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Volumn 9, Issue 1, 2013, Pages 719-727

Changes in LDL-C levels and goal attainment associated with addition of ezetimibe to simvastatin, atorvastatin, or rosuvastatin compared with titrating statin monotherapy

Author keywords

Atorvastatin; Ezetimibe; Low density lipoprotein cholesterol goal; Rosuvastatin

Indexed keywords

ATORVASTATIN; EZETIMIBE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ROSUVASTATIN; SIMVASTATIN;

EID: 84889813405     PISSN: 11766344     EISSN: 11782048     Source Type: Journal    
DOI: 10.2147/VHRM.S49840     Document Type: Article
Times cited : (29)

References (39)
  • 1
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170, 000 participants in 26 randomised trials
    • Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170, 000 participants in 26 randomised trials. Lancet. 2010;376(9753): 1670-1681.
    • (2010) Lancet , vol.376 , Issue.9753 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3
  • 2
    • 79960205374 scopus 로고    scopus 로고
    • ESC/EAS Guidelines for the management of dyslipidaemias. The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
    • Catapano AL, Reiner Z, De Backer G, et al. ESC/EAS Guidelines for the management of dyslipidaemias. The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Atherosclerosis. 2011;217(1):3-46.
    • (2011) Atherosclerosis , vol.217 , Issue.1 , pp. 3-46
    • Catapano, A.L.1    Reiner, Z.2    De Backer, G.3
  • 3
    • 4544275379 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
    • Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. J Am Coll Cardiol. 2004;44(3):720-732.
    • (2004) J Am Coll Cardiol , vol.44 , Issue.3 , pp. 720-732
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.3
  • 4
    • 77949810266 scopus 로고    scopus 로고
    • Loss of early gains in low-density lipoprotein cholesterol goal attainment among high-risk patients
    • Foody JM, Sajjan SG, Hu XH, et al. Loss of early gains in low-density lipoprotein cholesterol goal attainment among high-risk patients. J Clin Lipidol. 2010;4(2):126-132.
    • (2010) J Clin Lipidol , vol.4 , Issue.2 , pp. 126-132
    • Foody, J.M.1    Sajjan, S.G.2    Hu, X.H.3
  • 5
    • 34548046494 scopus 로고    scopus 로고
    • Intensity of lipid-lowering therapy and low-density lipoprotein cholesterol goal attainment among the elderly before and after the 2004 National Cholesterol Education Program Adult Treatment Panel III update
    • Nichols GA, Nag S, Chan W. Intensity of lipid-lowering therapy and low-density lipoprotein cholesterol goal attainment among the elderly before and after the 2004 National Cholesterol Education Program Adult Treatment Panel III update. Am Heart J. 2007;154(3):554-560.
    • (2007) Am Heart J , vol.154 , Issue.3 , pp. 554-560
    • Nichols, G.A.1    Nag, S.2    Chan, W.3
  • 6
    • 67651111687 scopus 로고    scopus 로고
    • Lipid treatment assessment project 2: A multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals
    • Waters DD, Brotons C, Chiang CW, et al. Lipid treatment assessment project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals. Circulation. 2009;120(1):28-34.
    • (2009) Circulation , vol.120 , Issue.1 , pp. 28-34
    • Waters, D.D.1    Brotons, C.2    Chiang, C.W.3
  • 7
    • 77956659275 scopus 로고    scopus 로고
    • Attainment of low-density lipoprotein cholesterol goals in coronary artery disease
    • Kauffman AB, Olson KL, Youngblood ML, et al. Attainment of low-density lipoprotein cholesterol goals in coronary artery disease. J Clin Lipidol. 2010;4(3):173-180.
    • (2010) J Clin Lipidol , vol.4 , Issue.3 , pp. 173-180
    • Kauffman, A.B.1    Olson, K.L.2    Youngblood, M.L.3
  • 8
    • 79959594328 scopus 로고    scopus 로고
    • Low-density lipoprotein cholesterol target achievement in patients at high risk for coronary heart disease
    • Kitkungvan D, Lynn Fillipon NM, Dani SS, Downey BC. Low-density lipoprotein cholesterol target achievement in patients at high risk for coronary heart disease. J Clin Lipidol. 2010;4(4):293-297.
    • (2010) J Clin Lipidol , vol.4 , Issue.4 , pp. 293-297
    • Kitkungvan, D.1    Lynn Fillipon, N.M.2    Dani, S.S.3    Downey, B.C.4
  • 9
    • 35948976548 scopus 로고    scopus 로고
    • LDL-C goal attainment among patients newly diagnosed with coronary heart disease or diabetes in a commercial HMO
    • Nag SS, Daniel GW, Bullano MF, et al. LDL-C goal attainment among patients newly diagnosed with coronary heart disease or diabetes in a commercial HMO. J Manag Care Pharm. 2007;13(8):652-663.
    • (2007) J Manag Care Pharm , vol.13 , Issue.8 , pp. 652-663
    • Nag, S.S.1    Daniel, G.W.2    Bullano, M.F.3
  • 10
    • 84873478245 scopus 로고    scopus 로고
    • The efficacy and safety of ezetimibe co-administered with statin therapy in various patient groups
    • Catapano AL, Toth PP, Tomassini JE, Tershakovec AM. The efficacy and safety of ezetimibe co-administered with statin therapy in various patient groups. Clin Lipidol. 2012;8(1):13-41.
    • (2012) Clin Lipidol , vol.8 , Issue.1 , pp. 13-41
    • Catapano, A.L.1    Toth, P.P.2    Tomassini, J.E.3    Tershakovec, A.M.4
  • 11
    • 84862827717 scopus 로고    scopus 로고
    • Changes in prescription patterns before and after reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) results and expected effects on low-density lipoprotein-cholesterol reduction
    • Toth PP, Ballantyne CM, Davidson MH et al. Changes in prescription patterns before and after reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) results and expected effects on low-density lipoprotein-cholesterol reduction. J Clin Lipidol. 2012;6(2):180-191.
    • (2012) J Clin Lipidol , vol.6 , Issue.2 , pp. 180-191
    • Toth, P.P.1    Ballantyne, C.M.2    Davidson, M.H.3
  • 12
    • 84889809842 scopus 로고    scopus 로고
    • Crestor (rosuvastatin calcium) tablets [package insert]. Wilmington, DE: AstraZeneca
    • Crestor (rosuvastatin calcium) tablets [package insert]. Wilmington, DE: AstraZeneca; 2013.
    • (2013)
  • 13
    • 84889783529 scopus 로고    scopus 로고
    • Lipitor (atorvastatin calcium) tablets [package insert]. New York, NY: Pfizer
    • Lipitor (atorvastatin calcium) tablets [package insert]. New York, NY: Pfizer; 2013.
    • (2013)
  • 14
    • 84889790884 scopus 로고    scopus 로고
    • Zocor (simvastatin) tablets [package insert]. Whitehouse Station, NJ: Merck & Co, Inc
    • Zocor (simvastatin) tablets [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2012.
    • (2012)
  • 15
    • 84889829518 scopus 로고    scopus 로고
    • Liptruzet (ezetimibe/atorvastatin) [package insert]. Whitehouse Station, NJ: Merck & Co, Inc
    • Liptruzet (ezetimibe/atorvastatin) [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2013.
    • (2013)
  • 16
    • 84889865285 scopus 로고    scopus 로고
    • Vytorin (ezetimibe/simvastatin) [package insert]. Whitehouse Station, NJ: Merck & Co, Inc
    • Vytorin (ezetimibe/simvastatin) [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2013.
    • (2013)
  • 17
    • 2942607406 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia
    • Ballantyne CM, Blazing MA, King TR, Brady WE, Palmisano J. Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia. Am J Cardiol. 2004;93(12):1487-1494.
    • (2004) Am J Cardiol , vol.93 , Issue.12 , pp. 1487-1494
    • Ballantyne, C.M.1    Blazing, M.A.2    King, T.R.3    Brady, W.E.4    Palmisano, J.5
  • 18
    • 17844410923 scopus 로고    scopus 로고
    • Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: The Vytorin Versus Atorvastatin (VYVA) study
    • Ballantyne CM, Abate N, Yuan Z, King TR, Palmisano J. Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study. Am Heart J. 2005;149(3):464-473.
    • (2005) Am Heart J , vol.149 , Issue.3 , pp. 464-473
    • Ballantyne, C.M.1    Abate, N.2    Yuan, Z.3    King, T.R.4    Palmisano, J.5
  • 19
    • 39149117012 scopus 로고    scopus 로고
    • Effect of ezetimibe/simvastatin vs atorvastatin on lowering levels of LDL-C and non-HDL-C, ApoB, and hs-CRP in patients with type 2 diabetes
    • Weinstock RS, Goldberg RB, Guyton JR et al. Effect of ezetimibe/simvastatin vs atorvastatin on lowering levels of LDL-C and non-HDL-C, ApoB, and hs-CRP in patients with type 2 diabetes. J Clin Lipidol. 2008;2(1):25-35.
    • (2008) J Clin Lipidol , vol.2 , Issue.1 , pp. 25-35
    • Weinstock, R.S.1    Goldberg, R.B.2    Guyton, J.R.3
  • 20
    • 11844291388 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemia
    • Bays HE, Ose L, Fraser N et al. A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemia. Clin Ther. 2004;26(11):1758-1773.
    • (2004) Clin Ther , vol.26 , Issue.11 , pp. 1758-1773
    • Bays, H.E.1    Ose, L.2    Fraser, N.3
  • 21
    • 33750531657 scopus 로고    scopus 로고
    • Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients
    • Catapano AL, Davidson MH, Ballantyne CM et al. Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients. Curr Med Res Opin. 2006;22(10):2041-2053.
    • (2006) Curr Med Res Opin , vol.22 , Issue.10 , pp. 2041-2053
    • Catapano, A.L.1    Davidson, M.H.2    Ballantyne, C.M.3
  • 22
    • 18244390229 scopus 로고    scopus 로고
    • A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: The ezetimibe add-on to statin for effectiveness (EASE) trial
    • Pearson TA, Denke MA, McBride PE et al. A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial. Mayo Clin Proc. 2005;80(5):587-595.
    • (2005) Mayo Clin Proc , vol.80 , Issue.5 , pp. 587-595
    • Pearson, T.A.1    Denke, M.A.2    McBride, P.E.3
  • 23
    • 4344630867 scopus 로고    scopus 로고
    • Pharmacodynamic interaction between ezetimibe and rosuvastatin
    • Kosoglou T, Statkevich P, Yang B et al. Pharmacodynamic interaction between ezetimibe and rosuvastatin. Curr Med Res Opin. 2004;20(8):1185-1195.
    • (2004) Curr Med Res Opin , vol.20 , Issue.8 , pp. 1185-1195
    • Kosoglou, T.1    Statkevich, P.2    Yang, B.3
  • 24
    • 33847021434 scopus 로고    scopus 로고
    • Efficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER study)
    • Ballantyne CM, Weiss R, Moccetti T et al. Efficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER study). Am J Cardiol. 2007;99(5):673-680.
    • (2007) Am J Cardiol , vol.99 , Issue.5 , pp. 673-680
    • Ballantyne, C.M.1    Weiss, R.2    Moccetti, T.3
  • 25
    • 52949116801 scopus 로고    scopus 로고
    • Nine-year trends in achievement of risk factor goals in the US and European outpatients with cardiovascular disease
    • Steinberg BA, Bhatt DL, Mehta S, et al. Nine-year trends in achievement of risk factor goals in the US and European outpatients with cardiovascular disease. Am Heart J. 2008;156(4):719-727.
    • (2008) Am Heart J , vol.156 , Issue.4 , pp. 719-727
    • Steinberg, B.A.1    Bhatt, D.L.2    Mehta, S.3
  • 26
    • 66949121771 scopus 로고    scopus 로고
    • Low-density lipoprotein cholesterol goal attainment in high-risk family medicine patients
    • Vande Griend JP, Saseen JJ. Low-density lipoprotein cholesterol goal attainment in high-risk family medicine patients. J Clin Lipidol. 2009;3(3):195-200.
    • (2009) J Clin Lipidol , vol.3 , Issue.3 , pp. 195-200
    • Vande Griend, J.P.1    Saseen, J.J.2
  • 27
    • 78149457142 scopus 로고    scopus 로고
    • Update on the efficacy and safety of combination ezetimibe plus statin therapy
    • Toth PP, Catapano A, Tomassini JE, Tershakovec AM. Update on the efficacy and safety of combination ezetimibe plus statin therapy. Clin Lipidol. 2010;5(5):655-684.
    • (2010) Clin Lipidol , vol.5 , Issue.5 , pp. 655-684
    • Toth, P.P.1    Catapano, A.2    Tomassini, J.E.3    Tershakovec, A.M.4
  • 28
    • 77949953423 scopus 로고    scopus 로고
    • Switching from atorvastatin to simvastatin in patients at high cardiovascular risk: Effects on low-density lipoprotein cholesterol
    • Aronow HD, Hess G, Hill J, Kuznik A, Liu LZ. Switching from atorvastatin to simvastatin in patients at high cardiovascular risk: effects on low-density lipoprotein cholesterol. Am J Ther. 2010;17(2):167-175.
    • (2010) Am J Ther , vol.17 , Issue.2 , pp. 167-175
    • Aronow, H.D.1    Hess, G.2    Hill, J.3    Kuznik, A.4    Liu, L.Z.5
  • 29
    • 67649388476 scopus 로고    scopus 로고
    • Clinical review: Impact of statin substitution policies on patient outcomes
    • Atar D, Carmena R, Clemmensen P, et al. Clinical review: impact of statin substitution policies on patient outcomes. Ann Med. 2009;41(4): 242-256.
    • (2009) Ann Med , vol.41 , Issue.4 , pp. 242-256
    • Atar, D.1    Carmena, R.2    Clemmensen, P.3
  • 31
    • 0038645309 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial)
    • Jones PH, Davidson MH, Stein EA, et al. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial). Am J Cardiol. 2003;92(2):152-160.
    • (2003) Am J Cardiol , vol.92 , Issue.2 , pp. 152-160
    • Jones, P.H.1    Davidson, M.H.2    Stein, E.A.3
  • 33
    • 78649645691 scopus 로고    scopus 로고
    • Switching from high-efficacy lipid-lowering therapies to simvastatin and low-density lipoprotein cholesterol goal attainment in coronary heart disease/coronary heart disease-equivalent patients
    • Tunceli K, Sajjan SG, Ramey DR, et al. Switching from high-efficacy lipid-lowering therapies to simvastatin and low-density lipoprotein cholesterol goal attainment in coronary heart disease/coronary heart disease-equivalent patients. J Clin Lipidol. 2010;4(6):491-500.
    • (2010) J Clin Lipidol , vol.4 , Issue.6 , pp. 491-500
    • Tunceli, K.1    Sajjan, S.G.2    Ramey, D.R.3
  • 34
    • 77649195191 scopus 로고    scopus 로고
    • Therapy modifications and low-density lipoprotein cholesterol goal attainment rates associated with the initiation of generic simvastatin
    • Willey VJ, Bullano MF, Shoetan NN, Gandhi SK. Therapy modifications and low-density lipoprotein cholesterol goal attainment rates associated with the initiation of generic simvastatin. Curr Med Res Opin. 2010;26(1):121-128.
    • (2010) Curr Med Res Opin , vol.26 , Issue.1 , pp. 121-128
    • Willey, V.J.1    Bullano, M.F.2    Shoetan, N.N.3    Gandhi, S.K.4
  • 35
    • 84864915536 scopus 로고    scopus 로고
    • Use of lipid-lowering medications and the likelihood of achieving optimal LDL-cholesterol goals in coronary artery disease patients
    • Karalis DG, Victor B, Ahedor L, Liu L. Use of lipid-lowering medications and the likelihood of achieving optimal LDL-cholesterol goals in coronary artery disease patients. Cholesterol. 2012;2012:861924.
    • (2012) Cholesterol , vol.2012 , pp. 861924
    • Karalis, D.G.1    Victor, B.2    Ahedor, L.3    Liu, L.4
  • 36
    • 77951622890 scopus 로고    scopus 로고
    • An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design
    • Califf RM, Lokhnygina Y, Cannon CP, et al. An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design. Am Heart J. 2010;159(5):705-709.
    • (2010) Am Heart J , vol.159 , Issue.5 , pp. 705-709
    • Califf, R.M.1    Lokhnygina, Y.2    Cannon, C.P.3
  • 37
    • 79959746706 scopus 로고    scopus 로고
    • The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): A randomised placebo-controlled trial
    • Baigent C, Landray MJ, Reith C, et al. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet. 2011;377(9784):2181-2192.
    • (2011) Lancet , vol.377 , Issue.9784 , pp. 2181-2192
    • Baigent, C.1    Landray, M.J.2    Reith, C.3
  • 38
    • 77953233048 scopus 로고    scopus 로고
    • Observed and predicted reduction of ischemic cardiovascular events in the Simvastatin and Ezetimibe in Aortic Stenosis trial
    • Holme I, Boman K, Brudi P, et al. Observed and predicted reduction of ischemic cardiovascular events in the Simvastatin and Ezetimibe in Aortic Stenosis trial. Am J Cardiol. 2010;105(12):1802-1808.
    • (2010) Am J Cardiol , vol.105 , Issue.12 , pp. 1802-1808
    • Holme, I.1    Boman, K.2    Brudi, P.3
  • 39
    • 52649120889 scopus 로고    scopus 로고
    • Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis
    • Rossebo AB, Pedersen TR, Boman K, et al. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. N Engl J Med. 2008;359(13):1343-1356.
    • (2008) N Engl J Med , vol.359 , Issue.13 , pp. 1343-1356
    • Rossebo, A.B.1    Pedersen, T.R.2    Boman, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.