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Volumn 13, Issue 6, 2013, Pages 623-629

Subcutaneous immunoglobulin replacement therapy: The European experience

Author keywords

Immunoglobulin; Patient education; Primary immune deficiency; Self infusion; Subcutaneous

Indexed keywords

HUMAN IMMUNOGLOBULIN; IMMUNOGLOBULIN;

EID: 84889878773     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0000000000000013     Document Type: Review
Times cited : (23)

References (39)
  • 1
    • 0000419304 scopus 로고
    • Agammaglobulinaemia
    • Bruton OC. Agammaglobulinaemia. Pediatrics 1952; 9:722-728.
    • (1952) Pediatrics , vol.9 , pp. 722-728
    • Bruton, O.C.1
  • 2
    • 0014755371 scopus 로고
    • Primary immunodeficiency syndromes
    • Asherson GL, Hill KE, Citron KM. Primary immunodeficiency syndromes. Thorax 1970; 25:254-255.
    • (1970) Thorax , vol.25 , pp. 254-255
    • Asherson, G.L.1    Hill, K.E.2    Citron, K.M.3
  • 3
    • 0021071220 scopus 로고
    • Treatment of antibody deficiency syndromes with subcutaneous infusion of gamma globulin
    • Roord J, van der Meer JW, Kuis W, van Furth R. Treatment of antibody deficiency syndromes with subcutaneous infusion of gamma globulin. Birth Defects Orig Artic Ser 1983; 19:217-221.
    • (1983) Birth Defects Orig Artic Ser , vol.19 , pp. 217-221
    • Roord, J.1    Van Der Meer, J.W.2    Kuis, W.3    Van Furth, R.4
  • 4
    • 77956190931 scopus 로고    scopus 로고
    • Immunomodulatory therapy to achieve maximum efficacy: Doses, monitoring, compliance, and self-infusion at home
    • Lucas M, Hugh-Jones K, Welby A, et al. Immunomodulatory therapy to achieve maximum efficacy: doses, monitoring, compliance, and self-infusion at home. J Clin Immunol 2010; 30 (Suppl. 1):S84-S89.
    • (2010) J Clin Immunol , vol.30 , Issue.SUPPL. 1
    • Lucas, M.1    Hugh-Jones, K.2    Welby, A.3
  • 5
    • 0001708115 scopus 로고
    • Chemical, clinical and immunological studies on the products of human plasma fractionation. 1. The characterisation of the protein fractions of human plasma
    • Cohn E, Oncleym JL, Strong LE, et al. Chemical, clinical and immunological studies on the products of human plasma fractionation. 1. The characterisation of the protein fractions of human plasma. J Clin Invest 1944; 23:417-432.
    • (1944) J Clin Invest , vol.23 , pp. 417-432
    • Cohn, E.1    Oncleym, J.L.2    Strong, L.E.3
  • 6
    • 0025738608 scopus 로고
    • Home treatment of hypogammaglobulinaemia with scig by rapid infusion
    • Gardulf A, Hammarstrom L, Smith E. Home treatment of hypogammaglobulinaemia with SCIg by rapid infusion. Lancet 1991; 338:162-166.
    • (1991) Lancet , vol.338 , pp. 162-166
    • Gardulf, A.1    Hammarstrom, L.2    Smith, E.3
  • 7
    • 0028857579 scopus 로고
    • Subcutaneous immunoglobulin replacement in patients with primary antibody deficiencies: Safety and costs
    • Gardulf A, Andersen V, Bjorkander J, et al. Subcutaneous immunoglobulin replacement in patients with primary antibody deficiencies: safety and costs. Lancet 1995; 345:365-369.
    • (1995) Lancet , vol.345 , pp. 365-369
    • Gardulf, A.1    Andersen, V.2    Bjorkander, J.3
  • 8
    • 34548665264 scopus 로고    scopus 로고
    • Safety and efficacy of subcutaneous human immunoglobulin in children with primary immunodeficiencies
    • It is imortant to know that SCIg is well tolerated and accetable in children
    • Fasth A, Nystrom J. Safety and efficacy of subcutaneous human immunoglobulin in children with primary immunodeficiencies. Acta Paediatr Jpn 2007; 96:1474-1478. It is important to know that SCIg is well tolerated and acceptable in children.
    • (2007) Acta Paediatr Jpn , vol.96 , pp. 1474-1478
    • Fasth, A.1    Nystrom, J.2
  • 9
    • 33750842089 scopus 로고    scopus 로고
    • Replacement igg therapy and self therapy at home improve the health-related quality of life in patients with primary antibody deficiencies
    • The quality-of-life data are imortant for convincing healthcare roviders to suort immunoglobulin relacement theraies
    • Gardulf A, Nicolay U. Replacement IgG therapy and self therapy at home improve the health-related quality of life in patients with primary antibody deficiencies. Curr Opin Allergy Clin Immunol 2006; 6:434-442. The quality-of-life data are important for convincing healthcare providers to support immunoglobulin replacement therapies.
    • (2006) Curr Opin Allergy Clin Immunol , vol.6 , pp. 434-442
    • Gardulf, A.1    Nicolay, U.2
  • 10
    • 0029303667 scopus 로고
    • Lifelong treatment with gammaglobulin for primary antibody deficiencies: The patients' experiences of subcutaneous self-infusions and home therapy
    • Gardulf A, Bjo rvell H, Andersen V, et al. Lifelong treatment with gammaglobulin for primary antibody deficiencies: the patients' experiences of subcutaneous self-infusions and home therapy. J Adv Nurs 1995; 21:917-927.
    • (1995) J Adv Nurs , vol.21 , pp. 917-927
    • Gardulf, A.1    Bjorvell, H.2    Andersen, V.3
  • 11
    • 0031802363 scopus 로고    scopus 로고
    • Induction of unresponsiveness against iga in iga-deficient patients on subcutaneous immunoglobulin infusion therapy
    • Sundin U, Nava S, Hammarstrom L. Induction of unresponsiveness against IgA in IgA-deficient patients on subcutaneous immunoglobulin infusion therapy. Clin Exp Immunol 1998; 112:341-346.
    • (1998) Clin Exp Immunol , vol.112 , pp. 341-346
    • Sundin, U.1    Nava, S.2    Hammarstrom, L.3
  • 12
    • 0026089717 scopus 로고
    • Prophylactic effect of selfadministered pump-driven subcutaneous igg infusion in patients with antibody deficiency: A triple-blind cross-over study comparing p-igg levels of 3 g l-1 versus 6 g l-1
    • Remvig L, Andersen V, Hansen NE, Karle H. Prophylactic effect of selfadministered pump-driven subcutaneous IgG infusion in patients with antibody deficiency: A triple-blind cross-over study comparing P-IgG levels of 3 g l-1 versus 6 g l-1. J Intern Med 1991; 229:73-77.
    • (1991) J Intern Med , vol.229 , pp. 73-77
    • Remvig, L.1    Andersen, V.2    Hansen, N.E.3    Karle, H.4
  • 13
    • 0027438975 scopus 로고
    • Rapid subcutaneous immunoglobulin infusions in children
    • Thomas M, Brennan VM, Chapel H. Rapid subcutaneous immunoglobulin infusions in children. Lancet 1993; 342:1432-1433.
    • (1993) Lancet , vol.342 , pp. 1432-1433
    • Thomas, M.1    Brennan, V.M.2    Chapel, H.3
  • 14
    • 0031871760 scopus 로고    scopus 로고
    • Immunoglobulin replacement treatment by rapid subcutaneous infusion
    • Gaspar J, Gerritsen B, Jones A. Immunoglobulin replacement treatment by rapid subcutaneous infusion. Arch Dis Child 1998; 79:48-51.
    • (1998) Arch Dis Child , vol.79 , pp. 48-51
    • Gaspar, J.1    Gerritsen, B.2    Jones, A.3
  • 15
    • 0028173922 scopus 로고
    • Bioavailability of gammaglobulin after subcutaneous infusions in patients with common variable immunodeficiency
    • This study is ertinent to the harmacokinetic studies required by the most regulators and licensing authorities
    • Waniewski J, Gardulf A, Hammarstrom L. Bioavailability of gammaglobulin after subcutaneous infusions in patients with common variable immunodeficiency. J Clin Immunol 1994; 14:90-97. This study is pertinent to the pharmacokinetic studies required by the most regulators and licensing authorities.
    • (1994) J Clin Immunol , vol.14 , pp. 90-97
    • Waniewski, J.1    Gardulf, A.2    Hammarstrom, L.3
  • 16
    • 0036751568 scopus 로고    scopus 로고
    • Express subcutaneous igg infusions: Decreased time of delivery with maintained safety
    • Good data for convincing atients that seedy infusions are well tolerated
    • Hansen S, Gustafson R, Smith CI, Gardulf A. Express subcutaneous IgG infusions: decreased time of delivery with maintained safety. Clin Immunol 2002; 104:237-241. Good data for convincing patients that speedy infusions are well tolerated.
    • (2002) Clin Immunol , vol.104 , pp. 237-241
    • Hansen, S.1    Gustafson, R.2    Smith, C.I.3    Gardulf, A.4
  • 17
    • 0027180544 scopus 로고
    • The life situations of patients with primary antibody deficiency untreated or treated with subcutaneous gammaglobulin infusions
    • Gardulf A, Bjo rvell H, Gustafson R, et al. The life situations of patients with primary antibody deficiency untreated or treated with subcutaneous gammaglobulin infusions. Clin Exp Immunol 1993; 92:200-204.
    • (1993) Clin Exp Immunol , vol.92 , pp. 200-204
    • Gardulf, A.1    Bjorvell, H.2    Gustafson, R.3
  • 18
    • 4944262622 scopus 로고    scopus 로고
    • Children and adults with primary antibody deficiencies gain quality of life by subcutaneous igg self-infusions at home
    • Gardulf A, Nicolay U, Math D, et al. Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home. J Allergy Clin Immunol 2004; 114:936-942.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 936-942
    • Gardulf, A.1    Nicolay, U.2    Math, D.3
  • 19
    • 0035049375 scopus 로고    scopus 로고
    • Rapid subcutaneous igg replacement therapy at home for pregnant immunodeficient women
    • Gardulf A, Andersson E, Lindqvist M, et al. Rapid subcutaneous IgG replacement therapy at home for pregnant immunodeficient women. J Clin Immunol 2001; 21:150-154.
    • (2001) J Clin Immunol , vol.21 , pp. 150-154
    • Gardulf, A.1    Andersson, E.2    Lindqvist, M.3
  • 20
    • 0034073949 scopus 로고    scopus 로고
    • The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy
    • The first comparitive trial: important for European Medicines agency decision on equivalence of doses
    • Chapel H, Spickett GP, Ericson D, et al. The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy. J Clin Immunol 2000; 2:94-100. The first comparitive trial: important for European Medicines agency decision on equivalence of doses.
    • (2000) J Clin Immunol , vol.2 , pp. 94-100
    • Chapel, H.1    Spickett, G.P.2    Ericson, D.3
  • 21
    • 80255138611 scopus 로고    scopus 로고
    • Efficacy and safety of subcutaneous vivaglobin replacement therapy in previously untreated patients with primary immunodeficiency: A prospective, multicenter study
    • SCIg can be used in previously untreated patients
    • Borte M, Quinti I, Soresina A, et al. Efficacy and safety of subcutaneous vivaglobin replacement therapy in previously untreated patients with primary immunodeficiency: A prospective, multicenter study. J Clin Immunol 2011; 31:952-961. SCIg can be used in previously untreated patients.
    • (2011) J Clin Immunol , vol.31 , pp. 952-961
    • Borte, M.1    Quinti, I.2    Soresina, A.3
  • 22
    • 42049112189 scopus 로고    scopus 로고
    • Rapid subcutaneous immunoglobulin administration every second week results in high and stable serum immunoglobulin g levels in patients with primary antibody deficiencies
    • This study confirms the equivalence data for dosing and demonstrates the various pharmacokinetic measurements available
    • Gustafson R, Gardulf A, Hansen S, et al. Rapid subcutaneous immunoglobulin administration every second week results in high and stable serum immunoglobulin G levels in patients with primary antibody deficiencies. Clin Exp Immunol 2008; 152:274-279. This study confirms the equivalence data for dosing and demonstrates the various pharmacokinetic measurements available.
    • (2008) Clin Exp Immunol , vol.152 , pp. 274-279
    • Gustafson, R.1    Gardulf, A.2    Hansen, S.3
  • 23
    • 77952741985 scopus 로고    scopus 로고
    • Infection outcomes in patients with common variable immunodeficiency disorders: Relationship to immunoglobulin therapy over 22 years
    • This study demonstrates the importance of individual IgG trough levels in infection prevention
    • Lucas M, Lee M, Lortan J, et al. Infection outcomes in patients with common variable immunodeficiency disorders: relationship to immunoglobulin therapy over 22 years. J Allergy Clin Immunol 2010; 125:1354-1360. This study demonstrates the importance of individual IgG trough levels in infection prevention.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1354-1360
    • Lucas, M.1    Lee, M.2    Lortan, J.3
  • 24
    • 34547905737 scopus 로고    scopus 로고
    • Recognition, clinical diagnosis and management of patients with primary antibody defciencies: A systematic review
    • Wood P, Stanworth S, Burton J, et al. Recognition, clinical diagnosis and management of patients with primary antibody defciencies: A systematic review. Clin Exp Immunol 2007; 149:410-423.
    • (2007) Clin Exp Immunol , vol.149 , pp. 410-423
    • Wood, P.1    Stanworth, S.2    Burton, J.3
  • 25
    • 71149102844 scopus 로고    scopus 로고
    • Guidelines for the use of ivig for primary immune deficiency and solid organ transplantation
    • Nahirniak S, Hume H. Guidelines for the use of IVIG for primary immune deficiency and solid organ transplantation. Transfus Med Rev 2010; 24 (Suppl. 1).
    • Transfus Med Rev , vol.2010 , Issue.SUPPL. 1 , pp. 24
    • Nahirniak, S.1    Hume, H.2
  • 27
    • 84875701053 scopus 로고    scopus 로고
    • Controversies in igg replacement therapy in patients with antibody deficiency diseases
    • Gelfand E, Ochs HD, Shearer WT. Controversies in IgG replacement therapy in patients with antibody deficiency diseases. J Allergy Clin Immunol 2013; 131:1001-1005.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 1001-1005
    • Gelfand, E.1    Ochs, H.D.2    Shearer, W.T.3
  • 28
    • 0020076095 scopus 로고
    • Subcutaneous infusion of gammaglobulins in management of agammaglobulinaemia
    • Ugazio A, Duse M, Re R, et al. Subcutaneous infusion of gammaglobulins in management of agammaglobulinaemia. Lancet 1982; 319:226.
    • (1982) Lancet , vol.319 , pp. 226
    • Ugazio, A.1    Duse, M.2    Re, R.3
  • 29
    • 33745145825 scopus 로고    scopus 로고
    • Safety and efficacy of selfadministered subcutaneous immunoglobulin in patients with primary immunodeficiency disease
    • Ochs H, Gupta S, Kiessling P, et al. Safety and efficacy of selfadministered subcutaneous immunoglobulin in patients with primary immunodeficiency disease. J Clin Immunol 2006; 26:265-273.
    • (2006) J Clin Immunol , vol.26 , pp. 265-273
    • Ochs, H.1    Gupta, S.2    Kiessling, P.3
  • 30
    • 0023628406 scopus 로고
    • Self-infusion of intravenous immunoglobulin by immunodeficient patients at home
    • The first ublication of self-infusion of immunoglobulin in relacement theray
    • Ochs H, Lee ML, Fischer SH, et al. Self-infusion of intravenous immunoglobulin by immunodeficient patients at home. J Infect Dis 1987; 56:652-654. The first publication of self-infusion of immunoglobulin in replacement therapy.
    • (1987) J Infect Dis , vol.56 , pp. 652-654
    • Ochs, H.1    Lee, M.L.2    Fischer, S.H.3
  • 31
    • 0023735488 scopus 로고
    • Immunoglobulin replacement therapy by self-infusion at home
    • Chapel HBV, Delson E. Immunoglobulin replacement therapy by self-infusion at home. Clin Exp Immunol 1988; 73:160-162.
    • (1988) Clin Exp Immunol , vol.73 , pp. 160-162
    • Chapel, H.B.V.1    Delson, E.2
  • 32
    • 0042667057 scopus 로고    scopus 로고
    • Prospective audit of adverse reactions occurring in 459 pad patients receiving ivig
    • This study confirms the safety of self-infusion of therapeutic immunoglobulin in primary antibody deficiency patients
    • Brennan VM, Salomé -Bentley NJ, Chapel HM. Prospective audit of adverse reactions occurring in 459 PAD patients receiving IVIg. Clin Exp Immunol 2003; 133:247-251. This study confirms the safety of self-infusion of therapeutic immunoglobulin in primary antibody deficiency patients.
    • (2003) Clin Exp Immunol , vol.133 , pp. 247-251
    • Brennan, V.M.1    Salomé-Bentley, N.J.2    Chapel, H.M.3
  • 33
    • 72149122096 scopus 로고    scopus 로고
    • Subcutaneous immunoglobulin: Opportunities and outlook
    • Misbah S, Sturzenegger MH, Borte M, et al. Subcutaneous immunoglobulin: opportunities and outlook. Clin Exp Immunol 2009; 158 (Suppl. 1):51-59.
    • (2009) Clin Exp Immunol , vol.158 , Issue.SUPPL. 1 , pp. 51-59
    • Misbah, S.1    Sturzenegger, M.H.2    Borte, M.3
  • 34
    • 84872651749 scopus 로고    scopus 로고
    • Subcutaneous immunoglobulin: Rapid push vs. Infusion pump in pediatrics
    • The first ublication to indicate that no secial equiment is needed so imortant for cost-effectiveness
    • Shapiro R. Subcutaneous immunoglobulin: rapid push vs. infusion pump in pediatrics. Pediatr Allergy Immunol 2013; 24:49-53. The first publication to indicate that no special equipment is needed, so important for cost-effectiveness.
    • (2013) Pediatr Allergy Immunol , vol.24 , pp. 49-53
    • Shapiro, R.1
  • 35
    • 84872681374 scopus 로고    scopus 로고
    • Economic benefits of subcutaneous rapid push versus intravenous immunoglobulin infusion therapy in adult patients with primary immune deficiency
    • Confirmation of reduced costs: important for healthcare providers
    • Martin A, Lavoie L, Goetghebeur M, Schellenberg R. Economic benefits of subcutaneous rapid push versus intravenous immunoglobulin infusion therapy in adult patients with primary immune deficiency. Transfus Med 2013; 23:55-60.Confirmation of reduced costs: important for healthcare providers.
    • (2013) Transfus Med , vol.23 , pp. 55-60
    • Martin, A.1    Lavoie, L.2    Goetghebeur, M.3    Schellenberg, R.4
  • 36
    • 0029680562 scopus 로고    scopus 로고
    • Organizing care for patients with chronic illness
    • Wagner E, Austin B, von Korff M. Organizing care for patients with chronic illness. Milbank Q 1996; 74:511-543.
    • (1996) Milbank Q , vol.74 , pp. 511-543
    • Wagner, E.1    Austin, B.2    Von Korff, M.3
  • 37
    • 85013590598 scopus 로고    scopus 로고
    • The role of the nurses in recognizing and caring for patients with primary immunodeficiencies
    • Vickers P, Gardulf A, Warner A. The role of the nurses in recognizing and caring for patients with primary immunodeficiencies. Pharm Policy Law 2008; 10:43-50.
    • (2008) Pharm Policy Law , vol.10 , pp. 43-50
    • Vickers, P.1    Gardulf, A.2    Warner, A.3
  • 38
    • 46749117598 scopus 로고    scopus 로고
    • Quality of life and health-care resource utilization among children with primary immunodeficiency receiving home treatment with subcutaneous human immunoglobulin
    • Fasth A, Nystrom J. Quality of life and health-care resource utilization among children with primary immunodeficiency receiving home treatment with subcutaneous human immunoglobulin. J Clin Immunol 2008; 28:370-378.
    • (2008) J Clin Immunol , vol.28 , pp. 370-378
    • Fasth, A.1    Nystrom, J.2
  • 39
    • 0023735488 scopus 로고
    • Immunoglobulin replacement therapy by selfinfusion at home
    • Chapel H, Brennan V, Delson E. Immunoglobulin replacement therapy by selfinfusion at home. Clin Exp Immunol 1988; 73:160-162.
    • (1988) Clin Exp Immunol , vol.73 , pp. 160-162
    • Chapel, H.1    Brennan, V.2    Delson, E.3


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