Endocannabinoids as markers of sperm quality: Hot spots

Frontiers in Endocrinology

Volumn 4, Issue NOV, 2013, Pages

  Maccarrone, Mauro ^a,b  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

Cholesterol; Chromatin; Epigenetic regulation; Lipid rafts; Receptors

Indexed keywords

EID: 84890254795     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2013.00169     Document Type: Article

References (25)

1. Lewis SE, Maccarrone M. Endocannabinoids, sperm biology and human fertility. Pharmacol Res (2009) 60:126-31. doi:10.1016/j.phrs.2009.02.009
2. Schuel H, Burkman LJ, Lippes J, Crickard K, Forester E, Piomelli D, et al. N-Acylethanolamines in human reproductive fluids. Chem Phys Lipids (2002) 121:211-27. doi:10.1016/S0009-3084(02)00158-5
3. Wang H, Dey SK, Maccarrone M. Jekyll and hyde: two faces of cannabinoid signaling in male and female fertility. Endocr Rev (2006) 27:427-48. doi:10.1210/er.2006-0006
4. Maccarrone M. Endocannabinoids: friends and foes of reproduction. Prog Lipid Res (2009) 48:344-54. doi:10.1016/j.plipres.2009.07.001
5. Bari M, Battista N, Pirazzi V, Maccarrone M. The manifold actions of endocannabinoids on female and male reproductive events. Front Biosci (2011) 16:498-416. doi:10.2741/3701
6. Di Marzo V, De Petrocellis L. Endocannabinoids as regulators of transient receptor potential (TRP) channels: a further opportunity to develop new endocannabinoid-based therapeutic drugs. Curr Med Chem (2010) 17:1430-49. doi:10.2174/092986710790980078
7. Barbonetti A, Vassallo MR, Fortunato D, Francavilla S, Maccarrone M, Francavilla F. Energetic metabolism and human sperm motility: impact of CB1 receptor activation. Endocrinology (2010) 151:5882-92. doi:10.1210/en.2010-0484
8. Bénard G, Massa F, Puente N, Lourenço J, Bellocchio L, Soria-Gómez E, et al. Mitochondrial CB1 receptors regulate neuronal energy metabolism. Nat Neurosci (2012) 15:558-64. doi:10.1038/nn.3053
9. Morozov YM, Dominguez MH, Varela L, Shanabrough M, Koch M, Horvath TL, et al. Antibodies to cannabinoid type 1 receptor co-react with stomatin-like protein 2 in mouse brain mitochondria. Eur J Neurosci (2013) 38:2341-8. doi:10.1111/ejn.12237
10. Francavilla F, Battista N, Barbonetti A, Vassallo MR, Rapino C, Antonangelo C, et al. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. Endocrinology (2009) 150:4692-700. doi:10.1210/en.2009-0057
11. Lewis SE, Rapino C, Di Tommaso M, Pucci M, Battista N, Paro R, et al. Differences in the endocannabinoid system of sperm from fertile and infertile men. PLoS One (2012) 7:e47704. doi:10.1371/journal.pone.0047704
12. Amoako AA, Marczylo TH, Marczylo EL, Elson J, Willets JM, Taylor AH, et al. Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia. Hum Reprod (2013) 28:2058-66. doi:10.1093/humrep/det232
13. Flesch FM, Brouwers JF, Nievelstein PF, Verkleij AJ, van Golde LM, Colenbrander B, et al. Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. J Cell Sci (2001) 114(19):3543-55.
14. Miranda PV, Allaire A, Sosnik J, Visconti PE. Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm. Biol Reprod (2009) 80:897-904. doi:10.1095/biolreprod.108.075242
15. Botto L, Bernabò N, Palestini P, Barboni B. Bicarbonate induces membrane reorganization and CBR1 and TRPV1 endocannabinoid receptor migration in lipid microdomains in capacitating boar spermatozoa. J Membr Biol (2010) 238:33-41. doi:10.1007/s00232-010-9316-8
16. Dainese E, Oddi S, Maccarrone M. Interaction of endocannabinoid receptors with biological membranes. Curr Med Chem (2010) 17:1487-99. doi:10.2174/092986710790980087
17. Ambrosini A, Zolese G, Wozniak M, Genga D, Boscaro M, Mantero F, et al. Idiopathic infertility: susceptibility of spermatozoa to in-vitro capacitation, in the presence and the absence of palmitylethanolamide (a homologue of anandamide), is strongly correlated with membrane polarity studied by Laurdan fluorescence. Mol Hum Reprod (2003) 9:381-8. doi:10.1093/molehr/gag056
18. Ambrosini A, Zolese G, Ambrosi S, Bertoli E, Mantero F, Boscaro M, et al. Idiopathic infertility: effect of palmitoylethanolamide (a homologue of anandamide) on hyperactivated sperm cell motility and Ca2+ influx. J Androl (2005) 26:429-36. doi:10.2164/jandrol.04141
19. Bian X, Gandahi JA, Liu Y, Yang P, Liu Y, Zhang L, et al. The ultrastructural characteristics of the spermatozoa stored in the cauda epididymidis in Chinese soft-shelled turtle Pelodiscus sinensis during the breeding season. Micron (2013) 44:202-9. doi:10.1016/j.micron.2012.06.010
20. Oddi S, Fezza F, Pasquariello N, De Simone C, Rapino C, Dainese E, et al. Evidence for the intracellular accumulation of anandamide in adiposomes. Cell Mol Life Sci (2008) 65:840-50. doi:10.1007/s00018-008-7494-7
21. Maccarrone M, Dainese E, Oddi S. Intracellular trafficking of anandamide: new concepts for signaling. Trends Biochem Sci (2010) 35:601-8. doi:10.1016/j.tibs.2010.05.008
22. Chioccarelli T, Cacciola G, Altucci L, Lewis SE, Simon L, Ricci G, et al. Cannabinoid receptor 1 influences chromatin remodeling in mouse spermatids by affecting content of transition protein 2 mRNA and histone displacement. Endocrinology (2010) 151:5017-29. doi:10.1210/en.2010-0133
23. D'Addario C, Di Francesco A, Pucci M, Finazzi Agrò A, Maccarrone M. Epigenetic mechanisms and endocannabinoid signalling. FEBS J (2013) 280:1905-17. doi:10.1111/febs.12125
24. Battista N, Meccariello R, Cobellis G, Fasano S, Di Tommaso M, Pirazzi V, et al. The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. Mol Cell Endocrinol (2012) 355:1-14. doi:10.1016/j.mce.2012.01.014
25. Liu J, Liu X, Duan K, Zhang Y, Guo SW. The expression and functionality of transient receptor potential vanilloid 1 in ovarian endometriomas. Reprod Sci (2012) 19:1110-24. doi:10.1177/1933719112443876