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Volumn 6, Issue 2, 2012, Pages 180-191

Changes in prescription patterns before and after reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) results and expected effects on low-density lipoprotein-cholesterol reduction

Author keywords

ENHANCE; Ezetimibe simvastatin; LDL C; Statin

Indexed keywords

ATORVASTATIN; EZETIMIBE; FLUINDOSTATIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN;

EID: 84862827717     PISSN: 19332874     EISSN: 18764789     Source Type: Journal    
DOI: 10.1016/j.jacl.2011.11.007     Document Type: Article
Times cited : (19)

References (45)
  • 1
    • 4544275379 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
    • S.M. Grundy, J.I. Cleeman, and C.N. Merz Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines J Am Coll Cardiol 44 2004 720 732
    • (2004) J Am Coll Cardiol , vol.44 , pp. 720-732
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.3
  • 3
    • 78149457142 scopus 로고    scopus 로고
    • Update on the efficacy and safety of combination ezetimibe + statin therapy
    • P.P. Toth, A. Catapano, J.E. Tomassini, and A.M. Tershakovec Update on the efficacy and safety of combination ezetimibe + statin therapy Clin Lipidol 5 2010 665 684
    • (2010) Clin Lipidol , vol.5 , pp. 665-684
    • Toth, P.P.1    Catapano, A.2    Tomassini, J.E.3    Tershakovec, A.M.4
  • 4
    • 84862806321 scopus 로고    scopus 로고
    • PA: Merck/Schering-Plough Pharmaceuticals
    • Vytorin [product insert]. N. Wales, PA: Merck/Schering-Plough Pharmaceuticals; 2010.
    • (2010) Vytorin [Product Insert]
    • Wales, N.1
  • 8
    • 11844250533 scopus 로고    scopus 로고
    • Long-term safety and efficacy of high-dose atorvastatin treatment in patients with familial hypercholesterolemia
    • DOI 10.1016/j.amjcard.2004.09.015, PII S000291490401536X
    • S. van Wissen, T.J. Smilde, and M.D. Trip Long-term safety and efficacy of high-dose atorvastatin treatment in patients with familial hypercholesterolemia Am J Cardiol 95 2005 264 266 (Pubitemid 40092097)
    • (2005) American Journal of Cardiology , vol.95 , Issue.2 , pp. 264-266
    • Van Wissen, S.1    Smilde, T.J.2    Trip, M.D.3    Stalenhoef, A.F.H.4    Kastelein, J.J.P.5
  • 9
    • 53449101871 scopus 로고    scopus 로고
    • Commentary on the implications of the ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression) Trial: Should ezetimibe move to the "back of the line" as a therapy for dyslipidemia?
    • P.P. Toth, and K.A. Maki Commentary on the implications of the ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression) Trial: should ezetimibe move to the "back of the line" as a therapy for dyslipidemia? J Clin Lipidol 2 2008 313 317
    • (2008) J Clin Lipidol , vol.2 , pp. 313-317
    • Toth, P.P.1    Maki, K.A.2
  • 10
    • 51249083779 scopus 로고    scopus 로고
    • Is ezetimibe/simvastatin no better than simvastatin alone? Lessons learned and clinical implications
    • M.H. Davidson Is ezetimibe/simvastatin no better than simvastatin alone? Lessons learned and clinical implications Cleve Clin J Med 75 2008 479 496
    • (2008) Cleve Clin J Med , vol.75 , pp. 479-496
    • Davidson, M.H.1
  • 13
    • 84862796987 scopus 로고    scopus 로고
    • Princeton, NJ: Bristol-Meyers Squibb
    • Pravachol [package insert]. Princeton, NJ: Bristol-Meyers Squibb; 2011.
    • (2011) Pravachol [Package Insert]
  • 15
    • 84862831015 scopus 로고    scopus 로고
    • Whitehouse Station, NJ: Merck & Co. Inc.
    • Mevacor [product insert]. Whitehouse Station, NJ: Merck & Co. Inc.; 2010.
    • (2010) Mevacor [Product Insert]
  • 16
    • 84862831962 scopus 로고    scopus 로고
    • Zetia [product insert]. N. Wales, PA: Merck/Schering-Plough Pharmaceuticals; 2011
    • Zetia [product insert]. N. Wales, PA: Merck/Schering-Plough Pharmaceuticals; 2011.
  • 19
    • 41649106758 scopus 로고    scopus 로고
    • Does ENHANCE diminish confidence in lowering LDL or in ezetimibe?
    • DOI 10.1056/NEJMe0801608
    • B.G. Brown, and A.J. Taylor Does ENHANCE diminish confidence in lowering LDL or in ezetimibe? N Engl J Med 358 2008 1504 1507 (Pubitemid 351482746)
    • (2008) New England Journal of Medicine , vol.358 , Issue.14 , pp. 1504-1507
    • Brown, B.G.1    Taylor, A.J.2
  • 21
    • 84862792338 scopus 로고    scopus 로고
    • American Heart Association
    • American Heart Association. Statement from the American Heart Association on ENHANCE study results. 2008. Available at: http://www.fda.gov/Drugs/ DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ DrugSafetyInformationforHeathcareProfessionals/ucm079524.htm.
    • (2008) Statement from the American Heart Association on ENHANCE Study Results
  • 22
    • 57449105069 scopus 로고    scopus 로고
    • Effect of statins alone versus statins plus ezetimibe on carotid atherosclerosis in type 2 diabetes: The SANDS (Stop Atherosclerosis in Native Diabetics Study) trial
    • J.L. Fleg, M. Mete, and B.V. Howard Effect of statins alone versus statins plus ezetimibe on carotid atherosclerosis in type 2 diabetes: the SANDS (Stop Atherosclerosis in Native Diabetics Study) trial J Am Coll Cardiol 52 2008 2198 2205
    • (2008) J Am Coll Cardiol , vol.52 , pp. 2198-2205
    • Fleg, J.L.1    Mete, M.2    Howard, B.V.3
  • 23
    • 67650475384 scopus 로고    scopus 로고
    • The VYtorin on Carotid intima-media thickness and overall arterial rigidity (VYCTOR) study
    • A. Meaney, G. Ceballos, and J. Asbun The VYtorin on Carotid intima-media thickness and overall arterial rigidity (VYCTOR) study J Clin Pharmacol 49 2009 838 847
    • (2009) J Clin Pharmacol , vol.49 , pp. 838-847
    • Meaney, A.1    Ceballos, G.2    Asbun, J.3
  • 24
    • 79960822851 scopus 로고    scopus 로고
    • National Institutes of Health Accessed December 7, 2011
    • National Institutes of Health. NIH stops clinical trial on combination cholesterol treatment. Available at: http://www.nih.gov/news/health/may2011/ nhlbi-26.htm. Accessed December 7, 2011.
    • NIH Stops Clinical Trial on Combination Cholesterol Treatment
  • 25
    • 84856217997 scopus 로고    scopus 로고
    • National Heart Lung, and Blood Institute Accessed December 7, 2011
    • National Heart Lung, and Blood Institute. Niacin Plus Statin to Prevent Vascular Events. 2005. Available at: http://clinicaltrials.gov/show/NCT00120289. Accessed December 7, 2011.
    • (2005) Niacin Plus Statin to Prevent Vascular Events
  • 28
    • 0034802407 scopus 로고    scopus 로고
    • Coadministration of colesevelam hydrochloride with atorvastatin lowers LDL cholesterol additively
    • DOI 10.1016/S0021-9150(01)00437-3, PII S0021915001004373
    • D. Hunninghake, W. Insull, and P. Toth Coadministration of colesevelam hydrochloride with atorvastatin lowers LDL cholesterol additively Atherosclerosis 158 2001 407 416 (Pubitemid 32913651)
    • (2001) Atherosclerosis , vol.158 , Issue.2 , pp. 407-416
    • Hunninghake, D.1    Insull Jr., W.2    Toth, P.3    Davidson, D.4    Donovan, J.M.5    Burke, S.K.6
  • 29
    • 77951704587 scopus 로고    scopus 로고
    • Effects of combination lipid therapy in type 2 diabetes mellitus
    • H.N. Ginsberg, M.B. Elam, and L.C. Lovato Effects of combination lipid therapy in type 2 diabetes mellitus N Engl J Med 362 2010 1563 1574
    • (2010) N Engl J Med , vol.362 , pp. 1563-1574
    • Ginsberg, H.N.1    Elam, M.B.2    Lovato, L.C.3
  • 31
    • 77954544624 scopus 로고    scopus 로고
    • Drug treatment of hyperlipidaemia: A guide to the rational use of lipid-lowering drugs
    • P.P. Toth Drug treatment of hyperlipidaemia: a guide to the rational use of lipid-lowering drugs Drugs 70 2010 1363 1379
    • (2010) Drugs , vol.70 , pp. 1363-1379
    • Toth, P.P.1
  • 32
    • 78649645691 scopus 로고    scopus 로고
    • Switching from high-efficacy lipid-lowering therapies to simvastatin and low-density lipoprotein cholesterol goal attainment in coronary heart disease/coronary heart disease-equivalent patients
    • K. Tunceli, S.G. Sajjan, and D.R. Ramey Switching from high-efficacy lipid-lowering therapies to simvastatin and low-density lipoprotein cholesterol goal attainment in coronary heart disease/coronary heart disease-equivalent patients J Clin Lipidol 4 2010 491 500
    • (2010) J Clin Lipidol , vol.4 , pp. 491-500
    • Tunceli, K.1    Sajjan, S.G.2    Ramey, D.R.3
  • 33
    • 77949953423 scopus 로고    scopus 로고
    • Switching from atorvastatin to simvastatin in patients at high cardiovascular risk: Effects on low-density lipoprotein cholesterol
    • H.D. Aronow, G. Hess, J. Hill, A. Kuznik, and L.Z. Liu Switching from atorvastatin to simvastatin in patients at high cardiovascular risk: effects on low-density lipoprotein cholesterol Am J Ther 17 2010 167 175
    • (2010) Am J Ther , vol.17 , pp. 167-175
    • Aronow, H.D.1    Hess, G.2    Hill, J.3    Kuznik, A.4    Liu, L.Z.5
  • 34
    • 67649388476 scopus 로고    scopus 로고
    • Clinical review: Impact of statin substitution policies on patient outcomes
    • D. Atar, R. Carmena, and P. Clemmensen Clinical review: impact of statin substitution policies on patient outcomes Ann Med 41 2009 242 256
    • (2009) Ann Med , vol.41 , pp. 242-256
    • Atar, D.1    Carmena, R.2    Clemmensen, P.3
  • 35
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins
    • Cholesterol Treatment Trialists' (CTT) Collaborators
    • Cholesterol Treatment Trialists' (CTT) Collaborators Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins Lancet 366 2005 1267 1278
    • (2005) Lancet , vol.366 , pp. 1267-1278
  • 36
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170 000 participants in 26 randomised trials
    • C. Baigent, L. Blackwell, and J. Emberson Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials Lancet 376 2010 1670 1681
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3
  • 37
    • 29444440835 scopus 로고    scopus 로고
    • Statin therapy for prevention and treatment of acute and chronic cardiovascular disease: Update on recent trials and metaanalyses
    • M. Briel, A.J. Nordmann, and H.C. Bucher Statin therapy for prevention and treatment of acute and chronic cardiovascular disease: update on recent trials and metaanalyses Curr Opin Lipidol 16 2005 601 605 (Pubitemid 43012155)
    • (2005) Current Opinion in Lipidology , vol.16 , Issue.6 , pp. 601-605
    • Briel, M.1    Nordmann, A.J.2    Bucher, H.C.3
  • 40
    • 79956099377 scopus 로고    scopus 로고
    • Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: Systematic review and meta-analysis
    • D.P. Mikhailidis, R.W. Lawson, and A.L. McCormick Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-analysis Curr Med Res Opin 27 2011 1191 1210
    • (2011) Curr Med Res Opin , vol.27 , pp. 1191-1210
    • Mikhailidis, D.P.1    Lawson, R.W.2    McCormick, A.L.3
  • 41
    • 77951622890 scopus 로고    scopus 로고
    • An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design
    • R.M. Califf, Y. Lokhnygina, and C.P. Cannon An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design Am Heart J 159 2010 705 709
    • (2010) Am Heart J , vol.159 , pp. 705-709
    • Califf, R.M.1    Lokhnygina, Y.2    Cannon, C.P.3
  • 42
    • 50949102416 scopus 로고    scopus 로고
    • Design and Rationale of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of Ezetimibe/Simvastatin versus Simvastatin Monotherapy on Cardiovascular Outcomes in Patients with Acute Coronary Syndrome
    • IMPROVE-IT investigators
    • C.P. Cannon, R.P. Guigliano, M.A. Blazing IMPROVE-IT investigators Design and Rationale of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of Ezetimibe/Simvastatin versus Simvastatin Monotherapy on Cardiovascular Outcomes in Patients with Acute Coronary Syndrome Am Heart J 156 2008 826 832
    • (2008) Am Heart J , vol.156 , pp. 826-832
    • Cannon, C.P.1    Guigliano, R.P.2    Blazing, M.A.3
  • 43
    • 79959746706 scopus 로고    scopus 로고
    • The effects of lowering LDL cholesterol with simvastatin plus ezetmibie in patients with chronic kidney disease (Study of Heart and Renal Protection): A randomized placebo-controlled trial
    • 2181-1292
    • C. Baigent, M.J. Landray, and C. Reith The effects of lowering LDL cholesterol with simvastatin plus ezetmibie in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomized placebo-controlled trial Lancet 377 2011 2181-1292
    • (2011) Lancet , vol.377
    • Baigent, C.1    Landray, M.J.2    Reith, C.3
  • 44
    • 52649120889 scopus 로고    scopus 로고
    • Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis
    • A.B. Rossebo, T.R. Pedersen, and K. Boman Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis N Engl J Med 359 2008 1343 1356
    • (2008) N Engl J Med , vol.359 , pp. 1343-1356
    • Rossebo, A.B.1    Pedersen, T.R.2    Boman, K.3
  • 45
    • 77953233048 scopus 로고    scopus 로고
    • Observed and predicted reduction of ischemic cardiovascular events in the Simvastatin and Ezetimibe in Aortic Stenosis trial
    • I. Holme, K. Boman, and P. Brudi Observed and predicted reduction of ischemic cardiovascular events in the Simvastatin and Ezetimibe in Aortic Stenosis trial Am J Cardiol 105 2010 1802 1808
    • (2010) Am J Cardiol , vol.105 , pp. 1802-1808
    • Holme, I.1    Boman, K.2    Brudi, P.3


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