Characterization of suspected illegal skin whitening cosmetics

Journal of Pharmaceutical and Biomedical Analysis

Volumn 90, Issue , 2014, Pages 85-91

  Desmedt, B ^a,b   Van Hoeck, E ^a   Rogiers, V ^b   Courselle, P ^a   De Beer, J O ^a   de Paepe, K ^b   Deconinck, E ^a  

^a SCIENTIFIC INSTITUTE OF PUBLIC HEALTH   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Bleaching; Corticosteroids; Hydroquinone; Lightening; ToF

Indexed keywords

ARBUTIN; BETAMETHASONE DIPROPIONATE; BETAMETHASONE VALERATE; CLOBETASOL PROPIONATE; CORTICOSTEROID; COSMETIC; DEPIGMENTING AGENT; DEXAMETHASONE; FLUOCINOLONE ACETONIDE; HYDROCORTISONE ACETATE; HYDROQUINONE; ILLICIT DRUG; KOJIC ACID; NICOTINAMIDE; RETINOIC ACID; SALICYLIC ACID;

ARTICLE; BLEACHING; CONTROLLED STUDY; DRUG LEGISLATION; DRUG MARKETING; HEALTH HAZARD; PRIORITY JOURNAL; SCREENING; SKIN; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BLEACHING; CORTICOSTEROIDS; HYDROQUINONE; LIGHTENING; TOF;

BELGIUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLOBETASOL; COSMETICS; DERMATOLOGIC AGENTS; EUROPEAN UNION; GLUCOCORTICOIDS; HUMANS; HYDROQUINONES; LEGISLATION, DRUG; MASS SPECTROMETRY; SKIN LIGHTENING PREPARATIONS; TRETINOIN;

EID: 84890284069     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.11.024     Document Type: Article

References (21)

1. AlGhamdi K. The use of topical bleaching agents among women: a cross-sectional study of knowledge, attitude and practices. J. Eur. Acad. Dermatol. Venereol. 2010, 24:1214-1219.
2. Hall R.E. The Bleaching Syndrome: western civilization vis-à-vis inferiorized people of color. The Melanin Millennium 2013, 348. Springer, Dordrecht. R.E. Hall (Ed.).
3. EU Regulation 1223/2009 Of the European parliament and of the Council of 30 November 2009. Official J 2009, L 342/59.
4. Mahe A.A., Ly F., Aymard G., Dangou J. Skin diseases associated with the cosmetic use of bleaching products in women from Dakar, Senegal. Br. J. Dermatol. 2003, 493-500.
5. Karamagi C., Owino E., Katabira E. Hydroquinone neuropathy following use of skin bleaching creams: case report. East Afr. Med. J. 2001, 78:223-224.
6. SCCNFP SCCNFP/0522/01, concerning on salicylic acid, SCCNFP/0522/01. Adopted during the 20th Plenary Meeting of 4 June 2002 2002.
7. Bashir S., Dreher F., Chew A., Zhai H., Levin C., Stern R., Maibach H. Cutaneous bioassay of salicylic acid as a keratolytic. Int. J. Pharm. 2005, 292:187-194.
8. RAPEX notification,, 09-2013. http://ec.europa.eu/consumers/dyna/rapex/rapex_archives_en.cfm.
9. Desmedt B., Rogiers V., Courselle P., De Beer J., De Paepe K., Deconinck E. Development and validation .of a fast chromatographic method for screening and quantification of legal and illegal skin whitening agents. J. Pharm. Biomed. Anal. 2013, 83:82-88.
10. SCCNFP SCCNFP/0486/01, the use of benzoyl peroxide (BPO) hydroquinone (HQ), hydroquinone methylether (MEHQ) in artificial nail systems. Adopted during the SCCNFP 20th Plenary Meeting of 4 June 2002 2002.
11. SCCS SCCS/1481/12: draft opinion on kojic acid. Adopted Opinion during the 15th Plenary Meeting of 26-27 June 2012 2012.
12. SCCP SCCP/1158/08: opinion on β-arbutin, SCCP/1158/08. Adopted Opinion during the 15th Plenary Meeting of 15 April 2008 2008.
13. SANCO, N° SANCO/12495/2011 Method validation and quality control procedures for pesticide residues analysis in food and feed 2012.
14. CRLs Community reference laboratories residues, guidelines for the validation of screening methods for residues of veterinary medicines 2010.
15. European Pharmacopeia 2012, Council of Europe, Strasbourg,, 09-2013. http://online.pheur.org/, 7th ed.
16. BCFI, medication formulary FAMHP 2013,, 09-2013. http://www.bcfi.be/, 26th ed.
17. Martindale the Complete Drug Reference 2013, Pharmaceutical Press, London, (08.08.13). http://www.medicinescomplete.com/.
18. Ladizinski B., Mistry N., Kundu R.V. Widespread use of toxic skin lightening compounds: medical and psychosocial aspects. Dermatol. Clin. 2011, 29:111-123.
19. Mahé A., Perret J., Ly F., Fall F., Rault J., Dumont A. The cosmetic use of skin-lightening products during pregnancy in Dakar Senegal: a common and potentially hazardous practice. Trans. R. Soc. Trop. Med. Hyg. 2007, 101:183-187.
20. Briganti S., Ottaviani M., Picardo M. Chemical, pharmacologic and physical agents causing hypomelanoses. The Pigmentary System 2006, 669. Wiley-Blackwell, Oxford. J. Nordlund, R.E. Boissy, V.J. Hearing (Eds.).
21. Druce M., Goldstone A.P., Tan T.M., Meeran K. The pursuit of beauty. Lancet 2008, 371:596-696.