Markers of endothelial dysfunction differ between subphenotypes in children with sickle cell disease

Thrombosis Research

Volumn 132, Issue 6, 2013, Pages 712-717

  Van Der Land, Veronica ^a   Peters, Marjolein ^a   Biemond, Bart J ^b   Heijboer, Harriët ^a   Harteveld, Cornelis L ^c   Fijnvandraat, Karin ^a  

^a EMMA CHILDREN S HOSPITAL   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Endothelial dysfunction; Pediatric hematology oncology; Sickle cell disease; von Willebrand factor; von Willebrand factor propeptide

Indexed keywords

HEMOGLOBIN BETA CHAIN; LACTATE DEHYDROGENASE; VON WILLEBRAND FACTOR;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHILDHOOD DISEASE; DISEASE ASSOCIATION; ENDOTHELIAL DYSFUNCTION; FEMALE; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REFERENCE VALUE; SCHOOL CHILD; SICKLE CELL ANEMIA;

CAR; CENTRAL AFRICAN REPUBLIC HAPLOTYPE; ELISA; ENDOTHELIAL DYSFUNCTION; ENZYME-LINKED IMMUNOSORBENT ASSAY; F1+2; HB; HBF; HED; HEMOGLOBIN; HEMOGLOBIN F PERCENTAGE; HEMOLYSIS-ENDOTHELIAL DYSFUNCTION SUBPHENOTYPE; LACTATE DEHYDROGENASE; LDH; MAGNETIC RESONANCE ANGIOGRAPHY; MAGNETIC RESONANCE IMAGING; MRA; MRI; NITRIC OXIDE; NO; PEDIATRIC HEMATOLOGY/ONCOLOGY; PROTHROMBIN FRAGMENT 1 AND 2; SCD; SCI; SICKLE CELL DISEASE; SILENT CEREBRAL INFARCTS; TAT; THROMBIN-ANTITHROMBIN COMPLEX; VISCOSITY-VASO-OCCLUSION SUBPHENOTYPE; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR PROPEPTIDE; VVO; VWF;

ADOLESCENT; ANEMIA, SICKLE CELL; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DISEASE PROGRESSION; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; PHENOTYPE; RISK ASSESSMENT; STROKE; VON WILLEBRAND FACTOR;

EID: 84889888935     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2013.10.006     Document Type: Article

References (24)

1. G.J. Kato, M.T. Gladwin, and M.H. Steinberg Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes Blood Rev 21 1 Jan 2007 37 47
2. G.J. Kato, V. McGowan, R.F. Machado, J.A. Little, J. Taylor, and C.R. Morris Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease Blood 107 6 Mar 15 2006 2279 2285
3. R.P. Hebbel Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine Am J Hematol 86 2 Feb 2011 123 154
4. D.C. Rees, T.N. Williams, and M.T. Gladwin Sickle-cell disease Lancet 376 9757 Dec 11 2010 2018 2031
5. D.C. Rees, and J.S. Gibson Biomarkers in sickle cell disease Br J Haematol 156 4 Feb 2012 433 445
6. J. Chen, W.E. Hobbs, J. Le, P.J. Lenting, P.G. de Groot, and J.A. Lopez The rate of hemolysis in sickle cell disease correlates with the quantity of active von Willebrand factor in the plasma Blood 117 13 Mar 31 2011 3680 3683
7. A.D. Blann, S. Marwah, G. Serjeant, D. Bareford, and J. Wright Platelet activation and endothelial cell dysfunction in sickle cell disease is unrelated to reduced antioxidant capacity Blood Coagul Fibrinolysis 14 3 Apr 2003 255 259
8. E. Nur, E.J. van Beers, S. Martina, I. Cuccovillo, H.M. Otten, and J.J. Schnog Plasma levels of pentraxin-3, an acute phase protein, are increased during sickle cell painful crisis Blood Cells Mol Dis 46 3 Mar 15 2011 189 194
9. J.S. Mohan, G.Y. Lip, J. Wright, D. Bareford, and A.D. Blann Plasma levels of tissue factor and soluble E-selectin in sickle cell disease: relationship to genotype and to inflammation Blood Coagul Fibrinolysis 16 3 Apr 2005 209 214
10. S. Krishnan, J. Siegel, G. Pullen Jr., M. Hevelow, C. Dampier, and M. Stuart Increased von Willebrand factor antigen and high molecular weight multimers in sickle cell disease associated with nocturnal hypoxemia Thromb Res 122 4 2008 455 458
11. A. Borchiellini, K. Fijnvandraat, J.W. ten Cate, D. Pajkrt, S.J. van Deventer, and G. Pasterkamp Quantitative analysis of von Willebrand factor propeptide release in vivo: effect of experimental endotoxemia and administration of 1-deamino-8-D-arginine vasopressin in humans Blood 88 8 Oct 15 1996 2951 2958
12. J.A. van Mourik, R. Boertjes, I.A. Huisveld, K. Fijnvandraat, D. Pajkrt, and P.J. van Genderen von Willebrand factor propeptide in vascular disorders: A tool to distinguish between acute and chronic endothelial cell perturbation Blood 94 1 Jul 1 1999 179 185
13. A. Verrotti, R. Greco, F. Basciani, G. Morgese, and F. Chiarelli von Willebrand factor and its propeptide in children with diabetes. Relation between endothelial dysfunction and microalbuminuria Pediatr Res 53 3 Mar 2003 382 386
14. J. Cejka Enzyme immunoassay for factor VIII-related antigen Clin Chem 28 6 Jun 1982 1356 1358
15. H. Pelzer, A. Schwarz, and W. Stuber Determination of human prothrombin activation fragment 1 + 2 in plasma with an antibody against a synthetic peptide Thromb Haemost 65 2 Feb 12 1991 153 159
16. J.A. Hoek, A. Sturk, J.W. ten Cate, R.J. Lamping, F. Berends, and J.J. Borm Laboratory and clinical evaluation of an assay of thrombin-antithrombin III complexes in plasma Clin Chem 34 10 Oct 1988 2058 2062
17. A.W. Al-Saqladi, B.J. Brabin, H.A. Bin-Gadeem, W.A. Kanhai, M. Phylipsen, and C.L. Harteveld Beta-globin gene cluster haplotypes in Yemeni children with sickle cell disease Acta Haematol 123 3 2010 182 185
18. M. Phylipsen, S. Yamsri, E.E. Treffers, D.T. Jansen, W.A. Kanhai, and E.M. Boon Non-invasive prenatal diagnosis of beta-thalassemia and sickle-cell disease using pyrophosphorolysis-activated polymerization and melting curve analysis Prenat Diagn 32 6 Jun 2012 578 587
19. T.M. Wick, J.L. Moake, M.M. Udden, S.G. Eskin, D.A. Sears, and L.V. McIntire Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow J Clin Invest 80 3 Sep 1987 905 910
20. U.M. Vischer, J.J. Emeis, H.J. Bilo, C.D. Stehouwer, C. Thomsen, and O. Rasmussen von Willebrand factor (vWf) as a plasma marker of endothelial activation in diabetes: improved reliability with parallel determination of the vWf propeptide (vWf:AgII) Thromb Haemost 80 6 Dec 1998 1002 1007
21. M.C. Trappenburg, M. van Schilfgaarde, F.C.P. Frerichs, H.M.H. Spronk, H. ten Cate, C.W.H. de Fijter, W.E. Terpstra, and A. Leyte Chronic renal failure is accompanied by endothelial activation and a large increase in microparticle numbers with reduced procoagulant capacity Nephrol Dial Transplant 27 4 Apr 2012 1446 1453
22. A.D. Blann, C. de Romeuf, C. Mazurier, and C.N. McCollum Circulating von Willebrand factor antigen II in atherosclerosis: a comparison with von Willebrand factor and soluble thrombomodulin Blood Coagul Fibrinolysis 9 3 Apr 1998 261 266
23. A.Y. Nossent, V. van Marion, N.H. van Tilburg, F.R. Rosendaal, R.M. Bertina, J.A. van Mourik, and H.J.C. Eikenboom von Willebrand factor and its propeptide: the influence of secretion and clearance on protein levels and the risk of venous thrombosis J Thromb Haemost 4 12 Dec 2006 2556 2562
24. M.J. Hollestelle, C.M. Loots, A. Squizzato, T. Renne, B.J. Bouma, and P.G. de Groot Decreased active von Willebrand factor level owing to shear stress in aortic stenosis patients J Thromb Haemost 9 5 May 2011 953 958