Alpinetin inhibits LPS-induced inflammatory mediator response by activating PPAR-γ in THP-1-derived macrophages

European Journal of Pharmacology

Volumn 721, Issue 1-3, 2013, Pages 96-102

  Hu, Ke ^b   Yang, Yu ^a   Tu, Qiuyun ^b   Luo, Yingquan ^a   Ma, Ruoting ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Alpinetin; Cytokine; LPS; MAPK; NF B; PPAR ; TLR4

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ALPINETIN; ANTIINFLAMMATORY AGENT; FLAVONOID; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BETA ACTIN GENE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; ENZYME RELEASE; ENZYME REPRESSION; GENE; GENE EXPRESSION; HORMONAL REGULATION; HUMAN; HUMAN CELL; IL 1 BETA GENE; IL 6 GENE; MACROPHAGE; MEDIATOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TNF ALPHA GENE; WESTERN BLOTTING;

ALPINETIN; CYTOKINE; LPS; MAPK; NF-ΚB; PPAR-Γ; TLR4;

ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CYTOKINES; ENZYME ACTIVATION; FLAVANONES; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; LIPOPOLYSACCHARIDES; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PPAR GAMMA; TOLL-LIKE RECEPTOR 4;

EID: 84890124270     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.09.049     Document Type: Article

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