Economic benefits of subcutaneous rapid push versus intravenous immunoglobulin infusion therapy in adult patients with primary immune deficiency

Transfusion Medicine

Volumn 23, Issue 1, 2013, Pages 55-60

  Martin, A ^a   Lavoie, L ^b   Goetghebeur, M ^b   Schellenberg, R ^a,c  

^a ST PAUL S HOSPITAL   (Canada)

^b LA SER Analytics   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Budget impact model; Cost minimisation; IVIG; Primary immune deficiencies; SCIG

Indexed keywords

IMMUNOGLOBULIN;

ARTICLE; CANADA; DRUG COST; DRUG INFUSION; ECONOMIC ASPECT; HEALTH CARE SYSTEM; HOSPITAL PERSONNEL; HUMAN; IMMUNE DEFICIENCY; IMMUNOTHERAPY; MAJOR CLINICAL STUDY; SENSITIVITY ANALYSIS;

ADULT; BRITISH COLUMBIA; BUDGETS; COST SAVINGS; HEALTH EXPENDITURES; HOME CARE SERVICES, HOSPITAL-BASED; HOSPITAL COSTS; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFUSIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; SALARIES AND FRINGE BENEFITS;

EID: 84872681374     PISSN: 09587578     EISSN: 13653148     Source Type: Journal    
DOI: 10.1111/j.1365-3148.2012.01201.x     Document Type: Article

References (24)

1. Beaute, J., Levy, P., Millet, V. et al. (2010) Economic evaluation of immunoglobulin replacement in patients with primary antibody deficiencies. Clinical and Experimental Immunology, 160, 240-245.
2. Berger, M. (2004) Subcutaneous immunoglobulin replacement in primary immunodeficiencies. Clinical Immunology, 112, 1-7.
3. Berger, M. (2008) Principles of and advances in immunoglobulin replacement therapy for primary immunodeficiency. Immunology and Allergy Clinics of North America, 28, 413-437.
4. British Columbia Nurses' Union. Wage grid. British Columbia Nurses' Union. 2011. URL http://www.bcnu.org/contracts_services/provincial_contract/pdf/wage_grid.pdf (Accessed 14/12/11).
5. Chapel, H.M., Spickett, G.P., Ericson, D., Engl, W., Eibl, M.M. & Bjorkander, J. (2000) The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy. Journal of Clinical Immunology, 20, 94-100.
6. Chinen, J. & Shearer, W.T. (2010) Secondary immunodeficiencies, including HIV infection. The Journal of Allergy and Clinical Immunology, 125, S195-S203.
7. Gardulf, A., Andersen, V., Bjorkander, J. et al. (1995) Subcutaneous immunoglobulin replacement in patients with primary antibody deficiencies: safety and costs. Lancet, 345, 365-369.
8. Gardulf, A., Nicolay, U., Math, D. et al. (2004) Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home. The Journal of Allergy and Clinical Immunology, 114, 936-942.
9. Haddad, L., Perrinet, M., Parent, D., Leroy-Cotteau, A., Toguyeni, E., Condette-Wojtasik, G. & Hachulla, E. (2006) Economic evaluation of at home subcutaneous and intravenous immunoglobulin substitution. La Revue de Médecine Interne, 27, 924-926.
10. Ho, C., Membe, S., and Cimon, K. Subcutaneous versus intravenous immunoglobulin for primary immunodeficiencies: systematic review and economic evaluation. Technology report number 98. Canadian Agency for Drugs and Technologies in Health. 2008. URL http://cadth.ca/en/products/health-technology-assessment/publication/785 (Accessed 27/10/11).
11. Hogy, B., Keinecke, H.O. & Borte, M. (2005) Pharmacoeconomic evaluation of immunoglobulin treatment in patients with antibody deficiencies from the perspective of the German statutory health insurance. The European Journal of Health Economics, 6, 24-29.
12. Hospital Employees' Union. Wage scedules - Schedule B - Rate levels. 2010-2012 Collective agreement. General wage schedule. Hospital Employees' Union. 2011. URL http://www.heu.org/sites/default/files/uploads/collective_agreement/2011/03/16/Facilities%202010%20to%202012%20wage%20rates.pdf (Accessed 14/12/11).
13. Kittner, J.M., Grimbacher, B., Wulff, W., Jager, B. & Schmidt, R.E. (2006) Patients' attitude to subcutaneous immunoglobulin substitution as home therapy. Journal of Clinical Immunology, 26, 400-405.
14. Lemieux, R., Bazin, R. & Neron, S. (2005) Therapeutic intravenous immunoglobulins. Molecular Immunology, 42, 839-848.
15. Liu, Z., Albon, E., and Hyde, C. The effectiveness and cost effectiveness of immunoglobulin replacement therapy for primary immunodeficiency and chronic lymphocytic leukaemia: a systematic review and economic evaluation. The University of Birmingham. 2005. URL www.rep.bham.ac.uk/2005/IgRT.pdf (Accessed 19/10/11).
16. Membe, S.K., Ho, C., Cimon, K., Morrison, A., Kanani, A. & Roifman, C.M. (2008) Economic assessment of different modalities of immunoglobulin replacement therapy. Immunology and Allergy Clinics of North America, 28, 861-874.
17. Misbah, S., Sturzenegger, M.H., Borte, M., Shapiro, R.S., Wasserman, R.L., Berger, M. & Ochs, H.D. (2009) Subcutaneous immunoglobulin: opportunities and outlook. Clinical and Experimental Immunology, 158 (Suppl. 1), 51-59.
18. Nicolay, U., Kiessling, P., Berger, M. et al. (2006) Health-related quality of life and treatment satisfaction in North American patients with primary immunedeficiency diseases receiving subcutaneous IgG self-infusions at home. Journal of Clinical Immunology, 26, 65-72.
19. Product Distribution Centre. 2011. URL http://www.pdc.gov.bc.ca/Account/LogOn (Accessed 13/12/11).
20. Provincial Health Services Authority. Provincial blood coordinating office. Provincial Health Services Authority. 2011. URL http://www.phsa.ca/AgenciesAndServices/Services/PBCO.htm (Accessed 11/11/11).
21. Shapiro, R. (2010) Subcutaneous immunoglobulin therapy by rapid push is preferred to infusion by pump: a retrospective analysis. Journal of Clinical Immunology, 30, 301-307.
22. Shehata, N., Palda, V., Bowen, T. et al. (2010) The use of immunoglobulin therapy for patients with primary immune deficiency: an evidence-based practice guideline. Transfusion Medicine Reviews, 24 (Suppl. 1), S28-S50.
23. Sorensen, R.U. & Moore, C. (2000) Antibody deficiency syndromes. Pediatric Clinics of North America, 47, 1225-1252.
24. Turvey, S.E., Bonilla, F.A. & Junker, A.K. (2009) Primary immunodeficiency diseases: a practical guide for clinicians. Postgraduate Medical Journal, 85, 660-666.