Chronic thromboembolic pulmonary hypertension-associated dysfibrinogenemias exhibit disorganized fibrin structure

Thrombosis Research

Volumn 132, Issue 6, 2013, Pages 729-734

  Marsh, James J ^a   Chiles, Peter G ^a   Liang, Ni Cheng ^a   Morris, Timothy A ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Confocal microscopy; Fibrinogen; Fibrinolysis; Pulmonary embolism; Thrombosis

Indexed keywords

FIBRIN; THROMBIN;

ARTICLE; BLOOD CLOT LYSIS; CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION; CONFOCAL LASER MICROSCOPY; DYSFIBRINOGENEMIA; FIBRINOLYTIC THERAPY; HUMAN; LUNG PERFUSION; POROSITY; PRIORITY JOURNAL; PROTEIN STRUCTURE; SCAR; TURBIDITY; VENOUS THROMBOEMBOLISM;

CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION; CHRONIC THROMBOTIC VENOUS DISEASE; CONFOCAL MICROSCOPY; CTEPH; CTVD; FIBRINOGEN; FIBRINOLYSIS; PULMONARY EMBOLISM; THROMBOSIS;

AFIBRINOGENEMIA; CASE-CONTROL STUDIES; COHORT STUDIES; FIBRIN; FIBRINOGEN; FIBRINOLYSIS; HUMANS; HYPERTENSION, PULMONARY; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; PROTEIN CONFORMATION; THROMBOSIS;

EID: 84889886716     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2013.09.024     Document Type: Article

References (42)

1. J.A. Paraskos, S.J. Adelstein, R.E. Smith, F.D. Rickman, W. Grossman, and L. Dexter Late prognosis of acute pulmonary embolism N Engl J Med 289 2 Jul 12 1973 55 58 [PubMed PMID: 4710405]
2. R.J. Hall, G.C. Sutton, and I.H. Kerr Long-term prognosis of treated acute massive pulmonary embolism Br Heart J 39 10 Oct 1977 1128 1134 [PubMed PMID: 911565]
3. G.C. Sutton, R.J. Hall, and I.H. Kerr Clinical course and late prognosis of treated subacute massive, acute minor, and chronic pulmonary thromboembolism Br Heart J 39 10 Oct 1977 1135 1142 [PubMed PMID: 911566]
4. N.D. De Soyza, and M.L. Murphy Persistent post-embolic pulmonary hypertension Chest 62 6 Dec 1972 665 668 [PubMed PMID: 4635413]
5. D. Phear Pulmonary embolism. A study of late prognosis Lancet 2 Oct 15 1960 832 835 [PubMed PMID: 13735229]
6. R. Prediletto, P. Paoletti, E. Fornai, A. Perissinotto, S. Petruzzelli, and B. Formichi Natural course of treated pulmonary embolism. Evaluation by perfusion lung scintigraphy, gas exchange, and chest roentgenogram Chest 97 3 Mar 1990 554 561
7. P. Fedullo, K.M. Kerr, N.H. Kim, and W.R. Auger Chronic thromboembolic pulmonary hypertension Am J Respir Crit Care Med 183 12 Jun 15 2011 1605 1613 [PubMed PMID: 21330453. Epub 2011/02/19. eng]
8. P. Prandoni, A.W. Lensing, M.H. Prins, E. Bernardi, A. Marchiori, and P. Bagatella Residual venous thrombosis as a predictive factor of recurrent venous thromboembolism Ann Intern Med 137 12 Dec 17 2002 955 960 [PubMed PMID: 12484710]
9. S.R. Kahn, I. Shrier, J.A. Julian, T. Ducruet, L. Arsenault, and M.J. Miron Determinants and time course of the postthrombotic syndrome after acute deep venous thrombosis Ann Intern Med 149 10 Nov 18 2008 698 707 [PubMed PMID: 19017588. Epub 2008/11/20. eng]
10. J.W. Weisel Structure of fibrin: impact on clot stability J Thromb Haemost 5 Suppl. 1 Jul 2007 116 124 [PubMed PMID: 17635717. Epub 2007/08/01. eng]
11. T.A. Morris, J.J. Marsh, P.G. Chiles, M.M. Magana, N.C. Liang, and X. Soler High prevalence of dysfibrinogenemia among patients with chronic thromboembolic pulmonary hypertension Blood 114 9 Aug 27 2009 1929 1936 [PubMed PMID: 19420351. Pubmed Central PMCID: 2738577. Epub 2009/05/08. eng]
12. T.A. Morris, J.J. Marsh, P.G. Chiles, W.R. Auger, P.F. Fedullo, and V.L. Woods Jr. Fibrin derived from patients with chronic thromboembolic pulmonary hypertension is resistant to lysis Am J Respir Crit Care Med 173 11 Jun 1 2006 1270 1275 [PubMed PMID: 16514114. Pubmed Central PMCID: 2662971. eng]
13. J. Collet, J. Soria, M. Mirshahi, M. Hirsch, F.B. Dagonnet, and J. Caen Dusart syndrome: A new concept of the relationship between fibrin clot architecture and fibrin clot degradability: Hypofibrinolysis related to an abnormal clot structure Blood 82 8 1993 2462 2469
14. T.J. Podor, S. Campbell, P. Chindemi, D.M. Foulon, D.H. Farrell, and P.D. Walton Incorporation of vitronectin into fibrin clots. Evidence for a binding interaction between vitronectin and gamma A/gamma' fibrinogen J Biol Chem 277 9 Mar 1 2002 7520 7528 [PubMed PMID: 11744726]
15. D.V. Sakharov, J.F. Nagelkerke, and D.C. Rijken Rearrangements of the fibrin network and spatial distribution of fibrinolytic components during plasma clot lysis. Study with confocal microscopy J Biol Chem 271 4 Jan 26 1996 2133 2138 [PubMed PMID: 8567670]
16. R.F. Doolittle, and L. Pandi Binding of synthetic B knobs to fibrinogen changes the character of fibrin and inhibits its ability to activate tissue plasminogen activator and its destruction by plasmin Biochemistry 45 8 Feb 28 2006 2657 2667 [PubMed PMID: 16489759. eng]
17. T.A. Morris, M.M. Magana, J.J. Marsh, P.G. Chiles, D.J. DeSantis, and R.A. Gruppo Heterozygous Fibrinogen γ-375 Arg-Trp Mutation Associated With Excessive Sialylation, Plasmin Resistance and Chronic Thromboembolic Pulmonary Hypertension J Thromb Haemost 5 Supplement 2 2007 P-W-388 [Pubmed Central PMCID: (none: abstract)]
18. S.O. Brennan, G. Maghzal, B.L. Shneider, R. Gordon, M.S. Magid, and P.M. George Novel fibrinogen gamma375 Arg- > Trp mutation (fibrinogen aguadilla) causes hepatic endoplasmic reticulum storage and hypofibrinogenemia Hepatology 36 3 Sep 2002 652 658 [PubMed PMID: 12198657. eng]
19. R.F. Doolittle Determining the crystal structure of fibrinogen J Thromb Haemost 2 5 May 2004 683 689 [PubMed PMID: 15099268]
20. B. Blomback, K. Carlsson, B. Hessel, A. Liljeborg, R. Procyk, and N. Aslund Native fibrin gel networks observed by 3D microscopy, permeation and turbidity Biochim Biophys Acta 997 1-2 Jul 27 1989 96 110 [PubMed PMID: 2752057. eng]
21. D.A. Gabriel, K. Muga, and E.M. Boothroyd The effect of fibrin structure on fibrinolysis J Biol Chem 267 34 Dec 5 1992 24259 24263 [PubMed PMID: 1447176. Epub 1992/12/05. eng]
22. M.E. Carr Jr., and B.M. Alving Effect of fibrin structure on plasmin-mediated dissolution of plasma clots Blood Coagul Fibrinolysis 6 6 Sep 1995 567 573 [PubMed PMID: 7578900]
23. J.L. Mullin, S.E. Norfolk, J.W. Weisel, and S.T. Lord Clot lysis of variant recombinant fibrinogens confirms that fiber diameter is a major determinant of lysis rate Ann N Y Acad Sci 936 2001 331 334 [PubMed PMID: 11460489. eng]
24. R. Procyk, B. Kudryk, S. Callender, and B. Blomback Accessibility of epitopes on fibrin clots and fibrinogen gels Blood 77 7 Apr 1 1991 1469 1475 [PubMed PMID: 1706954. eng]
25. A. Bini, S. Callender, R. Procyk, B. Blomback, and B.J. Kudryk Flow and Antibody Binding Properties of Hydrated Fibrins Prepared From Plasma, Platelet Rich Plasma and Whole Blood Thromb Res 76 2 1994 145 156
26. J. Qi, and D.L. Kreutzer Fibrin activation of vascular endothelial cells. Induction of IL-8 expression J Immunol 155 2 7/15/1995 867 876 [JID - 2985117R]
27. J. Martinez, A. Ferber, T.L. Bach, and C.H. Yaen Interaction of fibrin with VE-cadherin Ann N Y Acad Sci 936 2001 386 405 [PubMed PMID: 3156856]
28. N.L. Tsakadze, Z. Zhao, and S.E. D'Souza Interactions of intercellular adhesion molecule-1 with fibrinogen Trends Cardiovasc Med 12 3 Apr 2002 101 108 [PubMed PMID: 12007734]
29. J.W. Barnard, M.G. Biro, S.K. Lo, S. Ohno, M.A. Carozza, and M. Moyle Neutrophil inhibitory factor prevents neutrophil-dependent lung injury J Immunol 155 10 Nov 15 1995 4876 4881 [PubMed PMID: 7594491]
30. L.A. Bunce, L.A. Sporn, and C.W. Francis Endothelial cell spreading on fibrin requires fibrinopeptide B cleavage and amino acid residues 15-42 of the beta chain J Clin Invest 89 3 3/1992 842 850 [JID - 7802877]
31. K.F. Standeven, P.J. Grant, A.M. Carter, T. Scheiner, J.W. Weisel, and R.A. Ariens Functional analysis of the fibrinogen Aalpha Thr312Ala polymorphism: effects on fibrin structure and function Circulation 107 18 May 13 2003 2326 2330 [PubMed PMID: 12707238. Epub 2003/04/23. eng]
32. R. Ajjan, B.C. Lim, K.F. Standeven, R. Harrand, S. Dolling, and F. Phoenix Common variation in the C-terminal region of the fibrinogen beta-chain: effects on fibrin structure, fibrinolysis and clot rigidity Blood 111 2 Jan 15 2008 643 650 [PubMed PMID: 17925485. Epub 2007/10/11. eng]
33. G.J. Maghzal, S.O. Brennan, and P.M. George Fibrinogen B beta polymorphisms do not directly contribute to an altered in vitro clot structure in humans Thromb Haemost 90 6 Dec 2003 1021 1028 [PubMed PMID: 14652632. Epub 2003/12/04. eng]
34. V. Pengo, A.W. Lensing, M.H. Prins, A. Marchiori, B.L. Davidson, and F. Tiozzo Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism N Engl J Med 350 22 May 27 2004 2257 2264 [PubMed PMID: 15163775]
35. A. Ribeiro, P. Lindmarker, H. Johnsson, A. Juhlin-Dannfelt, and L. Jorfeldt Pulmonary embolism: one-year follow-up with echocardiography doppler and five-year survival analysis Circulation 99 10 Mar 16 1999 1325 1330 [PubMed PMID: 10077516]
36. S.R. Kahn, and J.S. Ginsberg Relationship between deep venous thrombosis and the postthrombotic syndrome Arch Intern Med 164 1 Jan 12 2004 17 26 [PubMed PMID: 14718318. eng]
37. P. Wille-Jorgensen, T. Jorgensen, M. Andersen, and M. Kirchhoff Postphlebitic syndrome and general surgery: an epidemiologic investigation Angiology 42 5 May 1991 397 403 [PubMed PMID: 2035891. eng]
38. E. Biguzzi, E. Mozzi, A. Alatri, E. Taioli, M. Moia, and P.M. Mannucci The post-thrombotic syndrome in young women: retrospective evaluation of prognostic factors Thromb Haemost 80 4 Oct 1998 575 577 [PubMed PMID: 9798972. eng]
39. D. Bonderman, J. Jakowitsch, C. Adlbrecht, M. Schemper, P.A. Kyrle, and V. Schonauer Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension Thromb Haemost 93 3 Mar 2005 512 516 [PubMed PMID: 15735803. eng]
40. G.J. Maghzal, S.O. Brennan, and P.M. George The sialic acid content of fibrinogen decreases during pregnancy and increases in response to fibrate therapy Thromb Res 115 4 2005 293 299 [PubMed PMID: 15668189. Epub 2005/01/26. eng]
41. A. Squizzato, M. Galli, E. Romualdi, F. Dentali, P.W. Kamphuisen, and L. Guasti Statins, fibrates, and venous thromboembolism: a meta-analysis Eur Heart J 31 10 May 2010 1248 1256 [PubMed PMID: 20031958. Epub 2009/12/25. eng]
42. J.M. Kollman, L. Pandi, M.R. Sawaya, M. Riley, and R.F. Doolittle Crystal structure of human fibrinogen Biochemistry 48 18 May 12 2009 3877 3886 [PubMed PMID: 19296670. Epub 2009/03/20. eng]