Pruritus in the older patient: A clinical review

JAMA

Volumn 310, Issue 22, 2013, Pages 2443-2450

  Berger, Timothy G ^a   Shive, Melissa ^a   Harper, G Michael ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID DERIVATIVE; AMIODARONE; BUTORPHANOL; CALCIUM CHANNEL BLOCKING AGENT; CAPSAICIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GABAPENTIN; HYDROCHLOROTHIAZIDE; NALTREXONE; NONSTEROID ANTIINFLAMMATORY AGENT; OXATOMIDE; PREGABALIN; QUININE; TETRACYCLINE; THIAZIDE DIURETIC AGENT; TRIAMCINOLONE;

BULLOUS PEMPHIGOID; CLINICAL EVALUATION; DRUG COST; DRUG DOSE INCREASE; ECZEMA; GERIATRIC CARE; GERIATRIC PATIENT; HUMAN; INTERTRIGO; LOTION; MEDICAL HISTORY; MYCOSIS FUNGOIDES; NEURODERMATITIS; PHOTOTHERAPY; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PRURITUS; RASH; REVIEW; SCABIES; SEBORRHEIC DERMATITIS; SEBORRHEIC KERATOSIS; SENSORY NEUROPATHY; TINEA PEDIS; TRANSIENT ACANTHOLYTIC DERMATOSIS; XEROSIS; AGED; COMPLICATION; DIFFERENTIAL DIAGNOSIS; DRUG ERUPTION; ICHTHYOSIS; PERIPHERAL NEUROPATHY;

AGED; DIAGNOSIS, DIFFERENTIAL; DRUG ERUPTIONS; HUMANS; ICHTHYOSIS; PERIPHERAL NERVOUS SYSTEM DISEASES; PRURITUS;

EID: 84889804440     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2013.282023     Document Type: Review

References (60)

1. Kini SP, DeLong LK, Veledar E, McKenzie-Brown AM, Schaufele M, Chen SC. The impact of pruritus on quality of life: the skin equivalent of pain. Arch Dermatol. 2011;147(10):1153-1156.
2. Matterne U, Apfelbacher CJ, Loerbroks A, et al. Prevalence, correlates and characteristics of chronic pruritus: a population-based cross-sectional study. Acta Derm Venereol. 2011;91(6):674-679.
3. Weisshaar E, Dalgard F. Epidemiology of itch: adding to the burden of skin morbidity. Acta Derm Venereol. 2009;89(4):339-350.
4. Berger TG, Steinhoff M. Pruritus in elderly patients - eruptions of senescence. Semin Cutan Med Surg. 2011;30(2):113-117.
5. Shive M, Linos E, Berger T, Wehner M, Chren MM. Itch as a patient-reported symptom in ambulatory care visits in the United States. J Am Acad Dermatol. 2013;69(4):550-556. .
6. Beauregard S, Gilchrest BA. A survey of skin problems and skin care regimens in the elderly. Arch Dermatol. 1987;123(12):1638-1643.
7. Yalçin B, Tamer E, Toy GG, Oztaş P, Hayran M, Alli N. The prevalence of skin diseases in the elderly: analysis of 4099 geriatric patients. Int J Dermatol. 2006;45(6):672-676.
8. Verhoeven EW, de Klerk S, Kraaimaat FW, van de Kerkhof PC, de Jong EM, Evers AW. Biopsychosocial mechanisms of chronic itch in patients with skin diseases: a review. Acta Derm Venereol. 2008;88(3):211-218.
9. Zachariae R, Lei U, Haedersdal M, Zachariae C. Itch severity and quality of life in patients with pruritus: preliminary validity of a Danish adaptation of the itch severity scale. Acta Derm Venereol. 2012;92(5):508-514.
10. Choi EH, Man MQ, Xu P, et al. Stratum corneum acidification is impaired in moderately aged human and murine skin. J Invest Dermatol. 2007;127(12):2847-2856.
11. Ghadially R, Brown BE, Sequeira-Martin SM, Feingold KR, Elias PM. The aged epidermal permeability barrier: structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model. J Clin Invest. 1995;95(5):2281-2290.
12. Paul C, Maumus-Robert S, Mazereeuw-Hautier J, Guyen CN, Saudez X, Schmitt AM. Prevalence and risk factors for xerosis in the elderly: a cross-sectional epidemiological study in primary care. Dermatology. 2011;223(3):260-265.
13. Arnold CR, Wolf J, Brunner S, Herndler- Brandstetter D, Grubeck-Loebenstein B. Gain and loss of T cell subsets in old age - age-related reshaping of the T cell repertoire. J Clin Immunol. 2011;31(2):137-146.
14. Busse PJ, Mathur SK. Age-related changes in immune function: effect on airway inflammation. J Allergy Clin Immunol. 2010;126(4):690-699; quiz 700-701.
15. Yamaoka H, Sasaki H, Yamasaki H, et al. Truncal pruritus of unknown origin may be a symptom of diabetic polyneuropathy. Diabetes Care. 2010;33(1):150-155.
16. Teoh YL, Yeo BKW, Koh MJA, Teo RYL. Pruritus in the elderly and its impact on quality of life. J Am Acad Dermatol. 2012;66(4)(suppl 1):AB11.
17. Ko MJ, Chiu HC, Jee SH, Hu FC, Tseng CH. Postprandial blood glucose is associated with generalized pruritus in patients with type 2 diabetes [published online September 3, 2013]. Eur J Dermatol. doi:10.1684/ejd.2013.2100.
18. Cohen AD, Vander T, Medvendovsky E, et al. Neuropathic scrotal pruritus: anogenital pruritus is a symptom of lumbosacral radiculopathy. J Am Acad Dermatol. 2005;52(1):61-66.
19. Furue M, Ebata T, Ikoma A, et al. Verbalizing extremes of the visual analogue scale for pruritus: a consensus statement. Acta Derm Venereol. 2013;93(2):214-215.
20. Lay CJ, Wang CL, Chuang HY, et al. Risk factors for delayed diagnosis of scabies in hospitalized patients from long-term care facilities. J Clin Med Res. 2011;3(2):72-77.
21. Wilson MM, Philpott CD, Breer WA. Atypical presentation of scabies among nursing home residents. J Gerontol A Biol Sci Med Sci. 2001;56(7):M424-M427.
22. Joly P, Benoit-Corven C, Baricault S, et al. Chronic eczematous eruptions of the elderly are associated with chronic exposure to calcium channel blockers: results from a case-control study. J Invest Dermatol. 2007;127(12):2766-2771.
23. Reich A, Ständer S, Szepietowski JC. Drug-induced pruritus: a review. Acta Derm Venereol. 2009;89(3):236-244.
24. Montoro de Francisco A, García-Luque A, Fernández M, Puerro M. Side effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists: are we facing a new syndrome? Am J Cardiol. 2012;110(10):1552-1553.
25. Kowalski ML, Makowska JS, Blanca M, et al. Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) - classification, diagnosis and management: review of the EAACI/ENDA and GA2LEN/HANNA. Allergy. 2011;66(7):818-829.
26. Tey HL, Yosipovitch G. Itch in ethnic populations. Acta Derm Venereol. 2010;90(3):227-234.
27. Orme S, da Costa D. Generalised pruritus associated with amlodipine. BMJ. 1997;315(7106):463.
28. Pétavy-Catala C, Martin L, Fontès V, Lorette G, Vaillant L. Hydrochlorothiazide-induced acute generalized exanthematous pustulosis. Acta Derm Venereol. 2001;81(3):209.
29. Summers EM, Bingham CS, Dahle KW, Sweeney C, Ying J, Sontheimer RD. Chronic eczematous eruptions in the aging: further support for an association with exposure to calcium channel blockers. JAMA Dermatol. 2013;149(7):814-818.
30. Drucker AM, Rosen CF. Drug-induced photosensitivity: culprit drugs, management and prevention. Drug Saf. 2011;34(10):821-837.
31. Burgess IF. Understanding scabies. Nurs Times. 2003;99(7):44-45.
32. Reich A, Ständer S, Szepietowski JC. Pruritus in the elderly. Clin Dermatol. 2011;29(1):15-23.
33. Solak Y, Biyik Z, Atalay H, et al. Pregabalin vs gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study. Nephrology (Carlton). 2012;17(8):710-717.
34. Ko MJ, Yang JY, Wu HY, et al. Narrowband ultraviolet B phototherapy for patients with refractory uraemic pruritus: a randomized controlled trial. Br J Dermatol. 2011;165(3):633-639.
35. Bergasa NV. Update on the treatment of the pruritus of cholestasis. Clin Liver Dis. 2008;12(1):219-234.
36. Decock S, Roelandts R, Steenbergen WV, et al. Cholestasis-induced pruritus treated with ultraviolet B phototherapy: an observational case series study. J Hepatol. 2012;57(3):637-641.
37. Centers for Medicare & Medicaid Services. Physician fee schedule. http://www.cms.gov/apps/physician-fee-schedule/search/search-results.aspx?Y= 0&T=0&HT=0&CT=3&H1=96910&M=5. Accessed November 13, 2013.
38. Steinhoff M, Cevikbas F, Ikoma A, Berger TG. Pruritus: management algorithms and experimental therapies. Semin Cutan Med Surg. 2011;30(2):127-137.
39. Gutman AB, Kligman AM, Sciacca J, James WD. Soak and smear: a standard technique revisited. Arch Dermatol. 2005;141(12):1556-1559.
40. Pei AY, Chan HH, Ho KM. The effectiveness of wet wrap dressings using 0.1% mometasone furoate and 0.005% fluticasone proprionate ointments in the treatment of moderate to severe atopic dermatitis in children. Pediatr Dermatol. 2001;18(4):343-348.
41. Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988;319(26):1701-1707.
42. Andersen F, Andersen KH, Kligman AM. Efficacy of an aluminum oxide scrub cream in the treatment of xerotic skin of the elderly. Exog Dermatol. 2004;3(1):30-34.
43. Bingham LG, Noble JW, Davis MD. Wet dressings used with topical corticosteroids for pruritic dermatoses: a retrospective study. J Am Acad Dermatol. 2009;60(5):792-800.
44. Kligman AM, Frosch PJ. Steroid addiction. Int J Dermatol. 1979;18(1):23-31.
45. Weisshaar E. Successful treatment of genital pruritus using topical immunomodulators as a single therapy in multi-morbid patients. Acta Derm Venereol. 2008;88(2):195-196.
46. Salem HH, Van der Weyden MB, Young IF, Wiley JS. Pruritus and severe iron deficiency in polycythaemia vera. Br Med J (Clin Res Ed). 1982;285(6335):91-92.
47. Lewiecki EM, Rahman F. Pruritus: a manifestation of iron deficiency. JAMA. 1976;236(20):2319-2320.
48. Vickers CF. Iron deficiency and the skin. Br J Dermatol. 1973;89(suppl 9):10.
49. Valsecchi R, Cainelli T. Generalized pruritus: a manifestation of iron deficiency. Arch Dermatol. 1983;119(8):630.
50. Zylicz Z, Krajnik M, Sorge AAV, Costantini M. Paroxetine in the treatment of severe non-dermatological pruritus: a randomized, controlled trial. J Pain Symptom Manage. 2003;26(6):1105-1112.
51. Tefferi A, Fonseca R. Selective serotonin reuptake inhibitors are effective in the treatment of polycythemia vera-associated pruritus. Blood. 2002;99(7):2627.
52. Yilmaz S, Ceyhan AM, Baysal Akkaya V. Brachioradial pruritus successfully treated with gabapentin. J Dermatol. 2010;37(7):662-665.
53. De Ridder D, Hans G, Pals P, Menovsky T. A C-fiber-mediated neuropathic brachioradial pruritus. J Neurosurg. 2010;113(1):118-121.
54. Stellon A. Neurogenic pruritus: an unrecognised problem? a retrospective case series of treatment by acupuncture. Acupunct Med. 2002;20(4):186-190.
55. Dupont C, de Maubeuge J, Kotlar W, Lays Y, Masson M. Oxatomide in the treatment of pruritus senilis: a double-blind placebo-controlled trial. Dermatologica. 1984;169(6):348-353.
56. American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2012;60(4):616-631.
57. Yosipovitch G, Bernhard JD. Chronic pruritus. N Engl J Med. 2013;368(17):1625-1634.
58. Fargo MV, Latimer KM. Evaluation and management of common anorectal conditions. Am Fam Physician. 2012;85(6):624-630.
59. MacLean J, Russell D. Pruritus ani. Aust Fam Physician. 2010;39(6):366-370.
60. Markell KW, Billingham RP. Pruritus ani: etiology and management. Surg Clin North Am. 2010;90(1):125-135.