Supramolecular high-aspect ratio assemblies with strong antifungal activity

Nature Communications

Volumn 4, Issue , 2013, Pages

  Fukushima, Kazuki ^a,b   Liu, Shaoqiong ^c   Wu, Hong ^c   Engler, Amanda C ^a   Coady, Daniel J ^a   Maune, Hareem ^a   Pitera, Jed ^a   Nelson, Alshakim ^a   Wiradharma, Nikken ^c   Venkataraman, Shrinivas ^c   Huang, Yuan ^d   Fan, Weimin ^d   Ying, Jackie Y ^c   Yang, Yi Yan ^c   Hedrick, James L ^a  

^a IBM ALMADEN RESEARCH CENTER   (United States)

^b YAMAGATA UNIVERSITY   (Japan)

^c INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; EYE DROPS; FLUCONAZOLE;

ANTIMICROBIAL ACTIVITY; BIOFILM; CATION; DRUG RESISTANCE; FUNGUS; PATHOGEN; POLYMER; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIFUNGAL ACTIVITY; ANTIFUNGAL RESISTANCE; ARTICLE; ATOMIC FORCE MICROSCOPY; BROTH DILUTION; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG ISOLATION; FIBROBLAST; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATOMYCOSIS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR RECOGNITION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; RAT; SCANNING ELECTRON MICROSCOPY; STATIC ELECTRICITY; SUPRAMOLECULAR CHEMISTRY; TOPICAL TREATMENT; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANTIFUNGAL AGENTS; BIOFILMS; CANDIDA ALBICANS; POLYMERS;

EID: 84890193161     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3861     Document Type: Article

References (23)

1. Ostrosky-Zeichner, L., Casadevall, A., Galgiani, J. N., Odds, F. C. & Rex, J. H. An insight into the antifungal pipeline: selected new molecules and beyond. Nat. Rev. Drug Discov. 9, 719-727 (2010).
2. Berman, J. & Sudbery, P. E. Candida albicans: a molecular revolution built on lessons from budding yeast. Nat. Rev. Genet. 3, 918-930 (2002). (Pubitemid 35423504)
3. Wisplinghoff, H. et al. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin. Infect. Dis. 39, 309-317 (2004). (Pubitemid 39050477)
4. Anderson, J. B. Evolution of antifungal-drug resistance: Mechanisms and pathogen fitness. Nat. Rev. Microbiol. 3, 547-556 (2005). (Pubitemid 40903878)
5. Cowen, L. E. The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype. Nat. Rev. Microbiol. 6, 187-198 (2008). (Pubitemid 351256314)
6. Hartsel, S. & Bolard, J. Amphotericin B: new life for an old drug. Trends Pharmacol. Sci. 17, 445-449 (1996). (Pubitemid 27028476)
7. Fanos, V. & Cataldi, L. Amphotericin B-induced nephrotoxicity: a review. J. Chemother. 12, 463-470 (2000). (Pubitemid 32048160)
8. Brogden, K. A. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol. 3, 238-250 (2005). (Pubitemid 40298223)
9. Nederberg, F. et al. Biodegradable nanostructures with selective lysis of microbial membranes. Nat. Chem. 3, 409-414 (2011).
10. Liu, L. H. et al. Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent. Nat. Nanotech. 4, 457-463 (2009).
11. Qiao, Y. et al. Highly dynamic biodegradable micelles capable of lysing Grampositive and Gram-negative bacterial membrane. Biomaterials 33, 1146-1153 (2011).
12. Silva, A. D. et al. A fundamental study on dissolution behavior of highresolution molecular glass photoresists. Chem. Mater. 20, 7292-7300 (2008).
13. Klepser, M. E., Ernst, E. J., Lewis, R. E., Ernst, M. E. & Pfaller, M. A. Influence of test conditions on antifungal time-kill curve results: proposal for standardized methods. Antimicrob. Agents Chemother. 42, 1207-1212 (1998). (Pubitemid 28227921)
14. Rex, J. H. et al. Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro in vivo correlation data for fluconazole, itraconazole, and Candida infections. Clin. Infect. Dis. 24, 235-247 (1997). (Pubitemid 127774263)
15. Douglas, L. J. Candida biofilms and their role in infection. Trends Microbiol. 11, 30-36 (2003). (Pubitemid 36084353)
16. Finkel, J. S. & Mitchell, A. P. Genetic control of Candida albicans biofilm development. Nat. Rev. Microbiol. 9, 109-118 (2011).
17. Chandra, J., Mukherjee, P. K. & Ghannoum, M. A. In vitro growth and analysis of Candida biofilms. Nat. Protoc. 3, 1909-1924 (2008).
18. Chen, C. Z. & Cooper, S. L. Interactions between dendrimer biocides and bacterial membranes. Biomaterials 23, 3359-3368 (2002). (Pubitemid 34615642)
19. Goldblum, D., Frueh, B. E., Sarra, G. M., Katsoulis, K. & Zimmerli, S. Topical caspofungin for treatment of keratitis caused by Candida albicans in a rabbit model. Antimicrob. Agents Chemother. 49, 1359-1363 (2005). (Pubitemid 40463362)
20. Wu, T. G., Wilhelmus, K. R. & Mitchell, B. M. Experimental keratomycosis in a mouse model. Invest. Ophthalmol. Vis. Sci. 44, 210-216 (2003). (Pubitemid 36134277)
21. Keay, L. et al. Microbial keratitis: Predisposing factors and morbidity. Ophthalmology 113, 109-116 (2006). (Pubitemid 43021736)
22. Wiegand, I., Hilpert, K. & Hancock, R. E. W. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat. Protoc. 3, 163-175 (2008). (Pubitemid 351266501)
23. Dzidic, S., Suskovic, J. & Kos, B. Antibiotic resistance mechanisms in bacteria: biochemical and genetic aspects. Food Technol. Biotechnol. 46, 11-21 (2008). (Pubitemid 351767991)