Milrinone-induced postconditioning reduces hepatic ischemia-reperfusion injury in rats: The roles of phosphatidylinositol 3-kinase and nitric oxide

Journal of Surgical Research

Volumn 186, Issue 1, 2014, Pages 446-451

  Toyoda, Tomomi ^a   Tosaka, Shinya ^a   Tosaka, Reiko ^a   Maekawa, Takuji ^a   Cho, Sungsam ^a   Eguchi, Susumu ^b   Nakashima, Masahiro ^b   Sumikawa, Koji ^c  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

^c Nagasakiken Saiseikai Hospital   (Japan)

Author keywords

Ischemia reperfusion injury; Liver; Milrinone; Nitric oxide synthase; Phosphatidylinositol 3 kinase

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASE; MILRINONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; HISTOPATHOLOGY; LIVER FUNCTION; LIVER ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ISCHEMIA-REPERFUSION INJURY; LIVER; MILRINONE; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3-KINASE;

ALANINE TRANSAMINASE; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ISCHEMIC POSTCONDITIONING; LIVER; MALE; MILRINONE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHODIESTERASE 3 INHIBITORS; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 84890118750     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.09.007     Document Type: Article

References (29)

1. F. Serracino-Inglott, N.A. Habib, and R.T. Mathie Hepatic ischemia-reperfusion injury Am J Surg 181 2001 160
2. R. Carini, and E. Albano Recent insights on the mechanisms of liver preconditioning Gastroenterology 125 2003 148
3. S. Yan, L.M. Jin, Y.X. Liu, L. Zhou, H.Y. Xie, and S.S. Zheng Outcomes and mechanisms of ischemic preconditioning in liver transplantation Hepatobiliary Pancreat Dis Int 9 2010 346
4. E. Alchera, C. Dal Ponte, C. Imarisio, E. Albano, and R. Carini Molecular mechanisms of liver preconditioning World J Gastroenterol 16 2010 6058
5. N. Wang, J.G. Lu, and X.L. He Effects of ischemic postconditioning on reperfusion injury in rat liver grafts after orthotopic liver transplantation Hepatol Res 39 2009 382
6. J.Y. Guo, T. Yang, and Sun Xg Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway J Biomed Sci 18 2011 79
7. H.C. Lin, T.K. Lee, C.C. Tsai, I.R. Lai, and K.S. Lu Ischemic postconditioning protects liver from ischemia-reperfusion injury by modulating mitochondrial permeability transition Transplantation 93 2012 265
8. C. Dal Ponte, E. Alchera, and A. Follenzi Pharmacological postconditioning protects against hepatic ischemia/reperfusion injury Liver Transpl 17 2011 474
9. H.M. Shawky, S.M. Younan, L.A. Rashed, and H. Shoukry Effect of recombinant erythropoietin on ischemia-reperfusion-induced apoptosis in rat liver J Physiol Biochem 68 2012 19
10. B. Beck-Schimmer, S. Breitenstein, and J.M. Bonvini Protection of pharmacological postconditioning in liver surgery: results of prospective randomized control trial Ann Surg 256 2012 837
11. M. Yano, M. Kohno, and T. Ohtuka Effect of milrinone on left ventricular relaxation and Ca(2+) uptake function of cardiac sarcoplasmic reticulum Am J Physiol 279 2000 H1898
12. J.Y. Niemann, D. Garner, E. Khaleeli, and R.J. Lewis Milrinone facilitates resuscitation from cardiac arrest and attenuate postresuscitation myocardial dysfunction Circulation 108 2003 3031
13. M. Jebeli, M. Ghazinoor, and M.H. Mandegar Effect of milrinone on short-term outcome of patients with myocardial dysfunction undergoing coronary artery bypass graft: a randomized controlled trial Cardiol J 17 2010 73
14. T. Ikegami, S. Nishizaki, R. Hiroshige, R. Ohta, K. Yanaga, and K. Sugimachi Experimental study of a type 3 phosphodiesterase inhibitor on liver graft function Br J Surg 88 2001 59
15. K. Satoh, M. Kume, and Y. Abe Implication of protein kinase A for a hepato-protective mechanism of milrinone pretreatment J Surg Res 155 2009 32
16. M.H. Huang, Y. Wu, and V. Nguyen Heart protection by combination therapy with esmolol and milrinone at late-ischemia and early reperfusion Cardiovasc Drugs Ther 25 2011 223
17. F. Gao, E. Gao, and T.L. Yue Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation Circulation 105 2002 1497
18. J. Li, H. Zhang, and F. Wu Insulin inhibits tumor necrosis factor-alpha induction in myocardial ischemia/reperfusion: role of Akt and endothelial nitric oxide synthase phosphorylation Crit Care Med 36 2008 1551
19. S. Suzuki, L.H. Toledo-Pereyra, F.J. Rodriguez, and D. Cejalvo Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury Transplantation 55 1993 1265
20. W.X. Zhang, W. Yin, and L. Zhang Preconditioning and postconditioning reduce hepatic ischemia-reperfusion injury in rats Hepatobiliary Pancreat Dis Int 8 2009 586
21. K. Izushi, A. Tsung, and M.A. Hossain Ischemic preconditioning of the murine liver protects through the Akt kinase pathway Hepatology 44 2006 573
22. Y. Guo, T. Yang, and J. Lu Rb1 postconditioning attenuates liver warm ischemia-reperfusion injury through ROS-NO-HIF pathway Life Sci 88 2011 598
23. M. Abu-Amara, S.Y. Yang, A. Seifalian, B. Davidson, and B. Fuller The nitric oxide pathway-evidence and mechanisms for protection against ischaemia reperfusion injury Liver Int 32 2012 531
24. E.E. Montalvo-Jave, T. Escalante-Tattersfield, J.A. Ortega-Salgado, E. Pina, and D.A. Geller Factors in the pathophysiology of the liver ischemia-reperfusion injury J Surg Res 147 2008 153
25. J.S. Kim, S. Ohshima, P. Pediaditakis, and J.J. Lemasters Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition Hepatology 39 2004 1533
26. S. Matsumoto, S. Cho, and S. Tosaka Hyperglycemia raises the threshold of levosimendan- but not milrinone-induced postconditioning in rat heart Cardiovasc Diabetol 11 2012 4
27. H. Kin, Z.Q. Zhao, and H.Y. Sun Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion Cardiovasc Res 62 2004 74
28. F. Roubille, A. Franck-Miclo, and A. Covinhes Delayed postconditioning in the mouse heart in vivo Circulation 124 2011 1330
29. T. Maekawa, S. Cho, and T. Ichinomiya Fasudil administered during early reperfusion protects against myocardial infarction through activation of PI3K/Akt/NOS pathway in rats Circ Cont 33 2012 96 Technology