Highly active modulators of indole signaling alter pathogenic behaviors in gram-negative and gram-positive bacteria

Chemistry - A European Journal

Volumn 19, Issue 51, 2013, Pages 17595-17602

  Minvielle, Marine J ^a   Eguren, Kristen ^a   Melander, Christian ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

desformylflustrabromine; mechanistic probes; natural products; phenotype control; structure activity relationships

Indexed keywords

ANTIBIOTIC RESISTANCE; DESFORMYLFLUSTRABROMINE; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIUM; MECHANISTIC PROBES; NATURAL PRODUCTS; STRUCTURE ACTIVITY RELATIONSHIPS; TRANSCRIPTIONAL REGULATOR;

ACID RESISTANCE; AMINO ACIDS; ANTIBIOTICS; BACTERIA; BIOFILMS; MOLECULES; PROBES; SCAFFOLDS (BIOLOGY);

POLYCYCLIC AROMATIC HYDROCARBONS;

BACTERIAL PROTEIN; BROMINATED HYDROCARBON; DESFORMYLFLUSTRABROMINE; INDOLE; INDOLE ALKALOID; INDOLE DERIVATIVE; SDIA PROTEIN, BACTERIA; TRANSACTIVATOR PROTEIN; TRYPTOPHANASE;

ARTICLE; BIOFILM; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MECHANISTIC PROBES; METABOLISM; NATURAL PRODUCTS; PHENOTYPE; PHENOTYPE CONTROL; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE-ACTIVITY RELATIONSHIPS; SYNTHESIS; TEMPERATURE;

DESFORMYLFLUSTRABROMINE; MECHANISTIC PROBES; NATURAL PRODUCTS; PHENOTYPE CONTROL; STRUCTURE-ACTIVITY RELATIONSHIPS;

BACTERIAL PROTEINS; BIOFILMS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HYDROCARBONS, BROMINATED; INDOLE ALKALOIDS; INDOLES; PHENOTYPE; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; TRANS-ACTIVATORS; TRYPTOPHANASE;

EID: 84890124399     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201303510     Document Type: Article

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