Genetic prediction of quantitative lipid traits: Comparing shrinkage models to gene scores

Genetic Epidemiology

Volumn 38, Issue 1, 2014, Pages 72-83

  Warren, Helen ^a   Casas, Juan Pablo ^a,b   Hingorani, Aroon ^b   Dudbridge, Frank ^a   Whittaker, John ^a,c  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Lipids; Penalised regression; Polygenic score; Prediction; SNP selection

Indexed keywords

APOLIPOPROTEIN E; HIGH DENSITY LIPOPROTEIN; LIPID; LOW DENSITY LIPOPROTEIN;

ADULT; AGED; ALLELE; ARTICLE; FEMALE; GENETIC LINKAGE; GENETIC VARIABILITY; GENOTYPE; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PREDICTIVE VALUE; QUANTITATIVE TRAIT; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

LIPIDS; PENALISED REGRESSION; POLYGENIC SCORE; PREDICTION; SNP SELECTION;

CHOLESTEROL, HDL; CHOLESTEROL, LDL; COHORT STUDIES; FEMALE; GENES; GENOTYPE; GREAT BRITAIN; HEALTH SURVEYS; HEART; HUMANS; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; REGRESSION ANALYSIS; SAMPLE SIZE;

EID: 84890144067     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.21777     Document Type: Article

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