of validity and reliability of the WHOQOL-BREF Taiwan version. J Formos Med Assoc 2002;101:342-351.
16. Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: Construction of scales and preliminary tests of reliability and validity. Med Care 1996;34:220-233.
17. Sun YX. Immunological adjuvant effect of a water-soluble polysaccharide, CPP, from the roots of Codonopsis pilosula on the immune responses to ovalbumin in mice. Chem Biodivers 2009;6:890-896.
18. Jin C, Zhang PJ, Bao CQ, et al. Protective effects of Atractylodes macrocephala polysaccharide on liver ischemia-reperfusion injury and its possible mechanism in rats. Am J Chin Med 2011;39:489-502.
19. Chang HH, Yeh CH, Sheu F. A novel immunomodulatory protein from Poria cocos induces Toll-like receptor 4-dependent activation within mouse peritoneal macrophages. J Agric Food Chem 2009;57:6129-639.
20. Feng C, Wang H, Yao C, Zhang J, Tian Z. Diammonium glycyrrhizinate, a component of traditional Chinese medicine Gan-Cao, prevents murine T-cell-mediated fulminant hepatitis in IL-10-and IL-6-dependent manners. Int Immunopharmacol 2007;7:1292-1298.
21. Chao WW, Kuo YH, Li WC, Lin BF. The production of nitric oxide and prostaglandin E2 in peritoneal macrophages is inhibited by Andrographis paniculata, Angelica sinensis, and Morus alba ethyl acetate fractions. J Ethnopharmacol 2009; 122: 68-75.
22. Oh HM, Kang YJ, Kim SH, et al. Agastache rugosa leaf extract inhibits the iNOS expression in ROS 17/2.8 cells activated with TNF-alpha and IL-1beta. Arch Pharm Res 2005; 28:305-310.
23. Lin HM, Yen FL, Ng LT, Lin CC.Protective effects of Ligustrum lucidum fruit extract on acute butylated hydroxytoluene-induced oxidative stress in rats. J Ethnopharmacol 2007;111:129-136.
24. Cui X, Wang Y, Kokudo N, et al. Traditional Chinese medicine and related active compounds against hepatitis B virus infection. Biosci Trends 2010;4:39-47.
25. Mehta DH, Gardiner PM, Phillips RS, McCarthy EP. Herbal and dietary supplement disclosure to health care providers by individuals with chronic conditions. J Altern Complement Med 2008;14:1263-1269.
26. Tang LL, Sheng JF, Xu CH, Liu KZ. Clinical and experimental effectiveness of Astragali compound in the treatment of chronic viral hepatitis B. J Int Med Res 2009;37: 662-667.
27. Liu P, Hu YY, Liu C, et al. Multicenter clinical study on Fuzhenghuayu capsule against liver fibrosis due to chronic hepatitis B. World J Gastroenterol 2005;11:2892-2899.
28. Marcellin P, Lau GK, Zeuzem S, et al. Comparing the safety, tolerability and quality of life in patients with chronic hepatitis B vs chronic hepatitis C treated with peginterferon alpha-2a. Liver Int 2008;28:477-485.