Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column

Biomedical Chromatography

Volumn 28, Issue 1, 2014, Pages 152-158

  Toribio, L ^a   Bernal, J L ^a   Martin M T ^a   Bernal, J ^a   del Nozal, M J ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

Chiral separation; Chiralpak AD; Imidazoles and triazoles; Modifier effect; SFC; Temperature effect

Indexed keywords

ACETONITRILE; CHIRALITY; COLUMN CHROMATOGRAPHY; EFFLUENT TREATMENT; ENANTIOMERS; ETHANOL; GAS CHROMATOGRAPHY; STEREOCHEMISTRY; SUPERCRITICAL FLUIDS; TEMPERATURE;

CHIRAL SEPARATIONS; CHIRALPAK AD; ENANTIOMERIC SEPARATION; IMIDAZOL; IMIDAZOLE AND TRIAZOLE; MODIFIER EFFECT; ORGANIC MODIFIER; SFC; SUPER CRITICAL FLUID CHROMATOGRAPHY; SUPERCRITICAL FLUID CHROMATOGRAPHY;

METHANOL;

2 PROPANOL; ACETONITRILE; ALCOHOL; AROMATIC COMPOUND; BIFONAZOLE; CARBON OXYGEN MONOCYCLE; ECONAZOLE; ENILCONAZOLE; IMIDAZOLE DERIVATIVE; KETOCONAZOLE; METHANOL; MICONAZOLE; ORGANIC COMPOUND; SULCONAZOLE; TRIAZOLE DERIVATIVE;

ANALYTICAL EQUIPMENT; ARTICLE; CONTROLLED STUDY; ENANTIOMER; ENTHALPY; ENTROPY; SEPARATION TECHNIQUE; SUPERCRITICAL FLUID CHROMATOGRAPHY; TEMPERATURE SENSITIVITY;

CHIRAL SEPARATION; CHIRALPAK AD; IMIDAZOLES AND TRIAZOLES; MODIFIER EFFECT; SFC; TEMPERATURE EFFECT;

AMYLOSE; AZOLES; CHROMATOGRAPHY, SUPERCRITICAL FLUID; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; PHENYLCARBAMATES; STEREOISOMERISM; TEMPERATURE;

EID: 84890232849     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3013     Document Type: Article

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