Running on empty? the compensatory reserve index

Journal of Trauma and Acute Care Surgery

Volumn 75, Issue 6, 2013, Pages 1053-1059

  Moulton, Steven L ^a,b   Mulligan, Jane ^b   Grudic, Greg Z ^b   Convertino, Victor A ^c  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Flashback Technologies Inc   (United States)

^c US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Hypotension; Lower body negative pressure; Pulse oximetry

Indexed keywords

ALGORITHM; BLEEDING; BLOOD VOLUME; BRADYCARDIA; CLINICAL PROTOCOL; COMPENSATORY RESERVE INDEX; CONFERENCE PAPER; HEMODYNAMIC PARAMETERS; HUMAN; HYPOTENSION; HYPOVOLEMIA; LOWER BODY NEGATIVE PRESSURE; MACHINE LEARNING; MAJOR CLINICAL STUDY; MEDICAL DEVICE; NON INVASIVE PROCEDURE; PRIORITY JOURNAL; PULSE OXIMETER; PULSE OXIMETRY; SYSTOLIC BLOOD PRESSURE; VITAL SIGN;

ADOLESCENT; ADULT; BLOOD PRESSURE; BLOOD VOLUME; FEMALE; HEMORRHAGE; HUMANS; HYPOVOLEMIA; LOWER BODY NEGATIVE PRESSURE; MALE; MIDDLE AGED; MODELS, THEORETICAL; REFERENCE VALUES; YOUNG ADULT;

EID: 84890045095     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e3182aa811a     Document Type: Conference Paper

References (40)

1. Convertino VA, Cooke WH, Holcomb JB. Arterial pulse pressure and its association with reduced stroke volume during progressive central hypovolemia. J Trauma. 2006;61(3):629-634.
2. Convertino VA, Ryan KL, Rickards CA, Salinas J, McManus JG, Cooke WH, et al. Physiological and medical monitoring for en route care of combat casualties. J Trauma. 2008;64(4):S342-S353.
3. Convertino VA. Lower body negative pressure as a tool for research in aerospace medicine and military medicine. J Gravit Physiol. 2001;8:1-14.
4. Convertino VA. Gender differences in autonomic functions associated with blood pressure regulation. Am J Physiol. 1998;275:R1909-R1920.
5. Convertino VA, Moulton SL, Grudic GZ, Rickards C, Hinojosa-Laborde C, Gerhardt RT, et al. Use of advanced machine-learning techniques for noninvasive monitoring of hemorrhage. J Trauma. 2011;71:S25-S32.
6. Cooke WH., Ryan KL, Convertino VA. Lower body negative pressure as a model to study progression to acute hemorrhagic shock in humans. J Appl Physiol. 2004;96:1249-1261.
7. Ryan KL, Cooke WH, Rickards CA, Lurie KG, Convertino VA. Changes in pulse character and mental status are late responses to central hypovolemia. Prehosp Emerg Care. 2008;12:192-198.
8. Ryan KL, Rickards CA, Ludwig VA, Convertino VA. Tracking central hypovolemia with ECG in humans: cautions for the use of heart period variability in patient monitoring. Shock. 2010;33:583-589.
9. Cooke WH, Rickards CA, Ryan KL, Kuusela TA, Convertino VA. Muscle sympathetic nerve activity during intense lower body negative pressure to syncope in humans. J Physiol. 2009;587:4987-4999.
10. McManus JG, Convertino VA, Cooke WH, Ludwig DA, Holcomb JB. R-wave amplitude in lead II of an electrocardiogram correlates with central hypovolemia in humans. Acad Emerg Med. 2006;13:1003-1010.
11. Breiman L. Random forests. Mach Learn. 2001;45(1):5-23.
12. Schölkopf B, Smola A. Learning With Kernels. Cambridge, MA: MIT Press; 2002.
13. Strohmann T, Grudic G. A Formulation for Minimax Probability Machine Regression. Advances in Neural Information Processing Systems 15. Cambridge, MA: MIT Press; 2003:769-776.
14. Strohmann T, Belitski A, Grudic G, DeCoste D. Sparse Greedy Minimax Probability Machine Classification. Advances in Neural Information Processing Systems 16. Cambridge, MA. MIT Press; 2004.
15. Bohte S, Breitenbach M, Grudic G. Nonparametric Classification With Polynomial Mpmc Cascades. International Conference on Machine Learning (ICML). 2004. Available at: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1. 100.4479&rep=rep1&type=pdf.
16. Breitenbach M, Grudic G. Clustering Through Ranking on Manifolds. International Conference on Machine Learning (ICML). 2005. Available at: http://www.machinelearning.org/proceedings/icml2005/papers/010-Clustering- BreitenbachGrudic.pdf.
17. Hastie T, Tibshirani R, Friedman J. The Elements of Statistical Learning: Data Mining, Inference, and Prediction. Vol 2. Springer-Verlag; 2009. Available at: http://www-stat.stanford.edu/~tibs/ElemStatLearn/.
18. Grudic G, Lawrence PD. Is nonparametric learning practical in very high dimensional spaces? Fifteenth International Joint Conference on Artificial Intelligence (IJCAI-97). 1997;804-809.
19. Convertino VA, Rickards CA, Lurie KG, Ryan KL. Hyperventilation in response to reduction in central blood volume to near syncope. Aviat Space Environ Med. 2009;80:1012-1017.
20. Ward KR, Tiba MH, Ryan KL, Torres I, Rickards CA, Witten T, et al. Oxygen transport characteristics of a human model of progressive hemorrhage. Resuscitation. 2010;81:987-993.
21. Hannon JP. Hemorrhage and hemorrhagic shock in swine: a review. In: Swindle MM, ed. Swine as Models in Biomedical Research. Ames, IA: Iowa State University Press; 1992:197-245.
22. Schafer K, VanSickle C, Hinojosa-Laborde C, Convertino VA. Physiological mechanisms underlying the failure of the 'shock index' as a tool for accurate assessment of patient status during progressive simulated hemorrhage. J Trauma. 2013;75:S197-S202.
23. Brasel KJ, Guse C, Gentilello LM, et al. Heart rate: is it truly a vital sign? J Trauma. 2007;62:812-817.
24. Victorino GP, Battistella FD, Wisner DH. Does tachycardia correlate with hypotension after trauma? J Am Coll Surg. 2003;196:679-684.
25. Convertino VA, Grudic GZ, Mulligan J, Moulton S. Estimation of individual-specific progression to cardiovascular instability using arterial waveforms. J Appl Physiol. 2013 [Epub ahead of print].
26. Chen L, Reisner AT, Gribok A, Reifman J. Exploration of prehospital vital sign trends for the prediction of trauma outcomes. Prehosp Emerg Care. 2009;13(3):286-294.
27. Cooke WH, Salinas J, Convertino VA, Ludwig DA, Hinds D, Duke JH, Moore FA, Holcomb JB. Heart rate variability and its association with mortality in pre-hospital trauma patients. J Trauma. 2006;60:363-370.
28. McManus JG, Ryan KL, Morton MJ, Rickards CA, Cooke WH, Convertino VA. Limitations of end-tidal CO2 as an early indicator of central hypovolemia in humans. Prehosp Emerg Care. 2008;12:199-205.
29. Van Sickle C, Schafer K, Grudic GZ, Mulligan J, Moulton S, Convertino VA. Evidence for an improved 'shock index' for assessment of patient status during progressive simulated hemorrhage. Aviat Space Environ Med. 2013;84:907-912.
30. Soller BR, Soyemi OO, Yang Y, Ryan KL, Rickards CA, Walz JM, Heard SO, Convertino VA. Noninvasively measured muscle oxygen saturation is an early indicator of central hypovolemia in humans. J Appl Physiol. 2008; 104:475-481.
31. Convertino VA, Rickards CA, Ryan KL. Autonomic mechanisms associated with heart rate and vasoconstrictor reserves. Clin Auton Res. 2012; 22:123-130.
32. Rickards CA, Ryan KL, Cooke WH, Convertino VA. Tolerance to central hypovolemia: the influence of oscillations in arterial pressure and cerebral blood velocity. J Appl Physiol. 2011;111:1048-1058.
33. Fu Q, Witkowski S, Okazaki K, Levine BD Effects of gender and hypovolemia on sympathetic neural responses to orthostatic stress. Am J Physiol. 2005;289:R109-R116.
34. McGrath SP, Ryan KL, Wendelken SM, Rickards CA, Convertino VA. Pulse Oximeter Plethysmographic Waveform Changes in Awake, Spontaneously Breathing, Hypovolemic Volunteers. Anesthesia and analgesia. 2011;112:368-374.
35. Awad AA, Stout RG, Ghobashy M, Rezkanna HA, Silverman DG, Shelley KH. Analysis of the ear pulse oximeter waveform. J Clin Monit Comput. 2006;20(3):175-184.
36. Gesquiere MJ, Awad AA, Silverman DG, Stout RG, Jablonka DH, Silverman TJ, et al. Impact of withdrawal of 450 ml of blood on respirationinduced oscillations of the ear plethysmography waveform. J Clin Monit Comput. 2007;21:277-282.
37. Secher NH, Sander-Jensen K, Werner C, Warberg J, Bie P. Bradycardia during severe but reversible hypovolemic shock in man. Circ Shock. 1984; 14:267-274.
38. Graboys TB, Lille RD, Polansky BJ, Chobanian AV. Effects of lower body negative pressure on plasma catecholamine, plasma renin activity and vectorcardiogram. Aerospace Med. 1974;45:834-839.
39. Schadt JC, Ludbrook J. Hemodynamic and neurohumoral responses to acute hypovolemia in conscious mammals. Am J Physiol Heart Circ Physiol. 1991;260:H305-H318.
40. McManus JG, Yershov AL, Ludwig DA, Holcomb JB, Salinas J, Dubick MA, Convertino VA, Hinds D, David D, Flanagan T, et al. Radial pulse character relationships to systolic blood pressure and trauma outcomes. Prehosp Emerg Care. 2005;9:423-428.